alphaxalone has been researched along with Anesthesia in 97 studies
*Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (10.31) | 18.7374 |
| 1990's | 4 (4.12) | 18.2507 |
| 2000's | 7 (7.22) | 29.6817 |
| 2010's | 53 (54.64) | 24.3611 |
| 2020's | 23 (23.71) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, A; Boyd, AC; Byford, A; Campbell, AC; Gemmell, DK; Hamilton, NM; Hill, DR; Hill-Venning, C; Lambert, JJ; Maidment, MS; Marshall, RJ; May, V; Peters, JA; Rees, DC; Stevenson, D; Sundaram, H | 1 |
| Barboza, TK; Buck, RK; Dutton, C; Freitag, FA | 1 |
| Álvarez, ER; de Carellán Mateo, AG; Solé, LV | 1 |
| Crawford, A; Gustafson, D; Hasse, K; Johnston, M; Klaphake, E; Rao, S | 1 |
| Allavena, R; Farry, T; Goodwin, W; Keates, H; Lau, C; Pasloske, K; Woldeyohannes, S | 1 |
| Bellocchi, F; Bufalari, A; Giannettoni, G; Menchetti, L; Moretti, G; Nannarone, S; Pepe, A | 1 |
| Astleford, SM; Bowling, PA; Casselman, AM; Dixon, BC; Ghering, JM; Marion, BM; White, CE | 1 |
| Amsellem, P; Hamilton, S; Pan, PC; Savidge, C | 1 |
| Ahern, BJ; Cowling, N; Dhanani, J; Goodwin, W; Kat, I; Whitten, G | 1 |
| Allender, MC; Chinnadurai, SK; Fries, R; Kadotani, S; Keller, KA; Webb, JK | 1 |
| Ciotti-McClallen, M; Costa, RS; Maki, L; Perry, S; Starks, D; Stein, AB; Tilley, R | 1 |
| Chen, Y; Guo, Y; Li, Z; Liu, Q; Qing, M; Sheng, Y; Xie, L; Zhao, X; Zhou, Z | 1 |
| Chen, IY; Daimaruya, N; Itami, T; Sano, T; Sugita, C; Wei, Y; Yamashita, K | 2 |
| Gantner, L; Portier, K; Quintard, B | 1 |
| Clark-Price, S; Johnson, AK; Johnson, JA; Kemppainen, R; Trumble, J | 1 |
| Bisazza, KT; Easley, JT; Hess, AM; Lebsock, KJ; Mama, KR; Mangin, LM; Oakleaf, MH | 1 |
| Aarnes, TK; Bednarski, RM; Cremer, J; Lerche, P; Murdock, MA; Riccó Pereira, CH | 1 |
| Buck, RK; Dzikiti, BT; Fuller, A; Kamerman, P; Pohlin, F; Rioja, E; Zeiler, GE | 1 |
| Ishigami, A; Kaneko, A; Konoike, N; MacIntosh, AJJ; Miwa, M; Miyabe-Nishiwaki, T; Nakamura, K; Natsume, T | 1 |
| Ambar, N; Beaufrère, H; Eshar, D; Shrader, TC | 1 |
| Dupont, WD; Finnie, KR; Jones, CP; Salleng, KJ; Shuster, KA | 1 |
| Johns, TN; Lee, JC; Nunamaker, EA; West, SE | 1 |
| Hampton, CE; Liu, CC; Ross, JM; Takawira, C | 1 |
| Abelson, AL; Babyak, JM; Reader, RC; Yang, VK | 1 |
| Armstrong, T; Cheema, J; Pang, DS; Wagner, MC | 1 |
| de Vries, A; Deutsch, J; Ekiri, A | 1 |
| Bennett, RC; Raekallio, MR; Salla, KM; Scheinin, M; Vainio, OM | 1 |
| El-Hawari, SF; Endo, Y; Higuchi, C; Miyoshi, K; Oyama, N; Sakata, H; Sano, T; Suzuki, K; Tamura, J; Yamashita, K | 1 |
| Adami, C; d'Ovidio, D; Lanaro, E; Marino, F; Monticelli, P; Noviello, E | 1 |
| Hardie, RJ; Radkey, DI; Smith, LJ | 1 |
| Bertelsen, MF; James, LE; Wang, T; Williams, CJ | 1 |
| Sear, JW | 1 |
| Bradley, MP; Doerning, CM; Lester, PA; Nowland, MH | 2 |
| Doss, GA; Johnson, SM; Mans, C; Sladky, KK; Yaw, TJ | 1 |
| Caulkett, NA; Grenwich, L; Hancock, TM; Pajor, EA | 1 |
| Costa, GL; Ghidelli, A; Interlandi, CD; Leonardi, F; Musicò, M; Rosa, J | 1 |
| Blevins, CE; Erickson, RL; Marx, JO; Souza Dyer, C | 1 |
| da Cunha, A; Lagos-Carvajal, A; Liu, CC; Queiroz-Williams, P | 1 |
| Miyoshi, K; Ohsugi, T; Tsukamoto, Y; Yamada, N; Yamashita, K | 1 |
| Hampton, CE; Mandsager, RE; Riebold, TW | 1 |
| Dzikiti, BT; Labuscagne, S; Zeiler, GE | 1 |
