alpha-hydroxyglutarate has been researched along with Aura in 11 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The older sister presented with severe mental retardation, recurrent epileptic seizures, and progressive deterioration in her ability to walk and to talk; she is now confined to a wheelchair with severe speech deficit." | 1.33 | L-2-Hydroxyglutaric aciduria: clinical, genetic, and brain MRI characteristics in two adult sisters. ( Duprez, TP; Goffette, SM; Jakobs, C; Nassogne, MC; Sindic, CJ; Vincent, MF, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Winkler, F | 1 |
| Saidha, S | 1 |
| Murphy, S | 1 |
| McCarthy, P | 1 |
| Mayne, PD | 1 |
| Hennessy, M | 1 |
| Andronesi, OC | 1 |
| Kim, GS | 1 |
| Gerstner, E | 1 |
| Batchelor, T | 1 |
| Tzika, AA | 1 |
| Fantin, VR | 1 |
| Vander Heiden, MG | 1 |
| Sorensen, AG | 1 |
| Clarke, NF | 1 |
| Andrews, I | 1 |
| Carpenter, K | 1 |
| Jakobs, C | 5 |
| van der Knaap, MS | 3 |
| Kirk, EP | 1 |
| Moroni, I | 1 |
| Bugiani, M | 1 |
| D'Incerti, L | 1 |
| Maccagnano, C | 1 |
| Rimoldi, M | 1 |
| Bissola, L | 1 |
| Pollo, B | 1 |
| Finocchiaro, G | 1 |
| Uziel, G | 1 |
| Seijo-Martínez, M | 1 |
| Navarro, C | 1 |
| Castro del Río, M | 1 |
| Vila, O | 1 |
| Puig, M | 1 |
| Ribes, A | 1 |
| Butron, M | 1 |
| Goffette, SM | 1 |
| Duprez, TP | 1 |
| Nassogne, MC | 1 |
| Vincent, MF | 1 |
| Sindic, CJ | 1 |
| Lee, C | 1 |
| Born, M | 1 |
| Salomons, GS | 1 |
| Woelfle, J | 1 |
| Geerts, Y | 1 |
| Renier, WO | 2 |
| Bakkeren, J | 1 |
| de Jong, J | 1 |
| Hoffmann, GF | 2 |
| Nyhan, WL | 1 |
| Smeitink, JA | 1 |
| Catsman-Berrevoets, CE | 1 |
| Hjalmarson, O | 1 |
| Vallance, H | 1 |
| Sugita, K | 1 |
| Bowe, CM | 1 |
| Herrin, JT | 1 |
| Craigen, WJ | 1 |
| Buist, NR | 1 |
| Brookfield, DS | 1 |
| Chalmers, RA | 1 |
| Muntau, AC | 1 |
| Röschinger, W | 1 |
| Merkenschlager, A | 1 |
| Duran, M | 1 |
| Roscher, AA | 1 |
2 reviews available for alpha-hydroxyglutarate and Aura
| Article | Year |
|---|---|
L-2-hydroxyglutaric aciduria and brain malignant tumors: a predisposing condition?
Topics: Adolescent; Adult; Astrocytoma; Brain Diseases, Metabolic; Brain Neoplasms; Cerebellar Ataxia; Child | 2004 |
2-Hydroxyglutaric aciduria: a case report on an infant with the D-isomeric form with review of the literature.
Topics: Epilepsy; Glutarates; Humans; Infant; Isomerism; Male; Psychomotor Disorders; Renal Aminoacidurias | 1996 |
9 other studies available for alpha-hydroxyglutarate and Aura
| Article | Year |
|---|---|
Understanding epilepsy in IDH-mutated gliomas: towards a targeted therapy.
Topics: Epilepsy; Glioma; Glutarates; Humans; Isocitrate Dehydrogenase; TOR Serine-Threonine Kinases | 2022 |
L-2-hydroxyglutaric aciduria diagnosed in an adult presenting with acute deterioration.
Topics: Adult; Ataxia; Brain; Disease Progression; Epilepsy; Glutarates; Humans; Lysine; Male; Metabolism, I | 2010 |
Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy.
Topics: Adult; Aged; Biopsy; Brain Neoplasms; Epilepsy; Female; Glioma; Glutarates; Humans; Isocitrate Dehyd | 2012 |
D-2-hydroxyglutaric aciduria: a case with an intermediate phenotype and prenatal diagnosis of two affected fetuses.
Topics: Adult; Amniotic Fluid; Craniofacial Abnormalities; Developmental Disabilities; Epilepsy; Female; Glu | 2003 |
L-2-hydroxyglutaric aciduria: clinical, neuroimaging, and neuropathological findings.
Topics: Adolescent; Atrophy; Brain; Brain Diseases, Metabolic, Inborn; Epilepsy; Fatal Outcome; Folic Acid; | 2005 |
L-2-Hydroxyglutaric aciduria: clinical, genetic, and brain MRI characteristics in two adult sisters.
Topics: Adult; Age of Onset; Brain; Electromyography; Epilepsy; Female; Glutarates; Humans; Intellectual Dis | 2006 |
Hemiconvulsion-hemiplegia-epilepsy syndrome as a presenting feature of L-2-hydroxyglutaric aciduria.
Topics: Epilepsy; Female; Glutarates; Hemiplegia; Humans; Infant; Metabolism, Inborn Errors; Syndrome | 2006 |
D-2-Hydroxyglutaric aciduria: biochemical marker or clinical disease entity?
Topics: Biomarkers; Cerebral Ventricles; Child, Preschool; Chorea; Cysts; Ependyma; Epilepsy; Family Health; | 1999 |
Combined D-2- and L-2-hydroxyglutaric aciduria with neonatal onset encephalopathy: a third biochemical variant of 2-hydroxyglutaric aciduria?
Topics: Biomarkers; Brain; Brain Diseases, Metabolic, Inborn; Chromatography, Gas; Diagnosis, Differential; | 2000 |