alpha-chymotrypsin has been researched along with Sprains-and-Strains* in 7 studies
3 trial(s) available for alpha-chymotrypsin and Sprains-and-Strains
Article | Year |
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A comparative study of the management of ankle sprains.
Topics: Adult; Ankle Injuries; Anti-Inflammatory Agents; Bandages; Casts, Surgical; Chymotrypsin; Drug Combinations; Humans; Male; Sprains and Strains; Trypsin | 1983 |
The quantitative evaluation of the use of oral proteolytic enzymes in the treatment of sprained ankles.
A double-blind trial was carried out on 50 patients with soft-tissue ankle injuries. The treated group was given proteolytic enzymes (Chymoral) by mouth while the untreated group was given enteric-coated lactose tablets. Both groups received identical supportive therapy for their injuries. No statistically significant difference in swelling, bruising and function between the 2 groups in the measurements of volume and allied parameters was found. No side effects were noted. The results suggest that the use of Chymoral in this type of injury is not indicated. Topics: Adolescent; Adult; Ankle Injuries; Bandages; Chymotrypsin; Contusions; Edema; Female; Humans; Male; Movement; Sprains and Strains; Trypsin | 1975 |
Trial of Chymoral in professional footballers.
Topics: Administration, Oral; Athletic Injuries; Chymotrypsin; Clinical Trials as Topic; Edema; Hematoma; Humans; Male; Placebos; Sprains and Strains; Trypsin | 1970 |
4 other study(ies) available for alpha-chymotrypsin and Sprains-and-Strains
Article | Year |
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An inhibitor of the chymotrypsin-like activity of the proteasome (PSI) induces similar morphological changes in various cell lines.
Different established cell lines (SK-v human keratinocytes, B16F10 mouse melanoma, Muntjac fibroblasts, 3T3 mouse fibroblasts, CLV human fibroblasts) as well as primary cultures of mouse fibroblasts and giant cells were treated with N-benzyloxycarbonyl-Ile-Glu(O-t-butyl)-Ala-leucinal (proteasome inhibitor, PSI), a specific inhibitor of the chymotrypsin-like activity of the proteasome. PSI induced well characterized morphological changes in all cell lines studied, including vacuolization and accumulation of perinuclear aggregates, as detected by amido black staining. Together with previous reports on HeLa cells, the present findings support the hypothesis that ubiquitin- and proteasome-dependent proteolysis does not occur randomly in the entire cell, but it is concentrated in a well defined perinuclear region, the proteolytic center. Topics: Animals; Cell Line; Cell Nucleus; Chymotrypsin; Cysteine Endopeptidases; Histocytochemistry; Humans; Mice; Multienzyme Complexes; Organelles; Proteasome Endopeptidase Complex; Sprains and Strains; Tumor Cells, Cultured; Vacuoles | 1997 |
[The treatment of sprains and superficial phlebitis with a pommade of synthesized heparinoid base and alpha-chymotrypsin. Personal experience over 2 years with 85 patients].
Topics: Chymotrypsin; Heparinoids; Humans; Middle Aged; Phlebitis; Sprains and Strains | 1969 |
[Treatment of injuries with orally administered Varidase as compared to Chymoral and Tanderil].
Topics: Adolescent; Adult; Chymotrypsin; Contusions; Female; Hematoma; Humans; Male; Middle Aged; Oxyphenbutazone; Sprains and Strains; Streptodornase and Streptokinase; Tablets; Trypsin | 1968 |
THERMOGRAPHY IN TRAUMA.
Topics: Anti-Inflammatory Agents; Arthritis; Body Temperature; Burns; Chymotrypsin; Infrared Rays; Oxyphenbutazone; Photography; Skin; Sprains and Strains; Thermography; Wound Healing; Wounds and Injuries | 1964 |