| Bertelsen, MF; Hansen, LL | 1 |
| Braun, C; Divers, S; Hofmeister, EH; Shepard, MK | 1 |
| Drion, P; Sandersen, C; Serteyn, D; Sonea, A; Tutunaru, AC | 1 |
| Bettschart, R; Doebeli, A; Hartnack, S; Michel, E; Reichler, IM | 1 |
| Beths, T; Musk, G; Pasloske, K; Touzot-Jourde, G | 1 |
| Del Mar Granados, M; Fernández-Sarmiento, A; Gómez-Villamandos, RJ; López Villalba, I; Manuel Domínguez, J; Morgaz, J; Muñoz-Rascón, P; Navarrete-Calvo, R | 1 |
| Bettschart-Wolfensberger, R; Hässig, M; Jud, RS; Kalchofner Guerrero, KS; Reichler, IM; Schwarz, A | 1 |
| del Álamo, AM; Mandsager, RE; Payton, ME; Riebold, TW | 1 |
| Drynan, E; Hosgood, G; Raisis, AL; Smart, L | 1 |
| Knotek, Z | 1 |
| Huynh, M; Le Teuff, G; Pignon, C; Poumeyrol, S; Zilberstein, L | 1 |
| Bailey, KM; Griffith, EH; Harms, CA; Lewbart, GA; Minter, LJ; Posner, LP | 1 |
| Adami, C; Angeli, G; d'Ovidio, D; Spadavecchia, C | 1 |
| Amen, EM; Bergadano, A; Brecheisen, M; Casoni, D; Kuennecke, B; Müggler, T | 1 |
| Adami, C; Giovannini, AE; Imboden, T; Spadavecchia, C | 1 |
| Adami, C; Casoni, D; d'Ovidio, D | 1 |
| Goodchild, CS; Monagle, J; Serrao, JM; Siu, L; Worrell, J | 1 |
| Choi, R; Hyun, C; Lee, J; Suh, S | 1 |
| Bauquier, SH; Beths, T; Carter, JE; Warne, LN; Whittem, T | 1 |
| Choi, R; Hyun, C; Kim, YW; Suh, SI | 1 |
| Domínguez, JM; Férnandez-Sarmiento, JA; Funes, FJ; Gómez-Villamandos, RJ; Granados, Mdel M; Morgaz, J; Muñoz-Rascón, P; Navarrete, R; Quirós-Carmona, S | 1 |
| Fukui, S; Hatakeyama, N; Ishizuka, T; Itami, T; Miyoshi, K; Pasloske, K; Sano, T; Tamura, J; Yamashita, K | 1 |
| Bugman, AM; Hadzima, E; Langer, PT; Mitchell, MA; Rivas, AE | 1 |
| Broussaud, S; Khenissi, L; Nikolayenkova-Topie, O; Touzot-Jourde, G | 1 |
| Ayers, JD; Kendall, LV; Siriarchavatana, P | 1 |
| Harris, J; Hunt, J; Kelly, S; Knazovicky, D; Knowles, TG; Lascelles, BD; Murrell, J | 1 |
| Hashimoto, A; Higuchi, S; Miyoshi, K; Ohsugi, T; Yamada, R; Yamashita, K | 1 |
| Ansel, TV; Benavente-Perez, A; Nour, AK | 1 |
| Lerche, P; Muir, W; Nelson, L; Pasloske, K; Whittem, T; Wiese, A | 1 |
| Grint, NJ; Senior, JM; Smith, HE | 1 |
| Heit, MC; Pasloske, KS; Ranasinghe, MG; Whittem, T | 1 |
| Hansen, A; Maloney, SK; Marsh, MK; McLeod, SR | 1 |
| Roan, R | 1 |
| Pasloske, K; Perkins, N; Sauer, B; Whittem, T | 1 |
| Alibhai, HI; Armitage-Chan, E; Brodbelt, DC; Jimenez-Lozano, A; Psatha, E | 1 |
| Hall, WJ; Markos, F; Ruane-O'Hora, T | 1 |
| Bertelsen, MF; Sauer, CD | 1 |
| Beyerbach, M; Bösing, B; Kästner, SB; Mischke, R; Tünsmeyer, J | 1 |
| Bertelsen, MF; Duse, A; Kischinovsky, M; Wang, T | 1 |
| Herbert, GL; Murison, PJ | 1 |
| Keates, H | 1 |
| Howlett, JC; Jones, DM; Knight, JA; Samour, JH | 1 |
| Cookson, JH; Mills, FJ | 1 |
| Jackson, OF; Lawrence, K | 1 |
| Eales, FA; Small, J | 1 |
| Camburn, MA | 1 |
| Borthwick, N; Dick, H; Dow, RC; Fink, G; Malnick, S; Sarkar, DK; Twine, M | 1 |
| Payne, AR | 1 |
| Clark, WT; Colbourne, C; Cullen, LK; Goerke, MA; Nandapi, D; Swan, RA | 1 |
| Smith, W | 1 |
| Bennie, JG; Carroll, SM; Dow, RC; Fink, G; McQueen, JK | 1 |
| Ahmed, F; Lundin, LG; Shire, JG | 1 |
| Lögdberg, B | 1 |
| Gavin, JB; Sage, MD; West, EJ | 1 |
1 review(s) available for alphaxalone and Anesthesia
| Article | Year |
|---|---|
Challenges of bringing a new sedative to market!
