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alpha-hydroxyglutarate and Polycystic Kidney Diseases

alpha-hydroxyglutarate has been researched along with Polycystic Kidney Diseases in 1 studies

2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.

Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.

Research Excerpts

ExcerptRelevanceReference
"Since polycystic kidney disease (PKD) was first noted over 30 years ago to have neoplastic parallels, there has been a resurgent interest in elucidating neoplasia-relevant pathways in PKD."1.42The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. ( Bell, PD; Guay-Woodford, LM; Hammock, B; Hwang, VJ; Kim, J; Rand, A; Sturdivant, S; Weiss, RH; Yang, C, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hwang, VJ1
Kim, J1
Rand, A1
Yang, C1
Sturdivant, S1
Hammock, B1
Bell, PD1
Guay-Woodford, LM1
Weiss, RH1

Other Studies

1 other study available for alpha-hydroxyglutarate and Polycystic Kidney Diseases

ArticleYear
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.
    American journal of physiology. Renal physiology, 2015, Sep-15, Volume: 309, Issue:6

    Topics: Animals; Cells, Cultured; Creatine Kinase; Disease Models, Animal; DNA Mutational Analysis; Enzyme I

2015