alpha-hydroxyglutarate has been researched along with Acquired Metabolic Diseases, Brain in 5 studies
2-hydroxyglutarate : A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of 2-hydroxyglutaric acid.
2-hydroxyglutaric acid : A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The phenotype appears to include mental retardation, macrocephaly, hypotonia, seizures, and involuntary movements, although neurologic and systemic manifestations of the disorder varied considerably between individual patients, even within the same family." | 1.29 | D-2-hydroxyglutaric aciduria. ( Bowe, C; Curry, CJ; Duran, M; Holmes, B; Jakobs, C; Nyhan, WL; Shelton, GD; Sweetman, L; Vance, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moroni, I | 1 |
| Bugiani, M | 1 |
| D'Incerti, L | 1 |
| Maccagnano, C | 1 |
| Rimoldi, M | 1 |
| Bissola, L | 1 |
| Pollo, B | 1 |
| Finocchiaro, G | 1 |
| Uziel, G | 1 |
| Craigen, WJ | 1 |
| Jakobs, C | 3 |
| Sekul, EA | 1 |
| Levy, ML | 1 |
| Gibson, KM | 1 |
| Butler, IJ | 1 |
| Herman, GE | 1 |
| Wanders, RJ | 1 |
| Mooyer, P | 1 |
| Hoffmann, GF | 1 |
| Holmes, B | 2 |
| Mitchell, L | 1 |
| Becker, G | 1 |
| Hartung, HP | 1 |
| Nyhan, WL | 2 |
| Shelton, GD | 1 |
| Bowe, C | 1 |
| Curry, CJ | 1 |
| Vance, C | 1 |
| Duran, M | 1 |
| Sweetman, L | 1 |
1 review available for alpha-hydroxyglutarate and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
L-2-hydroxyglutaric aciduria and brain malignant tumors: a predisposing condition?
Topics: Adolescent; Adult; Astrocytoma; Brain Diseases, Metabolic; Brain Neoplasms; Cerebellar Ataxia; Child | 2004 |
4 other studies available for alpha-hydroxyglutarate and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
D-2-hydroxyglutaric aciduria in neonate with seizures and CNS dysfunction.
Topics: Basal Ganglia Diseases; Blindness; Brain Diseases, Metabolic; Chromosome Aberrations; Chromosome Dis | 1994 |
D-2-hydroxyglutaric acidaemia: identification of a new enzyme, D-2-hydroxyglutarate dehydrogenase, localized in mitochondria.
Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; F | 1995 |
Organic acids in cerebrospinal fluid and plasma of patients with L-2-hydroxyglutaric aciduria.
Topics: Brain Diseases, Metabolic; Carboxylic Acids; Glutarates; Humans; Metabolism, Inborn Errors | 1995 |
D-2-hydroxyglutaric aciduria.
Topics: Animals; Biopsy; Brain Diseases, Metabolic; Child; Child, Preschool; Dog Diseases; Dogs; Female; Gas | 1995 |