alpha-synuclein has been researched along with Latent-Infection* in 1 studies
1 review(s) available for alpha-synuclein and Latent-Infection
| Article | Year |
|---|---|
How microcompetition with latent viruses can cause α synuclein aggregation, mitochondrial dysfunction, and eventually Parkinson's disease.
The cause of most Parkinson's disease cases is unknown. However, it is well documented that mitochondrial dysfunction and misfolded α synuclein aggregation are important cellular abnormalities associated with the disease. In this paper, we use the microcompetition model to show how latent viruses, which infect the central and peripheral nervous systems, can cause the observed mitochondrial dysfunction and excess α synuclein aggregation, and eventually, Parkinson's disease. Topics: alpha-Synuclein; Animals; Humans; Latent Infection; Mitochondria; Parkinson Disease; Protein Aggregation, Pathological; Virus Latency; Viruses | 2021 |