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alprazolam and Absence Seizure

alprazolam has been researched along with Absence Seizure in 24 studies

Alprazolam: A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
alprazolam : A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individuals that have taken this drug.

Research Excerpts

ExcerptRelevanceReference
"This is a case report of severe psychosis and seizures following abrupt discontinuation of alprazolam and then the recurrence of seizures at the end of a gradual tapering schedule."7.68Death following suspected alprazolam withdrawal seizures: a case report. ( Bryant, SG; Haque, W; Watson, DJ, 1990)
"A case is reported of delirium and seizures due to the abrupt withdrawal from the benzodiazepine alprazolam."7.67Delirium and seizures due to abrupt alprazolam withdrawal: case report. ( Levy, AB, 1984)
"Seizures were observed following the withdrawal of alprazolam administered in therapeutic dose for 10 weeks."7.67Seizures following the withdrawal of alprazolam. ( Clancy, J; Coryell, WH; Crowe, RR; Gabel, J; Noyes, R; Perry, PJ; Yamada, T, 1986)
" Reported here is the occurrence of myoclonic seizures after the abrupt discontinuation of phenelzine and alprazolam."7.67Myoclonic seizures after abrupt withdrawal from phenelzine and alprazolam. ( Cameron, O; Grunhaus, L; Naylor, MW, 1987)
"0 mg doses of Staccato alprazolam demonstrated efficacy in rapidly terminating seizures in an inpatient setting and were well tolerated."5.69A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination. ( Biton, V; Dave, H; Detyniecki, K; DiVentura, B; French, J; Gelfand, MA; Gong, H; Isojarvi, J; Liow, K; O'Brien, TJ; Reich, B; Sadek, A, 2023)
"alprazolam and ketamine, was tested in two types of seizure activity."5.30Effect of alprazolam and ketamine on seizures induced by two different convulsants. ( Herink, J, 1997)
"We evaluated racemic zopiclone, its (S)- and (R)-enantiomers and a metabolite, (S)-desmethylzopiclone, for their actions on locomotor activity, rotarod performance, the elevated plus maze and the Vogel conflict test of anxiety, and electroconvulsive shock-induced seizures duration."3.71Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite. ( Carlson, JN; Glick, SD; Haskew, R; Jerussi, TP; Maisonneuve, IM; Wacker, J, 2001)
"This is a case report of severe psychosis and seizures following abrupt discontinuation of alprazolam and then the recurrence of seizures at the end of a gradual tapering schedule."3.68Death following suspected alprazolam withdrawal seizures: a case report. ( Bryant, SG; Haque, W; Watson, DJ, 1990)
"A case is reported of delirium and seizures due to the abrupt withdrawal from the benzodiazepine alprazolam."3.67Delirium and seizures due to abrupt alprazolam withdrawal: case report. ( Levy, AB, 1984)
"Seizures were observed following the withdrawal of alprazolam administered in therapeutic dose for 10 weeks."3.67Seizures following the withdrawal of alprazolam. ( Clancy, J; Coryell, WH; Crowe, RR; Gabel, J; Noyes, R; Perry, PJ; Yamada, T, 1986)
" Reported here is the occurrence of myoclonic seizures after the abrupt discontinuation of phenelzine and alprazolam."3.67Myoclonic seizures after abrupt withdrawal from phenelzine and alprazolam. ( Cameron, O; Grunhaus, L; Naylor, MW, 1987)
" The majority (67%) of patients interviewed discontinued alprazolam for a period of at least 3 days after a gradual dosage reduction schedule over a 4-week period at the end of the long-term treatment study."2.67Discontinuation of alprazolam after long-term treatment of panic-related disorders. ( Ballenger, JC; Burrows, GD; DuPont, RL; Noyes, R; Pecknold, JC; Rifkin, A; Rubin, RT; Swinson, RP, 1992)
"Oxazepam is an anxiolytic with established clinical efficacy."2.38Oxazepam: update 1989. ( Ayd, FJ, 1990)
"alprazolam and ketamine, was tested in two types of seizure activity."1.30Effect of alprazolam and ketamine on seizures induced by two different convulsants. ( Herink, J, 1997)
"Pentylenetetrazole-induced seizure thresholds were similar in mice treated for 14 days with lorazepam or alprazolam, 2 mg/kg/day."1.29Chronic benzodiazepine administration. XII. Anticonvulsant cross-tolerance but distinct neurochemical effects of alprazolam and lorazepam. ( Byrnes, JJ; Greenblatt, DJ; Miller, LG; Shader, RI, 1993)
"Treatment with carbamazepine attenuated (P less than 0."1.28Chronic benzodiazepine administration. IX. Attenuation of alprazolam discontinuation effects by carbamazepine. ( Browne, TR; Galpern, WR; Greenblatt, DJ; Miller, LG; Shader, RI; Szabo, GK, 1991)
"All had withdrawal symptoms, six demonstrated tolerance, and at least four had substantial social or occupational impairment secondary to drug use."1.27Alprazolam dependence in seven patients. ( Juergens, SM; Morse, RM, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's12 (50.00)18.2507
2000's3 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Gall, M1
Lahti, RA1
Rudzik, AD1
Duchamp, DJ1
Chidester, C1
Scahill, T1
French, J1
Biton, V1
Dave, H1
Detyniecki, K1
Gelfand, MA1
Gong, H1
Liow, K1
O'Brien, TJ1
Sadek, A1
DiVentura, B1
Reich, B1
Isojarvi, J1
Mena Martín, FJ1
Dueñas Laita, A1
Pérez Castrillón, JL1
Martín Escudero, JC1
Levy, AB1
Rudorfer, MV1
Golden, RN2
Potter, WZ1
Byrnes, JJ1
Miller, LG2
Greenblatt, DJ2
Shader, RI2
Cannizzaro, C1
Cannizzaro, E1
Gagliano, M1
Mangiapane, N1
Freeman, S1
Herink, J2
Jenck, F1
Wichmann, J1
Dautzenberg, FM1
Moreau, JL1
Ouagazzal, AM1
Martin, JR1
Lundstrom, K1
Cesura, AM1
Poli, SM1
Roever, S1
Kolczewski, S1
Adam, G1
Kilpatrick, G1
Carlson, JN1
Haskew, R1
Wacker, J1
Maisonneuve, IM1
Glick, SD1
Jerussi, TP1
DuPont, RL1
Swinson, RP1
Ballenger, JC1
Burrows, GD1
Noyes, R2
Rubin, RT1
Rifkin, A1
Pecknold, JC1
Galpern, WR1
Szabo, GK1
Browne, TR1
Koupilová, M1
Hrdina, V1
Sloan, JW1
Martin, WR1
Wala, EP1
Ayd, FJ1
Entman, ML1
Haque, W1
Watson, DJ1
Bryant, SG1
Warner, MD1
Peabody, CA1
Boutros, NN1
Whiteford, HA1
Perry, PJ1
Crowe, RR1
Coryell, WH1
Clancy, J1
Yamada, T1
Gabel, J1
Brown, TM1
Miller, H1
Evans, DL1
Juergens, SM1
Morse, RM1
Patterson, WM1
Naylor, MW1
Grunhaus, L1
Cameron, O1

