alpha-hydroxyglutarate has been researched along with Polycystic Kidney Diseases in 1 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since polycystic kidney disease (PKD) was first noted over 30 years ago to have neoplastic parallels, there has been a resurgent interest in elucidating neoplasia-relevant pathways in PKD." | 1.42 | The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. ( Bell, PD; Guay-Woodford, LM; Hammock, B; Hwang, VJ; Kim, J; Rand, A; Sturdivant, S; Weiss, RH; Yang, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hwang, VJ | 1 |
| Kim, J | 1 |
| Rand, A | 1 |
| Yang, C | 1 |
| Sturdivant, S | 1 |
| Hammock, B | 1 |
| Bell, PD | 1 |
| Guay-Woodford, LM | 1 |
| Weiss, RH | 1 |
1 other study available for alpha-hydroxyglutarate and Polycystic Kidney Diseases
| Article | Year |
|---|---|
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.
Topics: Animals; Cells, Cultured; Creatine Kinase; Disease Models, Animal; DNA Mutational Analysis; Enzyme I | 2015 |