alpha-chymotrypsin and Fatty-Liver

To compare liver proteolysis and proteasome activation in steatotic liver grafts conserved in University of Wisconsin (UW) and Institut Georges Lopez-1 (IGL-1) solutions.. Fatty liver grafts from male obese Zücker rats were conserved in UW and IGL-1 solutions for 24 h at 4 °Cand subjected to ". Our comparison of these two preservation solutions suggests that IGL-1 helps to prevent ATP breakdown more effectively than UW and subsequently achieves a higher UPS inhibition and reduced liver proteolysis.

Topics: Adenosine; Allopurinol; Animals; Apoptosis; Autophagy; Chromatography, High Pressure Liquid; Chymotrypsin; Fatty Liver; Glutathione; Graft Survival; Homozygote; Inflammation; Insulin; Liver; Liver Transplantation; Male; Mitochondria; Organ Preservation; Organ Preservation Solutions; Perfusion; Proteasome Endopeptidase Complex; Proteolysis; Raffinose; Rats; Rats, Zucker

Topics: Aged; Alcoholism; Biopsy, Needle; Cholecystokinin; Chymotrypsin; Drainage; Duodenum; Eating; Fatty Liver; Feces; Female; Humans; Lipid Metabolism; Lipids; Liver; Liver Cirrhosis; Malabsorption Syndromes; Male; Middle Aged; Pancreas; Pancreatic Diseases; Secretin

Topics: Amylases; Animal Feed; Animals; Arginase; Blood Urea Nitrogen; Chymotrypsin; Dietary Carbohydrates; Dietary Proteins; Digestion; DNA; Fatty Liver; Geese; Glucosephosphate Dehydrogenase; Intestine, Small; Ketone Oxidoreductases; Kidney; Liver; Nitrogen; Pancreas; Phosphogluconate Dehydrogenase; Poultry Diseases; RNA; Trypsin; Uric Acid; Xanthines

Topics: Antifibrinolytic Agents; Blood Platelets; Cholestasis; Chymotrypsin; Fatty Liver; Fibrinolysin; Hepatitis; Humans; Hypersplenism; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Trypsin Inhibitors

Topics: Alcoholism; Amylases; Anemia, Hemolytic; Cholecystokinin; Chymotrypsin; Clinical Enzyme Tests; Fatty Liver; Humans; Hyperlipidemias; Jaundice; Pancreas; Secretin; Trypsin