Reviews

3 reviews available for alprazolam and Absence Seizure

ArticleYear
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial

1984
Oxazepam: update 1989.
    International clinical psychopharmacology, 1990, Volume: 5, Issue:1

    Topics: Aged; Alcoholism; Alprazolam; Female; Humans; Oxazepam; Seizures; Substance Withdrawal Syndrome; Sub

1990
The new antidepressants.
    North Carolina medical journal, 1988, Volume: 49, Issue:10

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Fluoxetine; Maprotiline; Nomifensine; Seizures; Trazod

1988

Trials

3 trials available for alprazolam and Absence Seizure

ArticleYear
A randomized phase 2b efficacy study in patients with seizure episodes with a predictable pattern using Staccato® alprazolam for rapid seizure termination.
    Epilepsia, 2023, Volume: 64, Issue:2

    Topics: Adult; Alprazolam; Anticonvulsants; Double-Blind Method; Epilepsy; Humans; Seizures; Treatment Outco

2023
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial

1984
Discontinuation of alprazolam after long-term treatment of panic-related disorders.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Adult; Alprazolam; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Follow

1992

Other Studies

19 other studies available for alprazolam and Absence Seizure

ArticleYear
Novel anxiolytic agents derived from alpha-amino-alpha-phenyl-o-tolyl-4H-triazoles and -imidazoles.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Crystallography; Hypnotics and Sedatives; Imid