Topics: Anesthesia; Benzodiazepines; Clinical Trials as Topic; Conscious Sedation; Drug Recalls; Humans; Hypnotics and Sedatives; Pregnanediones; Propofol | 2018 |
33 trial(s) available for alphaxalone and Anesthesia
| Article | Year |
|---|---|
Intramuscular alfaxalone with or without buprenorphine or hydromorphone provides sedation with minimal adverse effects in healthy rabbits (Oryctolagus cuniculus) in a randomized blinded controlled trial.
Topics: Anesthesia; Animals; Buprenorphine; Hydromorphone; Hypnotics and Sedatives; Injections, Intramuscular; Male; Pregnanediones; Rabbits | 2022 |
ED
Topics: Androstanols; Anesthesia; Animals; Dogs; Female; Male; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Prospective Studies; Rocuronium | 2023 |
Comparison of intravenous anesthetic induction doses and physiologic effects of ketamine or alfaxalone in goats undergoing surgery with isoflurane anesthesia.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Female; Goats; Heart Rate; Isoflurane; Ketamine; Midazolam; Pregnanediones; Prospective Studies; Random Allocation; Respiratory Rate; Single-Blind Method | 2019 |
Sedative and cardiorespiratory effects of intramuscular administration of alfaxalone and butorphanol combined with acepromazine, midazolam, or dexmedetomidine in dogs.
Topics: Acepromazine; Anesthesia; Anesthetics; Animals; Butorphanol; Cardiovascular System; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Dogs; Female; Heart Rate; Hypnotics and Sedatives; Injections, Intramuscular; Male; Midazolam; Pregnanediones | 2020 |
Development of a severity scoring system for acute haemorrhage in anaesthetized domestic cats: the CABSS score.
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Buprenorphine; Cat Diseases; Cats; Cross-Over Studies; Hemorrhage; Isoflurane; Pregnanediones; Severity of Illness Index | 2020 |
Anesthetic Effects of Intramuscular Alfaxalone-Ketamine in Naked Mole Rats (
Topics: Anesthesia; Animals; Drug Therapy, Combination; Female; Heart Rate; Ketamine; Laboratory Animal Science; Male; Mole Rats; Pregnanediones; Reflex; Respiratory Rate | 2020 |
A Comparison of the Efficacy and Cardiopulmonary Effects of 3 Different Sedation Protocols in
Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Anesthetics; Animals; Blood Pressure; Dexmedetomidine; Female; Galagidae; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Pregnanediones | 2020 |
Sedation Characteristics of Intranasal Alfaxalone in Adult Yucatan Swine.
Topics: Administration, Intranasal; Administration, Intravenous; Anesthesia; Anesthetics; Animals; Animals, Laboratory; Cross-Over Studies; Drug Administration Schedule; Pregnanediones; Prospective Studies; Swine | 2021 |
The effects of two intramuscular sedation protocols on echocardiographic variables in cats following sedation and blood donation.
Topics: Anesthesia; Animals; Blood Donors; Butorphanol; Cats; Conscious Sedation; Cross-Over Studies; Dexmedetomidine; Echocardiography; Female; Heart Rate; Heart Ventricles; Hypnotics and Sedatives; Injections, Intramuscular; Male; Pregnanediones | 2021 |
Alfaxalone for maintenance of anaesthesia in ponies undergoing field castration: continuous infusion compared with intravenous boluses.
Topics: Anesthesia; Anesthetics; Animals; Horses; Infusions, Intravenous; Injections, Intravenous; Male; Orchiectomy; Pregnanediones | 2017 |
Effects of the α
Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Cross-Over Studies; Dogs; Female; Infusions, Intravenous; Male; Medetomidine; Pregnanediones; Quinolizines; Receptors, Adrenergic | 2017 |
Sedative effects of intramuscular alfaxalone in pet guinea pigs (Cavia porcellus).
Topics: Anesthesia; Animals; Female; Guinea Pigs; Hypnotics and Sedatives; Male; Pets; Pregnanediones; Prospective Studies | 2018 |
Comparison of the effects of alfaxalone and propofol with acepromazine, butorphanol and/or doxapram on laryngeal motion and quality of examination in dogs.
Topics: Acepromazine; Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Butorphanol; Cross-Over Studies; Dog Diseases; Dogs; Doxapram; Female; Laryngoscopy; Larynx; Physical Examination; Pregnanediones; Propofol; Vocal Cord Paralysis | 2018 |
Effect of injection site on alfaxalone-induced sedation in ball pythons (Python regius).
