alpha-hydroxyglutarate has been researched along with Cardiomyopathies, Primary in 5 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
Excerpt | Relevance | Reference |
---|---|---|
"Hematologic malignancies are frequently associated with cardiac pathologies." | 1.43 | Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart. ( Goodell, MA; Harmancey, R; Karlstaedt, A; Taegtmeyer, H; Vasquez, H; Vitrac, H; Wang, JH; Zhang, X, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
Authors | Studies |
---|---|
Ribeiro, RT | 1 |
Roginski, AC | 1 |
Marschner, RA | 1 |
Wajner, SM | 1 |
Castilho, RF | 1 |
Amaral, AU | 1 |
Wajner, M | 1 |
Akbay, EA | 1 |
Moslehi, J | 1 |
Christensen, CL | 1 |
Saha, S | 1 |
Tchaicha, JH | 1 |
Ramkissoon, SH | 1 |
Stewart, KM | 1 |
Carretero, J | 1 |
Kikuchi, E | 1 |
Zhang, H | 1 |
Cohoon, TJ | 1 |
Murray, S | 1 |
Liu, W | 1 |
Uno, K | 1 |
Fisch, S | 1 |
Jones, K | 1 |
Gurumurthy, S | 1 |
Gliser, C | 1 |
Choe, S | 1 |
Keenan, M | 1 |
Son, J | 1 |
Stanley, I | 1 |
Losman, JA | 1 |
Padera, R | 1 |
Bronson, RT | 1 |
Asara, JM | 1 |
Abdel-Wahab, O | 1 |
Amrein, PC | 1 |
Fathi, AT | 1 |
Danial, NN | 1 |
Kimmelman, AC | 1 |
Kung, AL | 1 |
Ligon, KL | 1 |
Yen, KE | 1 |
Kaelin, WG | 1 |
Bardeesy, N | 1 |
Wong, KK | 1 |
Karlstaedt, A | 1 |
Zhang, X | 1 |
Vitrac, H | 1 |
Harmancey, R | 1 |
Vasquez, H | 1 |
Wang, JH | 1 |
Goodell, MA | 1 |
Taegtmeyer, H | 1 |
Baker, NS | 1 |
Sarnat, HB | 1 |
Jack, RM | 1 |
Patterson, K | 1 |
Shaw, DW | 1 |
Herndon, SP | 1 |
Wajne, M | 1 |
Vargas, CR | 1 |
Funayama, C | 1 |
Fernandez, A | 1 |
Elias, ML | 1 |
Goodman, SI | 1 |
Jakobs, C | 1 |
van der Knaap, MS | 1 |
5 other studies available for alpha-hydroxyglutarate and Cardiomyopathies, Primary
Article | Year |
---|---|
Disruption of mitochondrial bioenergetics, calcium retention capacity and cell viability caused by D-2-hydroxyglutaric acid in the heart.
Topics: Animals; Calcium; Cardiomyopathies; Cell Survival; Creatine Kinase; Energy Metabolism; Rats | 2023 |
D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.
Topics: Animals; Cardiomyopathies; Cell Line; Gene Expression Profiling; Gene Expression Regulation, Develop | 2014 |
Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.
Topics: Acetylation; Animals; ATP Citrate (pro-S)-Lyase; Cardiomyopathies; Glutarates; Hematologic Neoplasms | 2016 |
D-2-hydroxyglutaric aciduria: hypotonia, cortical blindness, seizures, cardiomyopathy, and cylindrical spirals in skeletal muscle.
Topics: Amino Acid Metabolism, Inborn Errors; Blindness; Brain Diseases; Cardiomyopathies; Electroencephalog | 1997 |
D-2-Hydroxyglutaric aciduria in a patient with a severe clinical phenotype and unusual MRI findings.
Topics: Brain; Cardiomyopathies; Cells, Cultured; Citrate (si)-Synthase; Electron Transport Complex IV; Fibr | 2002 |