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alpha-hydroxyglutarate and Decreased Muscle Tone

alpha-hydroxyglutarate has been researched along with Decreased Muscle Tone in 5 studies

2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"The phenotype appears to include mental retardation, macrocephaly, hypotonia, seizures, and involuntary movements, although neurologic and systemic manifestations of the disorder varied considerably between individual patients, even within the same family."1.29D-2-hydroxyglutaric aciduria. ( Bowe, C; Curry, CJ; Duran, M; Holmes, B; Jakobs, C; Nyhan, WL; Shelton, GD; Sweetman, L; Vance, C, 1995)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mahfoud, A1
Domínguez, CL1
Rashed, M1
Durán, M2
Rodríguez, T1
Rodríguez, D1
Landa, V1
Read, MH1
Bonamy, C1
Laloum, D1
Belloy, F1
Constans, JM1
Guillois, B1
Kottler, ML1
Verhoeven, NM1
Jakobs, C3
Nyhan, WL2
Shelton, GD1
Holmes, B1
Bowe, C1
Curry, CJ1
Vance, C1
Sweetman, L1
Baker, NS1
Sarnat, HB1
Jack, RM1
Patterson, K1
Shaw, DW1
Herndon, SP1
van der Knaap, MS1
Hoffmann, GF1
Renier, WO1
Smeitink, JA1
Catsman-Berrevoets, CE1
Hjalmarson, O1
Vallance, H1
Sugita, K1
Bowe, CM1
Herrin, JT1
Craigen, WJ1
Buist, NR1
Brookfield, DS1
Chalmers, RA1

Other Studies

5 other studies available for alpha-hydroxyglutarate and Decreased Muscle Tone

ArticleYear
[D-2-hydroxyglutaric aciduria. Report of two cases].
    Investigacion clinica, 2009, Volume: 50, Issue:3

    Topics: Anticonvulsants; Atrophy; Brain; Brain Diseases, Metabolic, Inborn; Carnitine; Child, Preschool; Con

2009
Clinical, biochemical, magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) findings in a fourth case of combined D- and L-2 hydroxyglutaric aciduria.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

    Topics: Brain; Brain Diseases, Metabolic, Inborn; Cysts; Electroencephalography; Fatal Outcome; Female; Fuma

2005
D-2-hydroxyglutaric aciduria.
    Journal of child neurology, 1995, Volume: 10, Issue:2

    Topics: Animals; Biopsy; Brain Diseases, Metabolic; Child; Child, Preschool; Dog Diseases; Dogs; Female; Gas

1995
D-2-hydroxyglutaric aciduria: hypotonia, cortical blindness, seizures, cardiomyopathy, and cylindrical spirals in skeletal muscle.
    Journal of child neurology, 1997, Volume: 12, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Blindness; Brain Diseases; Cardiomyopathies; Electroencephalog

1997
D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity?
    Annals of neurology, 1999, Volume: 45, Issue:1

    Topics: Biomarkers; Cerebral Ventricles; Child, Preschool; Chorea; Cysts; Ependyma; Epilepsy; Family Health;

1999