alpha-cyano-4-hydroxycinnamate has been researched along with Pancreatic Neoplasms in 3 studies
alpha-cyano-4-hydroxycinnamate: specific inhibitor of pyruvate transport in rat liver mitochondria & human erythrocytes; structure
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we evaluated in pancreatic cancer cells metformin, which blocks oxidative phosphorylation, in combination with α-cyano-4-hydroxycinnamate, which has been reported to inhibit the export of lactate from the cytosol." | 1.48 | α-cyano-4-hydroxycinnamate impairs pancreatic cancer cells by stimulating the p38 signaling pathway. ( Kerndl, H; Kumstel, S; Schönrogge, M; Vollmar, B; Zechner, D; Zhang, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schönrogge, M | 1 |
| Kerndl, H | 1 |
| Zhang, X | 1 |
| Kumstel, S | 1 |
| Vollmar, B | 1 |
| Zechner, D | 1 |
| McClenaghan, NH | 1 |
| Flatt, PR | 1 |
| Best, L | 1 |
| Trebilcock, R | 1 |
| Tomlinson, S | 1 |
3 other studies available for alpha-cyano-4-hydroxycinnamate and Pancreatic Neoplasms
| Article | Year |
|---|---|
α-cyano-4-hydroxycinnamate impairs pancreatic cancer cells by stimulating the p38 signaling pathway.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Coumaric Acids; Hexokinase; | 2018 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; D | 2000 |
Lactate transport in insulin-secreting beta-cells: contrast between rat islets and HIT-T15 insulinoma cells.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Biological Transport; Carrier Proteins; Cells, | 1992 |