alpha-hydroxyglutarate has been researched along with Muscle Disorders in 2 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There were also increases in plasma 2HG in CER-treated rats on Days 8 and 11 and in TMPD-treated rats at 24 hr after dosing and increases in plasma hexanoylcarnitine in CER-treated rats on Day 11 and in TMPD-treated rats at 6 and 24 hr after dosing." | 1.46 | Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. ( Asai, F; Kobayashi, N; Nezu, Y; Obayashi, H; Shirai, M; Yamoto, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obayashi, H | 1 |
| Kobayashi, N | 1 |
| Nezu, Y | 1 |
| Yamoto, T | 1 |
| Shirai, M | 1 |
| Asai, F | 1 |
| Takayanagi, M | 1 |
| Ogawa, A | 1 |
1 review available for alpha-hydroxyglutarate and Muscle Disorders
| Article | Year |
|---|---|
[D-2-hydroxyglutaric aciduria].
Topics: Biomarkers; Cardiomyopathy, Dilated; Central Nervous System Diseases; Diagnosis, Differential; gamma | 1998 |
1 other study available for alpha-hydroxyglutarate and Muscle Disorders
| Article | Year |
|---|---|
Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats.
Topics: Aniline Compounds; Animals; Biomarkers; Carnitine; Creatine Kinase; Disease Models, Animal; Glutarat | 2017 |