Topics: Anesthesia; Anesthetics; Animals; Boidae; Cross-Over Studies; Female; Injections, Subcutaneous; Male; Pregnanediones; Prospective Studies; Random Allocation | 2018 |
An investigation of the effects of intratesticular alfaxalone and lidocaine during castration in piglets.
Topics: Anesthesia; Anesthetics; Animals; Drug Therapy, Combination; Lidocaine; Male; Orchiectomy; Pregnanediones; Swine; Testis | 2018 |
Immersion anaesthesia in goldfish (Carassius auratus) with three concentrations of alfaxalone.
Topics: Anesthesia; Anesthetics; Animals; Dose-Response Relationship, Drug; Goldfish; Immersion; Pregnanediones; Random Allocation; Treatment Outcome | 2019 |
Alfaxalone-Xylazine Anesthesia in Laboratory Mice (
Topics: Anesthesia; Anesthetics; Animals; Drug Therapy, Combination; Female; Ketamine; Laboratory Animal Science; Male; Mice; Mice, Inbred C57BL; Pregnanediones; Xylazine | 2019 |
Intramuscular Administration of Alfaxalone Alone and in Combination for Sedation and Anesthesia of Rabbits (
Topics: Anesthesia; Anesthetics; Animals; Butorphanol; Cross-Over Studies; Dexmedetomidine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Injections, Intramuscular; Laboratory Animal Science; Midazolam; Pregnanediones; Rabbits | 2019 |
Determination of midazolam dose for co-induction with alfaxalone in sedated cats.
Topics: Anesthesia; Anesthetics, Combined; Animals; Cats; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Intubation, Intratracheal; Male; Midazolam; Pregnanediones; Random Allocation | 2019 |
Recovery characteristics of dogs following anesthesia induced with tiletamine-zolazepam, alfaxalone, ketamine-diazepam, or propofol and maintained with isoflurane.
Topics: Anesthesia; Animals; Cross-Over Studies; Diazepam; Dogs; Heart Rate; Isoflurane; Ketamine; Pregnanediones; Propofol; Prospective Studies; Reproducibility of Results; Retrospective Studies; Tiletamine; Zolazepam | 2019 |
Effects of chemical and mechanical stimulation on laryngeal motion during alfaxalone, thiopentone or propofol anaesthesia in healthy dogs.
Topics: Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dog Diseases; Dogs; Larynx; Pregnanediones; Propofol; Random Allocation; Thiopental; Vocal Cord Paralysis | 2019 |
Evaluation of intravenous administration of alfaxalone, propofol, and ketamine-diazepam for anesthesia in alpacas.
Topics: Anesthesia; Anesthetics; Animals; Camelids, New World; Diazepam; Drug Therapy, Combination; Female; Injections, Intravenous; Ketamine; Male; Pregnanediones; Propofol | 2015 |
Cardiovascular function during maintenance of anaesthesia with isoflurane or alfaxalone infusion in greyhounds experiencing blood loss.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Loss, Surgical; Cardiovascular Physiological Phenomena; Dog Diseases; Dogs; Female; Infusions, Intravenous; Isoflurane; Male; Pregnanediones | 2015 |
Intramuscular administration of alfaxalone for sedation in rabbits.
Topics: Anesthesia; Anesthetics; Animals; Cross-Over Studies; Dose-Response Relationship, Drug; Injections, Intramuscular; Male; Pregnanediones; Rabbits | 2015 |
Alfaxalone as an intramuscular injectable anesthetic in koi carp (Cyprinus carpio).
Topics: Anesthesia; Anesthetics; Animals; Carps; Dose-Response Relationship, Drug; Injections, Intramuscular; Pregnanediones | 2014 |
Combinations of dexmedetomidine and alfaxalone with butorphanol in cats: application of an innovative stepwise optimisation method to identify optimal clinical doses for intramuscular anaesthesia.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Animals; Butorphanol; Cats; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Injections, Intramuscular; Male; Pregnanediones; Prospective Studies; Treatment Outcome | 2016 |
Alfaxalone versus alfaxalone-dexmedetomidine anaesthesia by immersion in oriental fire-bellied toads (Bombina orientalis).
Topics: Anesthesia; Anesthetics, Combined; Animals; Anura; Dexmedetomidine; Pilot Projects; Pregnanediones; Prospective Studies | 2016 |
A Phase 1c Trial Comparing the Efficacy and Safety of a New Aqueous Formulation of Alphaxalone with Propofol.
Topics: Adolescent; Adult; Anesthesia; Anesthetics, Intravenous; Blood Pressure; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedatives; Male; Pregnanediones; Propofol; Water; Young Adult | 2015 |
Comparison of intramuscular alfaxalone and ketamine combined with dexmedetomidine and butorphanol for castration in cats.
Topics: Anesthesia; Anesthetics, Combined; Animals; Blood Pressure; Butorphanol; Cats; Dexmedetomidine; Heart Rate; Injections, Intramuscular; Ketamine; Male; Orchiectomy; Pain Measurement; Pain, Postoperative; Pregnanediones; Prospective Studies; Treatment Outcome | 2017 |
Cardiorespiratory and anesthetic effects of clinical and supraclinical doses of alfaxalone in dogs.
