alphadolone has been researched along with Drug-Hypersensitivity* in 3 studies
3 other study(ies) available for alphadolone and Drug-Hypersensitivity
| Article | Year |
|---|---|
Allergic reactions to intravenous anaesthetic induction agents and muscle relaxants. Case reports and a clinical review.
Allergic reactions to the intravenous drugs used in anaesthesia pose a major problem for the anaesthetist, since they represent an unpredictable and occasionally life-threatening event. Reports of 2 such cases are presented, and the incidence, assessment and prophylaxis of such reactions are discussed. Topics: Alcuronium; Anesthesia, Intravenous; Anesthetics; Child; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Pregnanediones; Toxiferine | 1985 |
Adjuvancy of Cremophor Elo in rodents.
Cremophor Elo proved as potent as Freund's complete adjuvant for eliciting skin reactivity to bovine serum albumin in guinea pigs. It enhanced delayed hypersensitivity to sheep erythrocytes in mice while hemagglutinin antibody titers were not affected. This adjuvant activity is likely to play a critical role in hypersensitivity reactions to Cremophor-containing drugs, e.g. alphadione. Topics: Adjuvants, Immunologic; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pregnanediones; Serum Albumin, Bovine | 1983 |
Assessment of the allergenic potential of althesin and its constituents.
The pharmaceutical formulation of Althesin was shown to have a weak allergenic potential in the guinea pig maximization test. Alphadolone and alphaxalone acetate were found to be devoid of such potential, while the status of Cremophor EL remained equivocal. Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Intradermal Tests; Male; Pregnanediones | 1983 |