alpha-hydroxyglutarate has been researched along with Decreased Muscle Tone in 5 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The phenotype appears to include mental retardation, macrocephaly, hypotonia, seizures, and involuntary movements, although neurologic and systemic manifestations of the disorder varied considerably between individual patients, even within the same family." | 1.29 | D-2-hydroxyglutaric aciduria. ( Bowe, C; Curry, CJ; Duran, M; Holmes, B; Jakobs, C; Nyhan, WL; Shelton, GD; Sweetman, L; Vance, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahfoud, A | 1 |
| Domínguez, CL | 1 |
| Rashed, M | 1 |
| Durán, M | 2 |
| Rodríguez, T | 1 |
| Rodríguez, D | 1 |
| Landa, V | 1 |
| Read, MH | 1 |
| Bonamy, C | 1 |
| Laloum, D | 1 |
| Belloy, F | 1 |
| Constans, JM | 1 |
| Guillois, B | 1 |
| Kottler, ML | 1 |
| Verhoeven, NM | 1 |
| Jakobs, C | 3 |
| Nyhan, WL | 2 |
| Shelton, GD | 1 |
| Holmes, B | 1 |
| Bowe, C | 1 |
| Curry, CJ | 1 |
| Vance, C | 1 |
| Sweetman, L | 1 |
| Baker, NS | 1 |
| Sarnat, HB | 1 |
| Jack, RM | 1 |
| Patterson, K | 1 |
| Shaw, DW | 1 |
| Herndon, SP | 1 |
| van der Knaap, MS | 1 |
| Hoffmann, GF | 1 |
| Renier, WO | 1 |
| Smeitink, JA | 1 |
| Catsman-Berrevoets, CE | 1 |
| Hjalmarson, O | 1 |
| Vallance, H | 1 |
| Sugita, K | 1 |
| Bowe, CM | 1 |
| Herrin, JT | 1 |
| Craigen, WJ | 1 |
| Buist, NR | 1 |
| Brookfield, DS | 1 |
| Chalmers, RA | 1 |
5 other studies available for alpha-hydroxyglutarate and Decreased Muscle Tone
| Article | Year |
|---|---|
[D-2-hydroxyglutaric aciduria. Report of two cases].
Topics: Anticonvulsants; Atrophy; Brain; Brain Diseases, Metabolic, Inborn; Carnitine; Child, Preschool; Con | 2009 |
Clinical, biochemical, magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) findings in a fourth case of combined D- and L-2 hydroxyglutaric aciduria.
Topics: Brain; Brain Diseases, Metabolic, Inborn; Cysts; Electroencephalography; Fatal Outcome; Female; Fuma | 2005 |
D-2-hydroxyglutaric aciduria.
Topics: Animals; Biopsy; Brain Diseases, Metabolic; Child; Child, Preschool; Dog Diseases; Dogs; Female; Gas | 1995 |
D-2-hydroxyglutaric aciduria: hypotonia, cortical blindness, seizures, cardiomyopathy, and cylindrical spirals in skeletal muscle.
Topics: Amino Acid Metabolism, Inborn Errors; Blindness; Brain Diseases; Cardiomyopathies; Electroencephalog | 1997 |
D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity?
Topics: Biomarkers; Cerebral Ventricles; Child, Preschool; Chorea; Cysts; Ependyma; Epilepsy; Family Health; | 1999 |