alpha-methylserotonin has been researched along with Muscle Contraction in 27 studies
alpha-methylserotonin: potent agonist at M & D receptors of serotonin; RN given refers to parent cpd
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 3 The additional smooth muscle contraction stimulated by 5-HT was increased in the presence of the competitive substrate inhibitor for nitric oxide synthase, NG-nitro-L-arginine methyl ester (L-NAME, 100 microM)." | 3.68 | Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery. ( Clark, AH; Garland, CJ; Seager, JM, 1992) |
| "1 Tegaserod (Zelnorm) is a potent 5-hydroxytryptamine4 (5-HT4) receptor agonist with clinical efficacy in disorders associated with reduced gastrointestinal motility and transit." | 1.32 | The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. ( Armstrong, SR; Beattie, DT; Humphrey, PP; Mai, N; Marquess, D; McCullough, JL; Pulido-Rios, T; Richardson, C; Sandlund, C; Smith, JA; Vickery, RG, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 19 (70.37) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wainscott, DB | 2 |
| Cohen, ML | 5 |
| Schenck, KW | 2 |
| Audia, JE | 1 |
| Nissen, JS | 1 |
| Baez, M | 2 |
| Kursar, JD | 2 |
| Lucaites, VL | 1 |
| Nelson, DL | 2 |
| Beattie, DT | 1 |
| Smith, JA | 1 |
| Marquess, D | 1 |
| Vickery, RG | 1 |
| Armstrong, SR | 1 |
| Pulido-Rios, T | 1 |
| McCullough, JL | 1 |
| Sandlund, C | 1 |
| Richardson, C | 1 |
| Mai, N | 1 |
| Humphrey, PP | 3 |
| Dunlop, J | 1 |
| Watts, SW | 1 |
| Barrett, JE | 1 |
| Coupet, J | 1 |
| Harrison, B | 1 |
| Mazandarani, H | 1 |
| Nawoschik, S | 1 |
| Pangalos, MN | 1 |
| Ramamoorthy, S | 1 |
| Schechter, L | 1 |
| Smith, D | 1 |
| Stack, G | 1 |
| Zhang, J | 1 |
| Zhang, G | 1 |
| Rosenzweig-Lipson, S | 1 |
| Spring, C | 1 |
| Mevissen, M | 2 |
| Reist, M | 1 |
| Zulauf, M | 1 |
| Steiner, A | 2 |
| Kaze, C | 1 |
| Hirsbrunner, G | 1 |
| Moffatt, JD | 1 |
| Cocks, TM | 1 |
| Page, CP | 1 |
| Trevethick, MA | 2 |
| Feniuk, W | 3 |
| Buchheit, KH | 1 |
| Buhl, T | 1 |
| Cushing, DJ | 2 |
| Schenck, K | 1 |
| Johnson, MP | 1 |
| Susemichel, A | 1 |
| Robertson, DW | 1 |
| Carter, D | 1 |
| Champney, M | 1 |
| Hwang, B | 1 |
| Eglen, RM | 1 |
| Fujiwara, T | 1 |
| Chiba, S | 1 |
| Ishizawa, M | 1 |
| Briejer, MR | 1 |
| Mathis, C | 1 |
| Schuurkes, JA | 1 |
| Dobbins, DE | 1 |
| Karlsson, C | 1 |
| Bodelsson, G | 1 |
| Bodelsson, M | 1 |
| Stjernquist, M | 1 |
| O'Gara, BA | 1 |
| Illuzzi, FA | 1 |
| Chung, M | 1 |
| Portnoy, AD | 1 |
| Fraga, K | 1 |
| Frieman, VB | 1 |
| Javid, FA | 1 |
| Naylor, RJ | 1 |
| Gong, H | 1 |
| Nakamura, T | 1 |
| Hattori, K | 1 |
| Ohnuki, T | 1 |
| Rashid, M | 1 |
| Nakazawa, M | 1 |
| Watanabe, K | 1 |
| Nagatomo, T | 1 |
| Tadipatri, S | 1 |
| Saxena, PR | 1 |
| Seager, JM | 1 |
| Clark, AH | 1 |
| Garland, CJ | 1 |
| Foy, RA | 1 |
| Myles, JL | 1 |
| Wilkerson, RD | 1 |
| Lai, FM | 1 |
| Tanikella, T | 1 |
| Cervoni, P | 1 |
| Fox, A | 1 |
| Morton, IK | 1 |
27 other studies available for alpha-methylserotonin and Muscle Contraction
| Article | Year |
|---|---|
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; | 1993 |
The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo.