1978
[Seizures as late manifestation of alprazolam withdrawal syndrome].
    Medicina clinica, 2002, Dec-07, Volume: 119, Issue:20

    Topics: Alprazolam; Anti-Anxiety Agents; Humans; Male; Middle Aged; Seizures; Substance Withdrawal Syndrome;

2002
Delirium and seizures due to abrupt alprazolam withdrawal: case report.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:1

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Delirium; Half-Life; Huma

1984
Chronic benzodiazepine administration. XII. Anticonvulsant cross-tolerance but distinct neurochemical effects of alprazolam and lorazepam.
    Psychopharmacology, 1993, Volume: 111, Issue:1

    Topics: Alprazolam; Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Down-Regulation; Drug Tolera

1993
Behavioural responsiveness to picrotoxin and desipramine in adult rats prenatally exposed to different benzodiazepine receptor agonists.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Alprazolam; Animals; Behavior, Animal; Desipramine; Diazepam; Female;

1995
The realities of clonazepam discontinuation.
    Psychiatric services (Washington, D.C.), 1997, Volume: 48, Issue:7

    Topics: Alprazolam; Anxiety Disorders; Benzodiazepines; Clonazepam; Drug Administration Schedule; GABA Modul

1997
Effect of alprazolam and ketamine on seizures induced by two different convulsants.
    Acta medica (Hradec Kralove), 1997, Volume: 40, Issue:1

    Topics: Alprazolam; Animals; Anticonvulsants; Aziridines; Convulsants; Ketamine; Male; Pentylenetetrazole; R

1997
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Apr-25, Volume: 97, Issue:9

    Topics: Acoustic Stimulation; Alprazolam; Animals; Anti-Anxiety Agents; Cognition; Conflict, Psychological;

2000
Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite.
    European journal of pharmacology, 2001, Volume: 415, Issue:2-3

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Azabicyclo Compounds; Diazepam;

2001
Chronic benzodiazepine administration. IX. Attenuation of alprazolam discontinuation effects by carbamazepine.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Alprazolam; Animals; Anxiety; Carbamazepine; Cerebral Cortex; Disease Models, Animal; Drug Administr

1991
Effect of alprazolam on pentylenetetrazol convulsions.
    Activitas nervosa superior, 1990, Volume: 32, Issue:4

    Topics: Alprazolam; Animals; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures

1990
Dependence-producing properties of alprazolam in the dog.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:3

    Topics: Administration, Oral; Alprazolam; Animals; Dogs; Dose-Response Relationship, Drug; Female; Flumazeni

1990
Alprazolam withdrawal.
    Texas medicine, 1990, Volume: 86, Issue:9

    Topics: Alprazolam; Coronary Disease; Female; Humans; Metoprolol; Seizures; Substance Withdrawal Syndrome

1990
Death following suspected alprazolam withdrawal seizures: a case report.
    Texas medicine, 1990, Volume: 86, Issue:1

    Topics: Alprazolam; Arrhythmias, Cardiac; Death, Sudden; Female; Humans; Middle Aged; Psychoses, Substance-I

1990
Alprazolam and withdrawal seizures.
    The Journal of nervous and mental disease, 1990, Volume: 178, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alprazolam; Female; Humans; Male; Middle Aged; Seizures;

1990
Seizures following the withdrawal of alprazolam.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:1

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Female; Humans; Panic; S

1986
Alprazolam dependence in seven patients.
    The American journal of psychiatry, 1988, Volume: 145, Issue:5

    Topics: Adult; Alcoholism; Alprazolam; Anxiety Disorders; Depressive Disorder; Female; Humans; Male; Marijua

1988
Triazolam withdrawal.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:9

    Topics: Alprazolam; Diazepam; Drug Tolerance; Humans; Seizures; Substance Withdrawal Syndrome; Triazolam

1988
Myoclonic seizures after abrupt withdrawal from phenelzine and alprazolam.
    The Journal of nervous and mental disease, 1987, Volume: 175, Issue:2

    Topics: Adult; Alprazolam; Drug Therapy, Combination; Female; Humans; Myoclonus; Phenelzine; Psychotic Disor

1987