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alpha-methylphenylalanine and BH4 Deficiency

alpha-methylphenylalanine has been researched along with BH4 Deficiency in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (56.25)	18.7374
1990's	5 (31.25)	18.2507
2000's	2 (12.50)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Del Valle, JA; Greengard, O; Yoss, MS	1
Costabeber, E; de Souza Wyse, AT; Kessler, A; Severo Dutra-Filho, C; Wajner, M; Wannmacher, CM	1
Benevenga, NJ; Steele, RD	1
Lane, JD; Langenbeck, U; Neuhoff, V; Schöne, B	1
Lane, JD; Neuhoff, V	1
Berry, HK; Butcher, RE; Vorhees, CV	1
Blumstein, L; Levitsky, DA; Strupp, BJ	1
Brass, CA; Greengard, O	1
Huether, G; Neuhoff, V	1
Brass, CA; Greengard, O; Isaacs, CE; McChesney, R	1
Burri, R; Herschkowitz, N; Reynolds, R	1
Ciaramitaro, V; Diamond, A; Djali, S; Donner, E; Robinson, MB	1
Cunha-Filho, JS; Milton, C; Sarkis, JJ; Schetinger, MR; Teixeira, MV; Wajner, M; Wannmacher, D; Wyse, AT	1
Austic, RE; Levitsky, DA; Strupp, BJ; Su, CL	1
Borges, LF; Floriano, PJ; Noriler, ME; Silva, CG; Wajner, M; Wannmacher, CM; Wyse, AT	1
Bridi, R; Dutra-Filho, CS; Kienzle Hagen, ME; Pederzolli, CD; Sgaravatti, AM; Wajner, M; Wannmacher, CM; Wyse, AT	1

Reviews

2 review(s) available for alpha-methylphenylalanine and BH4 Deficiency

Article	Year
Adverse effects of excessive consumption of amino acids. Annual review of nutrition, 1984, Volume: 4 Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Animal; Ethionine; Fenclonine; Glycine; Growth Disorders; Histidine; Humans; Methionine; Nerve Tissue Proteins; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pneumonia, Atypical Interstitial, of Cattle; Serine; Stereoisomerism; Sulfhydryl Compounds; Tissue Distribution; Tryptophan; Tyrosine; Vitamin A	1984
Progress in experimental phenylketonuria: a critical review. Neuroscience and biobehavioral reviews, 1981,Spring, Volume: 5, Issue:1 Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glutamates; Humans; Mice; Myelin Sheath; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Protein Biosynthesis; Pyridoxine; Serotonin	1981

Article

Year

Adverse effects of excessive consumption of amino acids.

Annual review of nutrition, 1984, Volume: 4

Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Animal; Ethionine; Fenclonine; Glycine; Growth Disorders; Histidine; Humans; Methionine; Nerve Tissue Proteins; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pneumonia, Atypical Interstitial, of Cattle; Serine; Stereoisomerism; Sulfhydryl Compounds; Tissue Distribution; Tryptophan; Tyrosine; Vitamin A

1984

Progress in experimental phenylketonuria: a critical review.

Neuroscience and biobehavioral reviews, 1981,Spring, Volume: 5, Issue:1

Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glutamates; Humans; Mice; Myelin Sheath; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Protein Biosynthesis; Pyridoxine; Serotonin

1981

Other Studies

14 other study(ies) available for alpha-methylphenylalanine and BH4 Deficiency

Article	Year
Alpha-methylphenylalanine, a new inducer of chronic hyperphenylalaninemia in sucling rats. Science (New York, N.Y.), 1976, Jun-04, Volume: 192, Issue:4243 Topics: Amino Acids; Animals; Animals, Newborn; Disease Models, Animal; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats	1976
Hyperphenylalaninemia reduces creatine kinase activity in the cerebral cortex of rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:2 Topics: Animals; Cerebral Cortex; Creatine Kinase; Enzyme Inhibitors; In Vitro Techniques; Phenylalanine; Phenylketonurias; Rats; Rats, Wistar	2003
Characterization of experimental phenylketonuria. Augmentation of hyperphenylalaninemia with alpha-methylphenylalanine and p-chlorophenylalanine. Biochimica et biophysica acta, 1980, Jan-17, Volume: 627, Issue:2 Topics: Age Factors; Amino Acids; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Disease Models, Animal; Fenclonine; Humans; Learning; Myelin Proteins; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Rats	1980
Phenylketonuria: clinical and experimental considerations revealed by the use of animal models. Die Naturwissenschaften, 1980, Volume: 67, Issue:5 Topics: Animals; Brain; Cerebellum; Disease Models, Animal; Fenclonine; Humans; Male; Neurons; Phenylalanine; Phenylketonurias; Rats	1980
PKU, learning, and models of mental retardation. Developmental psychobiology, 1984, Volume: 17, Issue:2 Topics: Animals; Body Weight; Disease Models, Animal; Humans; Intellectual Disability; Learning; Phenylalanine; Phenylketonurias; Psychological Tests; Rats	1984
Developmental changes of cerebral phenylalanine uptake from severely elevated blood levels. Neurochemical research, 1984, Volume: 9, Issue:6 Topics: Age Factors; Animals; Brain; Brain Chemistry; Humans; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred F344	1984
Use of alpha-methylphenylalanine for studies of brain development in experimental phenylketonuria. Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2 Topics: Animals; Brain; Cell Division; Cell Survival; Cerebellum; Disease Models, Animal; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats	1981
The effects of hyperphenylalaninemia on fetal development: a new animal model of maternal phenylketonuria. Pediatric research, 1982, Volume: 16, Issue:5 Topics: Animals; Brain; Diet; Female; Fetus; Growth; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred F344	1982
Retarded development of neurons and oligodendroglia in rat forebrain produced by hyperphenylalaninemia results in permanent deficits in myelin despite long recovery periods. Experimental neurology, 1993, Volume: 124, Issue:2 Topics: Animals; Animals, Newborn; Axons; Corpus Callosum; Disease Models, Animal; Female; Male; Molecular Weight; Myelin Basic Protein; Myelin Sheath; Neurofilament Proteins; Neurons; Oligodendroglia; Phenylalanine; Phenylketonurias; Prosencephalon; Rats; Rats, Sprague-Dawley	1993
An animal model of early-treated PKU. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:5 Pt 2 Topics: Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Drug Therapy, Combination; Fetus; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred Strains; Time Factors	1994
Effect of phenylalanine and its metabolites on ATP diphosphohydrolase activity in synaptosomes from rat cerebral cortex. Neurochemical research, 1994, Volume: 19, Issue:9 Topics: Animals; Apyrase; Cerebral Cortex; Disease Models, Animal; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Rats, Wistar; Synaptosomes	1994
Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria. The American journal of clinical nutrition, 1999, Volume: 69, Issue:4 Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Brain; Brain Chemistry; Diet; Embryonic and Fetal Development; Female; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Long-Evans	1999
Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria. Metabolic brain disease, 1999, Volume: 14, Issue:2 Topics: Alanine; Animals; Animals, Newborn; Cerebral Cortex; Injections, Subcutaneous; Phenylalanine; Phenylketonurias; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	1999
Experimental hyperphenylalaninemia provokes oxidative stress in rat brain. Biochimica et biophysica acta, 2002, Apr-24, Volume: 1586, Issue:3 Topics: Animals; Animals, Newborn; Brain; Catalase; Glutathione Peroxidase; Luminescent Measurements; Oxidative Stress; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Rats, Wistar; Superoxide Dismutase	2002