Topics: Animals; Cell Membrane; Cells, Cultured; Colon; Cyclic AMP; Esophagus; Gastric Fundus; Gastrointesti | 2004 |
Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist.
Topics: Animals; Antipsychotic Agents; Binding Sites; Cell Line; CHO Cells; Cricetinae; Cricetulus; Heterocy | 2011 |
Modification of spontaneous contractility of smooth muscle preparations from the bovine abomasal antrum by serotonin receptor agonists.
Topics: Abomasum; Animals; Area Under Curve; Atropine; Cattle; Dose-Response Relationship, Drug; Female; Hex | 2003 |
Effect of endotoxins on contractility of smooth muscle preparations from the bovine abomasal antrum.
Topics: Abomasum; Animals; Area Under Curve; Carbachol; Cattle; Cholinergic Agonists; Dose-Response Relation | 2004 |
Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Boron Compounds; Botulinum | 2004 |
5-hydroxytryptamine-induced relaxation of neonatal porcine vena cava in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Cyclic AMP; Dinoprost; Histamine; Kinetics; | 1984 |
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding | 1994 |
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.
Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coron | 1994 |
DOI and alpha-methylserotonin: comparative vascular and nonvascular smooth muscle effects and central 5-hydroxytryptamine2 receptor affinities.
Topics: Amphetamines; Animals; Brain; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Re | 1993 |
Serotonin-induced contraction in porcine coronary artery: use of ergolines to support vascular 5-hydroxytryptamine2-receptor heterogeneity.
Topics: 5-Methoxytryptamine; Animals; Coronary Vessels; Endothelium, Vascular; Ergolines; In Vitro Technique | 1993 |
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter | 1995 |
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models, | 1995 |
Inhibitory action of 5-hydroxytryptamine on propulsive activity of the guinea-pig isolated colon.
Topics: 5-Methoxytryptamine; Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniq | 1996 |
5-HT receptor types in the rat ileum longitudinal muscle: focus on 5-HT2 receptors mediating contraction.
Topics: 5-Methoxytryptamine; Animals; Female; Gastrointestinal Motility; Ileum; In Vitro Techniques; Ketanse | 1997 |
Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb.
Topics: Animals; Dogs; Female; Lymphatic System; Male; Muscle Contraction; Muscle, Smooth; Phentolamine; Pre | 1998 |
Characterization of 5-hydroxytryptamine receptors mediating circular smooth muscle contraction in the human umbilical artery.
Topics: Adolescent; Adult; Female; Humans; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth; Pre | 1999 |
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Re | 1999 |
Characterisation of 5-HT2 receptor subtypes in the Suncus murinus intestine.
Topics: Amphetamines; Animals; Female; In Vitro Techniques; Indoles; Intestines; Male; Muscle Contraction; P | 1999 |
A novel 5-HT(2) antagonist, sarpogrelate hydrochloride, shows inhibitory effects on both contraction and relaxation mediated by 5-HT receptor subtypes in porcine coronary arteries.
Topics: Animals; Coronary Vessels; Ergonovine; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle R | 2000 |
Rabbit isolated renal artery contractions by some tryptamine derivatives, including 2-methyl-5-HT, are mediated by a 5-HT1-like receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; In Vitro Techniques; In | 1992 |
Endothelium-dependent contractile responses to 5-hydroxytryptamine in the rabbit basilar artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Basilar Artery; Endothelium, Vascular; Fe | 1992 |
Characterization of 5-hydroxytryptamine receptors in bovine coronary arteries.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cattle; Dose-Response Relationship, Drug; Endotheli | 1992 |
Characterization of serotonin receptors in isolated rat intramyocardial coronary artery.
Topics: Animals; Coronary Vessels; Dinoprost; Endothelium; Ketanserin; Kinetics; Male; Muscle Contraction; M | 1991 |
Canine, but not rat bladder contracts to serotonin via activation of 5HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dogs; Dose-Response Relationship, Drug; Ergolines; | 1990 |
An examination of the 5-HT3 receptor mediating contraction and evoked [3H]-acetylcholine release in the guinea-pig ileum.
Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Male; Muscle Contractio | 1990 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; D | 1986 |