alpha-cyano-4-hydroxycinnamate has been researched along with Brain Ischemia in 4 studies
alpha-cyano-4-hydroxycinnamate: specific inhibitor of pyruvate transport in rat liver mitochondria & human erythrocytes; structure
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models." | 5.31 | Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001) |
| " To test the role of lactate as an aerobic energy substrate postischemia in vivo, we employed the cardiac-arrest-induced transient global cerebral ischemia (TGI) rat model and the monocarboxylate transporter inhibitor alpha-cyano-4-hydroxycinnamate (4-CIN)." | 3.71 | Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia. ( Miller, JJ; Payne, RS; Rigor, BM; Schurr, A; Tseng, MT, 2001) |
| "In vivo models of cerebral ischemia pose a conceptual challenge when compared to in vitro models." | 1.31 | Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. ( Miller, JJ; Payne, RS; Schurr, A; Tseng, MT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, JP | 1 |
| Drewes, LR | 1 |
| Phillis, JW | 1 |
| Ren, J | 1 |
| O'Regan, MH | 1 |
| Schurr, A | 2 |
| Payne, RS | 2 |
| Miller, JJ | 2 |
| Tseng, MT | 2 |
| Rigor, BM | 1 |
4 other studies available for alpha-cyano-4-hydroxycinnamate and Brain Ischemia
| Article | Year |
|---|---|
Modulation of monocarboxylic acid transporter-1 kinetic function by the cAMP signaling pathway in rat brain endothelial cells.
Topics: Animals; Brain; Brain Ischemia; Calibration; Colforsin; Coumaric Acids; Cyclic AMP; Cytoplasm; Endot | 2006 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease | 2001 |
Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Carrier Proteins; Coumaric Acids; Energy Metabolism; H | 2001 |
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticostero | 2001 |