alpha-chymotrypsin and Cholesteatoma

alpha-chymotrypsin has been researched along with Cholesteatoma* in 3 studies

Other Studies

3 other study(ies) available for alpha-chymotrypsin and Cholesteatoma

ArticleYear
Isolation and characterization of trypsin-like and chymotrypsin-like proteinases from human cholesteatoma.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1994, Volume: 251, Issue:1

    The mast-cell-specific proteolytic enzymes tryptase and chymase were identified in and isolated from cholesteatoma in a ratio similar to that found in human skin. We assume that this ratio reflects a similar distribution of tryptase-containing and tryptase/chymase-containing mast cells in both these tissues. It seems conceivable that mechanisms able to trigger excessive and/or continuous mast cell degranulation in the middle ear might be causative for the formation of cholesteatoma either directly or via primed chronic inflammatory reactions. By their ability to amplify degranulation of mast cells, mast cell proteinases, in particular chymase, may contribute to the chain of events leading to the formation of cholesteatoma.

    Topics: Cell Degranulation; Cholesteatoma; Chymases; Chymotrypsin; Humans; Mast Cells; Palatine Tonsil; Pancreatic Elastase; Protease Inhibitors; Serine Endopeptidases; Skin; Species Specificity; Trypsin; Tryptases

1994
[The role of enzyme therapy in increasing the sanitizing effect of antibiotics in the treatment of chronic purulent otitis media with cholesteatoma].
    Antibiotiki, 1974, Volume: 19, Issue:4

    Topics: Chloramphenicol; Cholesteatoma; Chronic Disease; Chymotrypsin; Deoxyribonucleases; Drug Therapy, Combination; Erythromycin Ethylsuccinate; Humans; Hyaluronoglucosaminidase; Neomycin; Otitis Media; Streptomycin; Trypsin

1974
Management of atelectatic middle ear.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1969, Volume: 89, Issue:1

    Topics: Adult; Child; Cholesteatoma; Chymotrypsin; Ear, Middle; Eustachian Tube; Humans; Male; Pulmonary Atelectasis

1969