Topics: Anesthesia; Anesthetics; Animals; Cross-Over Studies; Dogs; Dose-Response Relationship, Drug; Female; Male; Pregnanediones | 2008 |
Clinical evaluation of alfaxalone in cyclodextrin for the induction of anaesthesia in rabbits.
Topics: Anesthesia; Anesthetics; Animals; Cyclodextrins; Dose-Response Relationship, Drug; Pilot Projects; Pregnanediones; Rabbits | 2008 |
Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Blood Pressure; Body Temperature; Diazepam; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Fentanyl; Heart Rate; Male; Preanesthetic Medication; Pregnanediones; Respiration | 2011 |
Intramuscular administration of alfaxalone in red-eared sliders (Trachemys scripta elegans)--effects of dose and body temperature.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Pregnanediones; Turtles | 2013 |
63 other study(ies) available for alphaxalone and Anesthesia
| Article | Year |
|---|---|
Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors.
Topics: Anesthesia; Anesthetics; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cell Membrane; Chromaffin System; Electric Conductivity; Electrophysiology; Male; Mice; Molecular Structure; Morpholines; Pregnanediones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solubility; Structure-Activity Relationship; Water | 1997 |
Alfaxalone for anesthesia of a giant snake.
Topics: Anesthesia; Anesthetics; Animals; Pregnanediones; Snakes | 2022 |
Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups.
Topics: Anesthesia; Animals; Female; Guinea Pigs; Humans; Hypnotics and Sedatives; Male; Midazolam; Pregnanediones | 2022 |
PLASMA CONCENTRATION AND PHARMACODYNAMICS OF INTRAMUSCULAR ADMINISTRATION OF ALFAXALONE IN INDIAN PEAFOWL (
Topics: Anesthesia; Anesthetics; Animals; Female; Injections, Intramuscular; Pregnanediones | 2022 |
Comparison of two formulations of alfaxalone for immersion anaesthesia in laboratory zebrafish (Daniorerio).
Topics: Anesthesia; Anesthetics; Animals; Female; Immersion; Male; Pregnanediones; Prospective Studies; Water; Zebrafish | 2022 |
Sedation quality of alfaxalone associated with butorphanol, methadone or pethidine in cats injected into the supraspinatus or the quadriceps muscle.
Topics: Anesthesia; Animals; Butorphanol; Cat Diseases; Cats; Hypnotics and Sedatives; Injections, Intramuscular; Meperidine; Methadone; Mydriasis; Pregnanediones; Quadriceps Muscle; Rotator Cuff | 2022 |
Comparison of Alfaxalone-Midazolam, Tiletamine-Zolazepam, and KetamineAcepromazine Anesthesia during Plethysmography in Cynomolgus Macaques (
Topics: Acepromazine; Anesthesia; Anesthetics; Animals; Drug Combinations; Ketamine; Macaca fascicularis; Macaca mulatta; Midazolam; Plethysmography; Pregnanediones; Tiletamine; Zolazepam | 2022 |
Comparison between propofol and alfaxalone anesthesia for the evaluation of laryngeal function in healthy dogs utilizing computerized software.
Topics: Anesthesia; Anesthetics; Animals; Dogs; Female; Male; Pregnanediones; Propofol; Software; Vocal Cord Paralysis | 2022 |
Long duration anaesthesia in pigs with an infusion of alfaxalone and dexmedetomidine.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Dexmedetomidine; Pregnanediones; Swine | 2022 |
Use of alfaxalone in bearded dragons (Pogona vitticeps): optimizing pharmacodynamics and evaluating cardiogenic effects via echocardiography.
Topics: Anesthesia; Animals; Cross-Over Studies; Echocardiography; Lizards; Pregnanediones | 2022 |
Alfaxalone Alleviates Neurotoxicity and Cognitive Impairment Induced by Isoflurane Anesthesia in Offspring Rats.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cognitive Dysfunction; Cytokines; Female; Hippocampus; Isoflurane; Maze Learning; Pregnancy; Rats; Rats, Sprague-Dawley; Synaptophysin | 2023 |
Comparison of intramuscular alfaxalone with medetomidine-ketamine for inducing anaesthesia in Trachemys scripta spp. undergoing sterilization.
Topics: Anesthesia; Anesthetics; Animals; Female; Injections, Intramuscular; Ketamine; Medetomidine; Prospective Studies; Sterilization; Turtles | 2023 |
Sugammadex for reversal of rocuronium-induced neuromuscular blockade during alfaxalone anesthesia in dogs.
Topics: Anesthesia; Anesthetics; Animals; Cross-Over Studies; Dogs; Female; Male; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Prospective Studies; Rocuronium; Sugammadex | 2023 |
Alfaxalone increases measured progesterone concentration in neutered male cats when determined by immunoreactivity.
