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alpha-naphthoflavone and Experimental Hepatoma

alpha-naphthoflavone has been researched along with Experimental Hepatoma in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's7 (38.89)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asamoto, M; Doi, Y; Naiki-Ito, A; Shirai, T; Suzuki, S; Takahashi, S; Takeshita, K1
Beltrán-Ramírez, O; Pérez, RM; Sierra-Santoyo, A; Villa-Treviño, S1
Cai, Y; Gong, LK; Liu, LL; Qi, XM; Ren, J; Wang, H; Wu, XF; Xiao, Y1
Chun, YJ; Chung, JY; Hong, YP; Kim, JM; Kim, JY; Kim, WR; Kim, YJ; Lee, SG; Oh, S; Park, JE; Park, YC; Yoo, KS; Yoo, YH1
Li, JJ; Li, SA3
Perdew, GH; Swanson, HI1
Cheek, JM; Denison, MS; Gebremichael, A; Pinkerton, KE; Tullis, K1
Alexander, D; Bailey, G; Baird, W; Harttig, U; Hendricks, J; Miller, MR; Reddy, AP; Stamm, SC; Weimer, TL1
Merchant, M; Morrison, V; Safe, S; Santostefano, M1
Gonzalez, A; Li, JJ; Li, SA; Oberley, TD; Slattery, AF1
Gladek, A; Liehr, JG; Macatee, T; Randerath, E; Randerath, K1
Arellano, L; Merchant, M; Safe, S1
Blaich, G; Metzler, M; Tritscher, AM1
Metzler, M; Tritscher, AM1
Blaich, G; Metzler, M1
Bassi, AM; Ferro, M; Marinari, UM; Nanni, G1

Reviews

1 review(s) available for alpha-naphthoflavone and Experimental Hepatoma

ArticleYear
Role of metabolic activation in the carcinogenicity of estrogens: studies in an animal liver tumor model.
    Environmental health perspectives, 1990, Volume: 88

    Topics: Animals; Benzoflavones; Biotransformation; Cricetinae; Diethylstilbestrol; Estrogens; Ethinyl Estradiol; In Vitro Techniques; Liver Neoplasms, Experimental; Male; Mesocricetus; Microsomes, Liver

1990

Other Studies

17 other study(ies) available for alpha-naphthoflavone and Experimental Hepatoma

ArticleYear
2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis is not enhanced by CYP1A inducers, alpha- and beta-naphthoflavone: relationship to intralobular distribution of CYP1A expression.
    Toxicologic pathology, 2010, Volume: 38, Issue:4

    Topics: Analysis of Variance; Animals; Arylamine N-Acetyltransferase; Benzoflavones; beta-Naphthoflavone; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochromes; Drug Synergism; Enzyme Inhibitors; Immunohistochemistry; Isoenzymes; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Organ Specificity; Quinoxalines; Rats; Rats, Inbred F344

2010
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
    Toxicologic pathology, 2012, Volume: 40, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Caffeic Acids; Carcinogenicity Tests; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochromes; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms, Experimental; Male; Phenylethyl Alcohol; Proadifen; Rats; Rats, Inbred F344; Steroid Hydroxylases

2012
Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; Carcinogens; Cocarcinogenesis; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Diethylnitrosamine; Ditiocarb; Liver Neoplasms, Experimental; Male; Malondialdehyde; Microsomes, Liver; Rats; Rats, Sprague-Dawley

2005
Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.
    Toxicology, 2007, Jun-03, Volume: 235, Issue:1-2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Benzoflavones; Carcinogens; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Down-Regulation; Ellipticines; Enzyme Induction; Enzyme Inhibitors; Liver Neoplasms, Experimental; Mice; Phosphorylation; Receptors, Aryl Hydrocarbon; Tumor Suppressor Protein p53

2007
High incidence of hepatocellular carcinomas after synthetic estrogen administration in Syrian golden hamsters fed alpha-naphthoflavone: a new tumor model.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:2

    Topics: Animals; Benzoflavones; Cricetinae; Diethylstilbestrol; Disease Models, Animal; Estradiol Congeners; Ethinyl Estradiol; Flavonoids; Hexestrol; Kidney Neoplasms; Liver Neoplasms, Experimental; Mesocricetus; Progesterone; Time Factors

1984
Estrogen-induced tumorigenesis in hamsters: roles for hormonal and carcinogenic activities.
    Archives of toxicology, 1984, Volume: 55, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cricetinae; Estrogen Antagonists; Estrogens; Glutathione Transferase; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Peroxidases; Receptors, Progesterone; Structure-Activity Relationship

