alpha-hydroxyglutarate has been researched along with Breast Neoplasms in 6 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metabolic reprogramming in breast tumors is linked to increases in putative oncogenic metabolites that may contribute to malignant transformation." | 1.48 | ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming. ( Amable, L; Ambs, S; Bustin, M; Deng, T; Dorsey, TH; Jin, F; Killian, JK; Lee, DH; Liu, W; Minas, TZ; Mishra, P; Putluri, N; Putluri, V; Sreekumar, A; Tang, W; Wang, F; Wang, Y; Yfantis, HG; Zhang, S; Zhu, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mishra, P | 2 |
| Tang, W | 1 |
| Putluri, V | 2 |
| Dorsey, TH | 2 |
| Jin, F | 1 |
| Wang, F | 1 |
| Zhu, D | 1 |
| Amable, L | 1 |
| Deng, T | 1 |
| Zhang, S | 1 |
| Killian, JK | 2 |
| Wang, Y | 1 |
| Minas, TZ | 1 |
| Yfantis, HG | 2 |
| Lee, DH | 2 |
| Sreekumar, A | 2 |
| Bustin, M | 1 |
| Liu, W | 1 |
| Putluri, N | 2 |
| Ambs, S | 2 |
| Seok, J | 1 |
| Yoon, SH | 1 |
| Lee, SH | 1 |
| Jung, JH | 1 |
| Lee, YM | 1 |
| Terunuma, A | 1 |
| Mathé, EA | 1 |
| Yi, M | 1 |
| Wallace, TA | 1 |
| Issaq, HJ | 1 |
| Zhou, M | 1 |
| Stevenson, HS | 1 |
| Karoly, ED | 1 |
| Chan, K | 1 |
| Samanta, S | 1 |
| Prieto, D | 1 |
| Hsu, TY | 1 |
| Kurley, SJ | 1 |
| Sonavane, R | 1 |
| Edelman, DC | 1 |
| Wulff, J | 1 |
| Starks, AM | 1 |
| Yang, Y | 1 |
| Kittles, RA | 1 |
| Ioffe, OB | 1 |
| Schiff, R | 1 |
| Stephens, RM | 1 |
| Meltzer, PS | 1 |
| Veenstra, TD | 1 |
| Westbrook, TF | 1 |
| Fathi, AT | 1 |
| Sadrzadeh, H | 1 |
| Comander, AH | 1 |
| Higgins, MJ | 1 |
| Bardia, A | 1 |
| Perry, A | 1 |
| Burke, M | 1 |
| Silver, R | 1 |
| Matulis, CR | 1 |
| Straley, KS | 1 |
| Yen, KE | 1 |
| Agresta, S | 1 |
| Kim, H | 1 |
| Schenkein, DP | 1 |
| Borger, DR | 1 |
| Smolková, K | 1 |
| Dvořák, A | 1 |
| Zelenka, J | 1 |
| Vítek, L | 1 |
| Ježek, P | 1 |
| Churchill, H | 1 |
| Naina, H | 1 |
| Boriack, R | 1 |
| Rakheja, D | 1 |
| Chen, W | 1 |
6 other studies available for alpha-hydroxyglutarate and Breast Neoplasms
| Article | Year |
|---|---|
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.
Topics: Alcohol Oxidoreductases; Breast Neoplasms; Cell Dedifferentiation; Cellular Reprogramming; Female; G | 2018 |
The oncometabolite d‑2‑hydroxyglutarate induces angiogenic activity through the vascular endothelial growth factor receptor 2 signaling pathway.
Topics: Angiogenesis Inhibitors; Breast Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Focal A | 2019 |
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Topics: Alcohol Oxidoreductases; Apoptosis; Breast Neoplasms; DNA Methylation; Female; Gene Expression Regul | 2014 |
Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.
Topics: Adenocarcinoma; Breast Neoplasms; Female; Glutarates; Humans; Isocitrate Dehydrogenase; Middle Aged; | 2014 |
Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Female; Glutarates; Humans; Iso | 2015 |
Discordant intracellular and plasma D-2-hydroxyglutarate levels in a patient with IDH2 mutated angioimmunoblastic T-cell lymphoma.
Topics: Aged, 80 and over; Breast Neoplasms; Chromatography, Liquid; Dioxygenases; DNA-Binding Proteins; Fem | 2015 |