Topics: Anesthesia; Anesthetics; Animals; Cats; Male; Pregnanediones; Progesterone | 2023 |
Evaluation of anaesthetic and cardiorespiratory effects after intramuscular administration of alfaxalone alone, alfaxalone-ketamine and alfaxalone-butorphanol-medetomidine in common marmosets (Callithrix jacchus).
Topics: Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Callithrix; Female; Heart Rate; Injections, Intramuscular; Ketamine; Medetomidine; Pregnanediones | 2020 |
Intraperitoneal Alfaxalone and Alfaxalone-Dexmedetomidine Anesthesia in Sprague-Dawley Rats (
Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Laboratory Animal Science; Male; Pregnanediones; Rats; Rats, Sprague-Dawley; Respiratory Rate | 2020 |
Assessing analgesia equivalence and appetite following alfaxalone- or ketamine-based injectable anesthesia for feline castration as an example of enhanced recovery after surgery.
Topics: Analgesia; Analgesics; Anesthesia; Anesthetics; Animals; Cats; Dexmedetomidine; Feeding Behavior; Hydromorphone; Ketamine; Male; Orchiectomy; Pain Measurement; Pain, Postoperative; Postoperative Care; Pregnanediones; Random Allocation | 2018 |
Anesthetic and cardiorespiratory effects of single-bolus intravenous alfaxalone with or without intramuscular xylazine-premedication in calves.
Topics: Anesthesia; Anesthesia, Intravenous; Animals; Blood Pressure; Carbon Dioxide; Cattle; Female; Heart Rate; Intubation, Intratracheal; Male; Oxygen; Pregnanediones; Premedication; Xylazine | 2018 |
Anaesthetic induction with alfaxalone in the ball python (Python regius): dose response and effect of injection site.
Topics: Anesthesia; Anesthetics; Animals; Boidae; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Pregnanediones | 2018 |
Effects of subcutaneous alfaxalone alone and in combination with dexmedetomidine and buprenorphine in guinea pigs (Cavia porcellus).
Topics: Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Buprenorphine; Dexmedetomidine; Female; Guinea Pigs; Injections, Subcutaneous; Pregnanediones | 2018 |
Anesthetic effect of a mixture of alfaxalone, medetomidine, and butorphanol for inducing surgical anesthesia in ICR, BALB/c, and C57BL/6 mouse strains.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Body Temperature; Butorphanol; Injections, Subcutaneous; Medetomidine; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Pregnanediones; Specific Pathogen-Free Organisms | 2019 |
Assessment of the effects of intramuscular administration of alfaxalone with and without medetomidine in Horsfield's tortoises (Agrionemys horsfieldii).
Topics: Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Hypnotics and Sedatives; Injections, Intramuscular; Male; Medetomidine; Pregnanediones; Turtles | 2013 |
Pharmacodynamics of alfaxalone after single-dose intramuscular administration in red-eared sliders (Trachemys scripta elegans): a comparison of two different doses at two different ambient temperatures.
Topics: Anesthesia; Anesthetics; Animals; Blinking; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intramuscular; Muscle Relaxation; Nociception; Pregnanediones; Temperature; Turtles | 2013 |
Anaesthetic induction with alfaxalone may produce hypoxemia in rabbits premedicated with fentanyl/droperidol.
Topics: Adjuvants, Anesthesia; Administration, Intravenous; Anesthesia; Anesthetics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Droperidol; Female; Fentanyl; Heart Rate; Hypoxia; Preanesthetic Medication; Pregnanediones; Rabbits; Respiratory Rate | 2013 |
Apgar score after induction of anesthesia for canine cesarean section with alfaxalone versus propofol.
Topics: Anesthesia; Animals; Animals, Newborn; Cesarean Section; Dogs; Female; Pregnancy; Pregnanediones; Propofol | 2013 |
Clinical evaluation of alfaxalone to induce and maintain anaesthesia in cats undergoing neutering procedures.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Animals; Blood Gas Analysis; Cat Diseases; Cats; Female; Heart Rate; Male; Monitoring, Intraoperative; Pregnanediones; Respiration; Respiratory Rate; Treatment Outcome | 2014 |
Cardiorespiratory, anaesthetic and recovery effects of morphine combined with medetomidine and alfaxalone in rabbits.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Animals; Blood Gas Analysis; Blood Pressure; Cross-Over Studies; Female; Injections, Intramuscular; Medetomidine; Morphine; Pregnanediones; Rabbits; Respiration; Respiratory Rate | 2014 |
Alfaxalone or ketamine-medetomidine in cats undergoing ovariohysterectomy: a comparison of intra-operative parameters and post-operative pain.
Topics: Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Cats; Female; Hysterectomy; Intraoperative Period; Ketamine; Medetomidine; Ovariectomy; Pain Measurement; Pain, Postoperative; Pregnanediones | 2014 |
Alfaxalone as an induction agent for anaesthesia in terrapins and tortoises.
Topics: Anesthesia; Anesthetics; Animals; Female; Preanesthetic Medication; Pregnanediones; Treatment Outcome; Turtles | 2014 |
Alfaxalone anesthesia by immersion in oriental fire-bellied toads (Bombina orientalis).