1984
Changes in estrogen receptor levels during DES-induced hepatocarcinogenesis in the Syrian hamster fed alpha-naphthoflavone.
    Journal of steroid biochemistry, 1981, Volume: 15

    Topics: Animals; Benzoflavones; Cell Nucleus; Cocarcinogenesis; Cricetinae; Cytosol; Diethylstilbestrol; Estradiol; Female; Flavonoids; Liver Neoplasms, Experimental; Male; Mesocricetus; Receptors, Estrogen

1981
Half-life of aryl hydrocarbon receptor in Hepa 1 cells: evidence for ligand-dependent alterations in cytosolic receptor levels.
    Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Nucleus; Cytosol; Half-Life; Ligands; Liver Neoplasms, Experimental; Mice; Receptors, Aryl Hydrocarbon; Receptors, Drug; Tumor Cells, Cultured

1993
Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke.
    Toxicology and applied pharmacology, 1996, Volume: 141, Issue:1

    Topics: Animals; Benzoflavones; Cells, Cultured; Cryoprotective Agents; Cytochrome P-450 CYP1A1; Dimethyl Sulfoxide; Gene Expression; Liver Neoplasms, Experimental; Luciferases; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Tobacco Smoke Pollution

1996
Influence of beta-naphthoflavone on 7,12-dimethylbenz(a)anthracene metabolism, DNA adduction, and tumorigenicity in rainbow trout.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cells, Cultured; Cytochrome P-450 CYP1A1; Diet; DNA Adducts; DNA Damage; DNA Repair; Drug Interactions; Enzyme Inhibitors; Liver; Liver Neoplasms, Experimental; Mice; Microsomes, Liver; Oncorhynchus mykiss

2000
Mechanism of action of aryl hydrocarbon receptor antagonists: inhibition of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.
    Archives of biochemistry and biophysics, 1992, Nov-01, Volume: 298, Issue:2

    Topics: Animals; Base Sequence; Benzoflavones; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Gene Expression; Humans; Kinetics; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidoreductases; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1992
Comparative morphologic and immunohistochemical studies of estrogen plus alpha-naphthoflavone-induced liver tumors in Syrian hamsters and rats.
    The American journal of pathology, 1991, Volume: 139, Issue:3

    Topics: Animals; Benzoflavones; Cricetinae; Drug Combinations; Ethinyl Estradiol; Immunoenzyme Techniques; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus; Rats; Rats, Inbred Strains

1991
DNA adduct formation in liver and kidney of male Syrian hamsters treated with estrogen and/or alpha-naphthoflavone.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: Animals; Benzoflavones; Cricetinae; Diethylstilbestrol; DNA; DNA Adducts; Drug Interactions; Drug Synergism; Estrogens; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Male; Mesocricetus

1991
The mechanism of action of alpha-naphthoflavone as an inhibitor of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced CYP1A1 gene expression.
    Archives of biochemistry and biophysics, 1990, Aug-15, Volume: 281, Issue:1

    Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dioxins; Drug Interactions; Enzyme Induction; Flavonoids; Gene Expression; Hydrocarbons; Liver Neoplasms, Experimental; Oxidoreductases; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Receptors, Drug; Transcription, Genetic; Tumor Cells, Cultured

1990
Modulation of 17 alpha-ethinylestradiol and 7,8-benzoflavone metabolism in hamster liver microsomes is possibly related to hepatotumorigenesis.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Animals; Benzoflavones; Carcinogens; Cricetinae; Ethinyl Estradiol; Flavonoids; In Vitro Techniques; Liver Neoplasms, Experimental; Male; Mesocricetus; Microsomes, Liver

1989
Effect of pretreatment of male Syrian golden hamsters with 7,8-benzoflavone and with diethylstilbestrol on P-450 isoenzyme activities and on microsomal diethylstilbestrol metabolism.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:6

    Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Cocarcinogenesis; Cricetinae; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Diethylstilbestrol; Flavonoids; Isoenzymes; Liver Neoplasms, Experimental; Male; Mesocricetus; Microsomes, Liver

1988
Biochemical properties of carcinogen-metabolizing enzymes in cultured hepatoma cells.
    Toxicologic pathology, 1987, Volume: 15, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cell Line; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Liver Neoplasms, Experimental; Metyrapone; Protein Biosynthesis; Rats

1987