alpha-cyperone has been researched along with Osteoarthritis* in 1 studies
1 other study(ies) available for alpha-cyperone and Osteoarthritis
Article | Year |
---|---|
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Inflammation and extracellular matrix (ECM) degradation have been implicated in the pathological process of osteoarthritis (OA). α-Cyperone is the main active component of the traditional Chinese medicine Topics: Animals; Anti-Inflammatory Agents; Chondrocytes; Cyperus; Down-Regulation; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Inflammation; Interleukin-1beta; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Naphthalenes; NF-kappa B; Osteoarthritis; Rats; Signal Transduction | 2021 |