alpha-naphthoflavone has been researched along with Breast Cancer in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Muftuoglu, Y; Mustata, G | 1 |
| Cheng, M; Qin, Q; Sun, Y; Wang, J; Wang, L; Wu, T; Xue, Y; Yang, H; Yin, W; Zhao, D | 1 |
| Barrow, D; Eissa, AG; Foster, PA; Gee, J; Powell, LE; Simons, C | 1 |
| Ankrett, DN; Arroo, RRJ; Beresford, KJM; Bhambra, AS; Butler, PC; Ijaz, T; Lodhi, S; Potter, GA; Ruparelia, KC; Tan, HL; Wilsher, NE; Zeka, K | 1 |
| Abd Elmageed, ZY; Abdel-Mageed, AB; Agrawal, KC; Bhasin, N; Datta, A; Kim, H; Mondal, D; Ranjan, M; Rider, B | 1 |
| Huang, YP; Hung, CC; Ueng, TH; Wang, HW | 1 |
| Kim, YS; Milner, JA; Milner, MJ; Wang, TT | 1 |
| Lin, CH; Lin, PH | 1 |
| Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH | 1 |
| Fischer, B; Katschinski, DM; Navarrete Santos, A; Seifert, A; Tonack, S | 1 |
| Mason, ME; Okey, AB | 1 |
| Krishnan, V; Narasimhan, TR; Porter, W; Safe, S; Wang, X | 1 |
| Krishnan, V; Merchant, M; Safe, S | 1 |
| Lu, YF; Safe, S; Sun, G; Wang, X | 1 |
| Barton, SL; Burchiel, SW; Ethier, SP; Tannheimer, SL | 1 |
| Hoivik, D; Pollenz, R; Safe, S; Wang, F | 1 |
| Bartels, MJ; Carney, EW; Charles, GD; Freshour, NL; Gollapudi, BB; Zacharewski, TR | 1 |
| Bradshaw, TD; Brantley, E; Chua, MS; Kashiyama, E; Sausville, EA; Stevens, MF; Stinson, SF | 1 |
| Chirnomas, RB; Jeffy, BD; Romagnolo, DF | 1 |
19 other study(ies) available for alpha-naphthoflavone and Breast Cancer
| Article | Year |
|---|---|
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2022 |
4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors.
Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Triazoles | 2022 |
The Synthesis of Chalcones as Anticancer Prodrugs and their Bioactivation in CYP1 Expressing Breast Cancer Cells.
Topics: Antineoplastic Agents; Benzoflavones; Breast Neoplasms; Cell Line, Tumor; Chalcone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Flavones; Humans; Molecular Structure; Prodrugs | 2018 |
Selective targeting of FAK-Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoflavones; Breast Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Humans; MCF-7 Cells; Mice; Mice, Nude; Molecular Targeted Therapy; Protein Kinase Inhibitors; Xenograft Model Antitumor Assays | 2015 |
Antiestrogenic effects of motorcycle exhaust particulate in MCF-7 human breast cancer cells and immature female rats.
Topics: Air Pollutants; Animals; Benzo(a)pyrene; Benzoflavones; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Humans; Injections, Intraperitoneal; Motorcycles; Organ Size; Particle Size; Rats; Rats, Wistar; Receptors, Estrogen; Uterus; Vehicle Emissions | 2004 |
Estrogen receptor alpha as a target for indole-3-carbinol.
Topics: Anticarcinogenic Agents; Benzoflavones; Breast Neoplasms; Cell Count; Cell Line, Tumor; Dimerization; DNA, Complementary; Estrogen Receptor alpha; Gene Expression; Humans; Indoles; Luteolin; Oligonucleotide Array Sequence Analysis; Receptors, Aryl Hydrocarbon; RNA, Messenger; Vegetables | 2006 |
Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.
Topics: Benzoflavones; Breast Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Fluoresceins; Humans; Metyrapone; Molecular Structure; NAD; NADP; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Reactive Oxygen Species; Tamoxifen | 2006 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen | 2007 |
Significance of prolyl hydroxylase 2 in the interference of aryl hydrocarbon receptor and hypoxia-inducible factor-1 alpha signaling.
Topics: Benzoflavones; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Liver Neoplasms; Polychlorinated Dibenzodioxins; Procollagen-Proline Dioxygenase; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction | 2008 |
Aryl hydrocarbon hydroxylase activity in mouse, rat, and human mammary tumors.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Breast Neoplasms; Enzyme Induction; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microsomes; Rats | 1981 |
Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated decrease of the nuclear estrogen receptor in MCF-7 human breast cancer cells.
Topics: Analysis of Variance; Animals; Base Sequence; Benzoflavones; Blotting, Northern; Breast Neoplasms; Cell Nucleus; Cycloheximide; DNA; Humans; Molecular Sequence Data; Polychlorinated Dibenzodioxins; Protein Binding; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Signal Transduction; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Mechanism of action of alpha-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells.
Topics: Benzoflavones; Benzofurans; Breast Neoplasms; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Oxidoreductases; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Receptors, Estrogen; Tumor Cells, Cultured | 1993 |
Inhibition of prolactin receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 human breast cancer cells.
Topics: Benzoflavones; Breast Neoplasms; Environmental Pollutants; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Receptors, Prolactin; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1996 |
Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Benzoflavones; Breast; Breast Neoplasms; Calcium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Homeostasis; Humans; Intracellular Fluid; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons | 1997 |
Functional and physical interactions between the estrogen receptor Sp1 and nuclear aryl hydrocarbon receptor complexes.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Binding, Competitive; Breast Neoplasms; Cathepsin D; Cell Extracts; DNA; DNA-Binding Proteins; DNA, Antisense; Enhancer Elements, Genetic; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Protein Binding; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Recombinant Fusion Proteins; Sp1 Transcription Factor; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1998 |
Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay.
Topics: Benzo(a)pyrene; Benzoflavones; beta-Galactosidase; Breast Neoplasms; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression; Genes, Reporter; Genetic Techniques; Humans; Hydroxylation; Luciferases; Receptors, Estrogen; Transfection; Tumor Cells, Cultured | 2000 |
Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells.
Topics: Aniline Compounds; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzothiazoles; Breast Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; Isoenzymes; Mixed Function Oxygenases; Protein Binding; Substrate Specificity; Thiazoles; Tumor Cells, Cultured | 2000 |
Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzoflavones; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Carcinogens; DNA Damage; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |