alpha-n-carboxy-beta-n-methylaminoalanine has been researched along with Amyotrophic Lateral Sclerosis in 6 studies
*Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradley, WG; Cox, PA | 1 |
| Banack, SA; Murch, SJ | 1 |
| Vyas, KJ; Weiss, JH | 1 |
| Banack, SA; Bradley, WG; Codd, GA; Cox, PA; Metcalf, JS; Richer, R | 1 |
| Bradley, WG | 1 |
1 review(s) available for alpha-n-carboxy-beta-n-methylaminoalanine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Possible therapy for ALS based on the cyanobacteria/BMAA hypothesis.
Topics: Amino Acids; Amino Acids, Diamino; Amino Acids, Dicarboxylic; Amino Acyl-tRNA Synthetases; Amyotrophic Lateral Sclerosis; Cyanobacteria; Enzyme Inhibitors; Hair; Humans; Neurotoxins; Protein Transport | 2009 |
5 other study(ies) available for alpha-n-carboxy-beta-n-methylaminoalanine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Beyond Guam: cyanobacteria, BMAA and sporadic amyotrophic lateral sclerosis.
Topics: Amino Acids, Diamino; Amino Acids, Dicarboxylic; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Cyanobacteria; Cyanobacteria Toxins; Guam; Humans; Marine Toxins; Microcystins | 2009 |
Multiple neurotoxic items in the Chamorro diet link BMAA with ALS/PDC.
Topics: Amino Acids, Diamino; Amino Acids, Dicarboxylic; Amyotrophic Lateral Sclerosis; Cycas; Dementia; Diet; Foodborne Diseases; Gene Expression Regulation; Guam; Humans; Marine Toxins; Nerve Tissue Proteins; Protein Serine-Threonine Kinases; Seeds; TRPM Cation Channels | 2009 |
BMAA--an unusual cyanobacterial neurotoxin.
Topics: Amino Acids, Diamino; Amino Acids, Dicarboxylic; Amyotrophic Lateral Sclerosis; Animals; Bicarbonates; Cyanobacteria; Humans; Motor Neurons; Neurotoxins; Parkinson Disease; Receptors, Glutamate; Signal Transduction | 2009 |
Cyanobacteria and BMAA exposure from desert dust: a possible link to sporadic ALS among Gulf War veterans.
Topics: Amino Acids, Diamino; Amino Acids, Dicarboxylic; Aminobutyrates; Amyotrophic Lateral Sclerosis; Chromatography, High Pressure Liquid; Cyanobacteria; Disease Outbreaks; Ecosystem; Environmental Exposure; Gulf War; Humans; Retrospective Studies; Seasons; Tandem Mass Spectrometry; Veterans | 2009 |
Proceedings from the symposium "Beyond Guam: New aspects of the Cyanobacteria/BMAA Hypothesis", 4 November 2008, UK.
Topics: Amino Acids, Diamino; Amino Acids, Dicarboxylic; Amyotrophic Lateral Sclerosis; Bacterial Toxins; Cyanobacteria; Cyanobacteria Toxins; Guam; Humans; Marine Toxins; Microcystins | 2009 |