Topics: Anesthesia; Anesthetics; Animals; Anura; Immersion; Pregnanediones; Prospective Studies; Time Factors; Treatment Outcome | 2015 |
A combination of alfaxalone and medetomidine followed by an alfaxalone continuous rate infusion in cynomolgus monkeys (Macaca fascicularis) undergoing pharmacoMRS.
Topics: Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Heart Rate; Infusion Pumps; Infusions, Intravenous; Injections, Intramuscular; Macaca fascicularis; Magnetic Resonance Spectroscopy; Male; Medetomidine; Pregnanediones; Respiration; Treatment Outcome | 2015 |
Cardiorespiratory and anesthetic effects produced by the combination of butorphanol, medetomidine and alfaxalone administered intramuscularly in Beagle dogs.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics; Animals; Butorphanol; Dogs; Drug Combinations; Heart Rate; Hypnotics and Sedatives; Injections, Intramuscular; Medetomidine; Pregnanediones; Respiration | 2016 |
Influence of two administration rates of alfaxalone at induction on its relative potency in cats: a pilot study.
Topics: Anesthesia; Anesthesia Recovery Period; Animals; Cat Diseases; Cats; Female; Hysterectomy; Ovariectomy; Pilot Projects; Pregnanediones; Respiration; Treatment Outcome | 2017 |
Evaluation of quality of anesthesia and analgesia and of vital signs after intramuscular administration of a combination of butorphanol, medetomidine and alfaxalone in cats.
Topics: Analgesia; Analgesics, Opioid; Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Cats; Female; Male; Medetomidine; Pregnanediones | 2016 |
Effect of dexmedetomidine constant rate infusion on the bispectral index during alfaxalone anaesthesia in dogs.
Topics: Anesthesia; Anesthetics; Animals; Consciousness; Dexmedetomidine; Dogs; Electroencephalography; Electromyography; Female; Heart Rate; Male; Pain Measurement; Pregnanediones; Prospective Studies | 2016 |
The pharmacological effects of intramuscular administration of alfaxalone combined with medetomidine and butorphanol in dogs.
Topics: Anesthesia; Anesthetics, Combined; Animals; Blood Pressure; Body Temperature; Butorphanol; Dogs; Electrocardiography; Female; Heart Rate; Injections, Intramuscular; Male; Medetomidine; Pregnanediones; Respiratory Rate | 2016 |
Evaluation of the anesthetic efficacy of alfaxalone in oscar fish (Astronotus ocellatus).
Topics: Anesthesia; Anesthetics; Animals; Blood Gas Analysis; Carbon Dioxide; Fishes; Heart Rate; Immersion; Lactates; Pregnanediones | 2016 |
Anesthetic Activity of Alfaxalone Compared with Ketamine in Mice.
Topics: Anesthesia; Anesthetics; Animals; Body Temperature; Cross-Over Studies; Drug Combinations; Female; Ketamine; Male; Mice; Mice, Inbred C57BL; Pregnanediones; Random Allocation; Reflex; Xylazine | 2016 |
Alfaxalone Anaesthesia Facilitates Electrophysiological Recordings of Nociceptive Withdrawal Reflexes in Dogs (Canis familiaris).
Topics: Anesthesia; Anesthetics; Animals; Consciousness; Dogs; Electrophysiological Phenomena; Male; Osteoarthritis; Pain; Pregnanediones; Reflex | 2016 |
Evaluation of a combination of alfaxalone with medetomidine and butorphanol for inducing surgical anesthesia in laboratory mice.
Topics: Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Butorphanol; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Medetomidine; Mice; Mice, Inbred ICR; Pregnanediones; Random Allocation; Specific Pathogen-Free Organisms | 2016 |
The Effect of Anesthesia on Blood Pressure Measured Noninvasively by Using the Tail-Cuff Method in Marmosets (Callithrix jacchus).
Topics: Anesthesia; Anesthetics; Animals; Blood Pressure; Blood Pressure Determination; Callithrix; Female; Humans; Male; Pregnanediones; Reproducibility of Results; Tail | 2016 |
The pharmacokinetics and pharmacodynamics of alfaxalone in cats after single and multiple intravenous administration of Alfaxan at clinical and supraclinical doses.
Topics: Anesthesia; Anesthetics; Animals; Area Under Curve; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Half-Life; Injections, Intravenous; Linear Models; Male; Models, Theoretical; Pregnanediones | 2008 |
Induction of anaesthesia in wild rabbits using a new alfaxalone formulation.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Animals, Wild; Australia; Drug Combinations; Female; Hypnotics and Sedatives; Male; Medetomidine; Pregnanediones; Rabbits; Treatment Outcome | 2009 |
Use of alfaxalone in rabbits.
Topics: Anesthesia; Anesthetics; Animals; Cats; Clinical Trials as Topic; Dogs; Drug Approval; Pregnanediones; Rabbits; United Kingdom | 2009 |
Plasma pharmacokinetics of alfaxalone in both premedicated and unpremedicated Greyhound dogs after single, intravenous administration of Alfaxan at a clinical dose.
Topics: Acepromazine; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Animals; Dogs; Female; Injections, Intravenous; Male; Morphine; Preanesthetic Medication; Pregnanediones | 2009 |
The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig.
Topics: Adrenocorticotropic Hormone; Anesthesia; Anesthetics; Animals; beta-Endorphin; Blood Pressure; Heart Rate; Hemorrhage; Hypovolemia; Pentobarbital; Pregnanediones; Propofol; Swine | 2011 |
Alfaxalone anaesthesia in the green iguana (Iguana iguana).
Topics: Anesthesia; Anesthetics; Animals; Dose-Response Relationship, Drug; Heart Rate; Iguanas; Injections, Intramuscular; Pregnanediones; Respiratory Rate; Time Factors | 2011 |
[Clinical usability and practicability of Alfaxalone for short-term anaesthesia in the cat after premedication with Buprenorphine].
Topics: Analgesics, Opioid; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Blood Chemical Analysis; Blood Gas Analysis; Blood Pressure; Buprenorphine; Cats; Female; Heart Rate; Hematologic Tests; Injections, Intravenous; Male; Preanesthetic Medication; Pregnanediones; Respiration; Time Factors | 2012 |
Eye position of cats anaesthetised with alfaxalone or propofol.
Topics: Anesthesia; Anesthetics; Animals; Cats; Female; Male; Ocular Physiological Phenomena; Pregnanediones; Propofol | 2013 |
Induction of anaesthesia in pigs using a new alphaxalone formulation.
Topics: Anesthesia; Anesthetics; Animals; Azaperone; Embryo Implantation; Female; Heart Rate; Injections, Intravenous; Pregnanediones; Swine | 2003 |
Comparative studies of the use of some injectable anaesthetic agents in birds.
Topics: Anesthesia; Anesthetics; Animals; Animals, Zoo; Birds; Drug Combinations; Female; Immobilization; Injections, Intramuscular; Injections, Intravenous; Ketamine; Male; Pregnanediones; Xylazine | 1984 |
Continuous infusion anaesthesia in baboons with alphaxolone-alphadolone.
Topics: Anesthesia; Animals; Animals, Laboratory; Infusions, Parenteral; Papio; Pregnanediones | 1983 |
Alphaxalone/alphadolone anaesthesia in reptiles.
Topics: Anesthesia; Anesthetics; Animals; Pregnanediones; Reptiles; Surgery, Veterinary | 1983 |
Alphaxalone/alphadolone anaesthesia in the lamb.
Topics: Anesthesia; Anesthetics; Animals; Animals, Newborn; Drug Combinations; Heart Rate; Pregnanediones; Respiration; Sheep | 1982 |
Use of alphaxalone-alphadolone in ruminants.
Topics: Anesthesia; Animals; Cattle; Drug Combinations; Goats; Injections, Intravenous; Pregnanediones; Rumen; Sheep | 1982 |
Sex difference in response to alphaxalone anaesthesia may be oestrogen dependent.
Topics: Age Factors; Alfaxalone Alfadolone Mixture; Anesthesia; Animals; Castration; Electroencephalography; Estrogens; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Pregnanediones; Promegestone; Rats; Sex Characteristics | 1982 |
Use of Saffan in dogs.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia; Anesthetics; Animals; Dogs; Pregnanediones | 1981 |
Ostrich anaesthesia: xylazine premedication followed by alphaxalone/alphadolone and isoflurane.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Birds; Drug Therapy, Combination; Isoflurane; Preanesthetic Medication; Pregnanediones; Xylazine | 1995 |
Responses of laboratory animals to some injectable anaesthetics.
Topics: Anesthesia; Anesthetics; Animals; Animals, Laboratory; Female; Injections, Intramuscular; Injections, Intraperitoneal; Injections, Intravenous; Ketamine; Male; Methohexital; Pregnanediones; Xylazine | 1993 |
Serotonergic 5-HT2A receptors important for the oestradiol-induced surge of luteinising hormone-releasing hormone in the rat.
Topics: Anesthesia; Anesthetics; Animals; Cyclic S-Oxides; Diestrus; Estradiol; Female; Fluoxetine; Gonadotropin-Releasing Hormone; Ketanserin; Naphthalenes; Ovariectomy; Pituitary Gland; Pregnanediones; Proestrus; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 1999 |
Lysosomal mutations increase susceptibility to anaesthetics.
Topics: Anesthesia; Anesthetics; Animals; Ethanol; Female; Homozygote; Lysosomes; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Pentobarbital; Pigmentation; Pregnanediones; Time Factors | 1989 |
Alphaxolone-alphadolone for anesthesia of squirrel monkeys of different ages.
Topics: Age Factors; Anesthesia; Anesthetics; Animals; Body Temperature; Cebidae; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Pregnanediones; Reference Values; Respiration; Saimiri | 1988 |
Cardiac performance of isolated beating hearts obtained from rats anesthetized by three different agents.
Topics: Anesthesia; Animals; Coronary Circulation; Ether; Ethyl Ethers; Heart; Heart Rate; Pentobarbital; Pregnanediones; Rats | 1985 |