alpha-hydroxyglutarate has been researched along with Anaplastic Oligodendroglioma in 9 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous ex vivo spectroscopic data from tissue samples revealed differences in phospholipid metabolites between isocitrate dehydrogenase mutated (IDHmut) and IDH wildtype (IDHwt) gliomas." | 3.91 | In vivo Metabolic Profiles as Determined by ( Bähr, O; Franz, K; Hattingen, E; Pilatus, U; Steinbach, J; Wenger, KJ, 2019) |
| "Mixed oligoastrocytoma is losing popularity as a diagnostic term because most cases will fall into either the FA or OD category." | 2.52 | Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas. ( Macaulay, RJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| An, Z | 2 |
| Tiwari, V | 2 |
| Ganji, SK | 1 |
| Baxter, J | 2 |
| Levy, M | 2 |
| Pinho, MC | 1 |
| Pan, E | 2 |
| Maher, EA | 2 |
| Patel, TR | 2 |
| Mickey, BE | 2 |
| Choi, C | 2 |
| Wenger, KJ | 1 |
| Hattingen, E | 1 |
| Franz, K | 1 |
| Steinbach, J | 1 |
| Bähr, O | 1 |
| Pilatus, U | 1 |
| Hatanpaa, KJ | 1 |
| Navis, AC | 1 |
| Niclou, SP | 1 |
| Fack, F | 1 |
| Stieber, D | 1 |
| van Lith, S | 1 |
| Verrijp, K | 1 |
| Wright, A | 1 |
| Stauber, J | 1 |
| Tops, B | 1 |
| Otte-Holler, I | 1 |
| Wevers, RA | 1 |
| van Rooij, A | 1 |
| Pusch, S | 1 |
| von Deimling, A | 1 |
| Tigchelaar, W | 1 |
| van Noorden, CJ | 1 |
| Wesseling, P | 1 |
| Leenders, WP | 1 |
| Chittaranjan, S | 1 |
| Chan, S | 1 |
| Yang, C | 1 |
| Yang, KC | 1 |
| Chen, V | 1 |
| Moradian, A | 1 |
| Firme, M | 1 |
| Song, J | 1 |
| Go, NE | 1 |
| Blough, MD | 1 |
| Chan, JA | 1 |
| Cairncross, JG | 1 |
| Gorski, SM | 1 |
| Morin, GB | 1 |
| Yip, S | 1 |
| Marra, MA | 1 |
| Macaulay, RJ | 1 |
| Reitman, ZJ | 2 |
| Yan, H | 2 |
| Jin, G | 1 |
| Karoly, ED | 1 |
| Spasojevic, I | 1 |
| Yang, J | 1 |
| Kinzler, KW | 1 |
| He, Y | 1 |
| Bigner, DD | 1 |
| Vogelstein, B | 1 |
| Moroni, I | 1 |
| Bugiani, M | 1 |
| D'Incerti, L | 1 |
| Maccagnano, C | 1 |
| Rimoldi, M | 1 |
| Bissola, L | 1 |
| Pollo, B | 1 |
| Finocchiaro, G | 1 |
| Uziel, G | 1 |
3 reviews available for alpha-hydroxyglutarate and Anaplastic Oligodendroglioma
| Article | Year |
|---|---|
Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas.
Topics: Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; DNA Helicases; Genes, p53; Glioma; Glutarates; Huma | 2015 |
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
Topics: Animals; Arginine; Brain Neoplasms; Codon; Gene Expression Regulation, Enzymologic; Gene Expression | 2010 |
L-2-hydroxyglutaric aciduria and brain malignant tumors: a predisposing condition?
Topics: Adolescent; Adult; Astrocytoma; Brain Diseases, Metabolic; Brain Neoplasms; Cerebellar Ataxia; Child | 2004 |
6 other studies available for alpha-hydroxyglutarate and Anaplastic Oligodendroglioma
| Article | Year |
|---|---|
Echo-planar spectroscopic imaging with dual-readout alternated gradients (DRAG-EPSI) at 7 T: Application for 2-hydroxyglutarate imaging in glioma patients.
Topics: Adult; Biomarkers; Brain Neoplasms; Echo-Planar Imaging; Female; Glioma; Glutarates; Humans; Image P | 2018 |
In vivo Metabolic Profiles as Determined by
Topics: Adult; Aged; Analysis of Variance; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Diagnosis, Diffe | 2019 |
3D high-resolution imaging of 2-hydroxyglutarate in glioma patients using DRAG-EPSI at 3T in vivo.
Topics: Acoustics; Adult; Algorithms; Astrocytoma; Brain; Brain Mapping; Brain Neoplasms; Contrast Media; Ec | 2019 |
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
Topics: Animals; Brain; Brain Neoplasms; Cells, Cultured; Female; Glutarates; Humans; Isocitrate Dehydrogena | 2013 |
Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity.
Topics: Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Glutarates; Humans; Immunoprecipitation; Isoci | 2014 |
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome.
Topics: Cell Line, Tumor; Dipeptides; Glioma; Glutarates; Humans; Isocitrate Dehydrogenase; Metabolome; Muta | 2011 |