alpha-aminopyridine has been researched along with Trypanosomiasis, African in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hammarström, LG; Lundbäck, T; Rottenberg, ME; Sjöberg, B; Svensson, R; Vodnala, SK | 1 |
| Bayliss, T; Brand, S; Brenk, R; Frearson, JA; Gilbert, IH; McElroy, SP; Mpamhanga, C; Norval, S; Read, KD; Robinson, DA; Smith, VC; Stojanovski, L; Torrie, LS; Wyatt, PG | 1 |
| Brand, S; Brenk, R; Fairlamb, AH; Ferguson, MA; Frearson, JA; Gilbert, IH; Hallyburton, I; Harrison, JR; McElroy, SP; Norcross, NR; Norval, S; Read, KD; Robinson, DA; Scullion, P; Simeons, FR; Smith, VC; Stojanovski, L; Thompson, S; Torrie, LS; van Aalten, D; Wyatt, PG | 1 |
| Mackey, ZB; Ramsey, AC; Santos, WL; Valenciano, AL | 1 |
| Cross, GA | 1 |
| Brand, S; Brannigan, JA; Brenk, R; Cleghorn, LA; Fairlamb, AH; Ferguson, MA; Frearson, JA; Gilbert, IH; Guther, ML; Hallyburton, I; Hodgkinson, M; Hui, R; McElroy, SP; Mpamhanga, CP; Price, HP; Qiu, W; Raimi, OG; Read, KD; Robinson, DA; Smid, O; Smith, DF; Stojanovski, L; Torrie, LS; van Aalten, DM; Wilkinson, AJ; Wyatt, PG | 1 |
| Bayliss, T; Brand, S; Brenk, R; Cleghorn, LA; Fairlamb, AH; Ferguson, MA; Frearson, JA; Gilbert, IH; Hallyburton, I; Harrison, JR; McElroy, SP; Norcross, NR; Norval, S; Read, KD; Robinson, DA; Smith, VC; Spinks, D; Stojanovski, L; Torrie, LS; Wyatt, PG | 1 |
7 other study(ies) available for alpha-aminopyridine and Trypanosomiasis, African
| Article | Year |
|---|---|
In vitro and in vivo activities of 2-aminopyrazines and 2-aminopyridines in experimental models of human African trypanosomiasis.
Topics: Aminopyridines; Animals; Benzopyrans; Cell Line; Humans; Mice; Mice, Inbred C57BL; Piperidines; Pyrazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2013 |
Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors.
Topics: Acyltransferases; Aminopyridines; Animals; Brain; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Mice; Sulfonamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.
Topics: Acyltransferases; Aminopyridines; Animals; Blood-Brain Barrier; Central Nervous System; Female; Humans; Inhibitory Concentration 50; Mice; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Discovery and antiparasitic activity of AZ960 as a Trypanosoma brucei ERK8 inhibitor.
Topics: Aminopyridines; Drug Discovery; Extracellular Signal-Regulated MAP Kinases; Humans; Protein Kinase Inhibitors; Pyrazoles; Recombinant Proteins; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2016 |
Drug discovery: Fat-free proteins kill parasites.
Topics: Acyltransferases; Aminopyridines; Animals; Antiparasitic Agents; Enzyme Inhibitors; Humans; Mice; Sulfonamides; Trypanosoma brucei brucei; Trypanosomiasis, African | 2010 |
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Topics: Acyltransferases; Aminopyridines; Animals; Antiparasitic Agents; Enzyme Assays; Enzyme Inhibitors; Female; Humans; Mice; Molecular Structure; Pyrazoles; Rats; Sulfonamides; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 2010 |
Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.
Topics: Acyltransferases; Administration, Oral; Aminopyridines; Animals; Cell Line; Cell Survival; Crystallography, X-Ray; Databases, Factual; Humans; Models, Molecular; Molecular Conformation; Parasitic Sensitivity Tests; Structure-Activity Relationship; Sulfonamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2012 |