alpha-aminopyridine has been researched along with Schizophrenia in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Ffytche, D; Gilleen, J; Kerins, S; Lahu, G; Mehta, MA; Nottage, J; Ogrinc, F; Shergill, SS; Tsai, M; Uz, T; Valdearenas, L; Williams, SC; Yakub, F | 1 |
| Gilleen, J; Hawkins, PC; Livingston, NR; Mehta, MA; Shergill, SS; Valdearenas, L; Ye, R | 1 |
| Davison, C; Farah, Y; Gilleen, J; Kerins, S; Lahu, G; Mehta, MA; Ogrinc, F; Reichenberg, A; Shergill, SS; Tsai, M; Uz, T; Valdearenas, L; Williams, SC | 1 |
| Ballard, TM; Hernandez, MC; Hoffmann, T; Knoflach, F; Malherbe, P; Porter, RH; Schnider, P; Spooren, W; Steward, L; Wettstein, JG | 1 |
| Balsam, PD; Fairhurst, S; Kandel, ER; Kellendonk, C; Lipatova, O; Richards, V; Simpson, EH; Ward, RD | 1 |
| Cosi, C; Newman-Tancredi, A; Rollet, K; Tesori, V; Waget, A | 1 |
| Chari, S; Deth, RC; DuRand, CJ; Kotb, M; Kramer, ML; Liu, D; Nagata, M; Ouellette, D; Sharma, A; Shim, S; Tan, W; Wick, PF | 1 |
3 trial(s) available for alpha-aminopyridine and Schizophrenia
| Article | Year |
|---|---|
The effects of roflumilast, a phosphodiesterase type-4 inhibitor, on EEG biomarkers in schizophrenia: A randomised controlled trial.
Topics: Adult; Aminopyridines; Benzamides; Cognition; Cognitive Dysfunction; Cross-Over Studies; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Double-Blind Method; Drug Monitoring; Electroencephalography; Evoked Potentials; Female; Humans; Male; Mental Processes; Phosphodiesterase 4 Inhibitors; Psychiatric Status Rating Scales; Schizophrenia; Treatment Outcome | 2021 |
Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia.
Topics: Adult; Aged; Aminopyridines; Benzamides; Cognitive Dysfunction; Cross-Over Studies; Cyclopropanes; Dorsolateral Prefrontal Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Phosphodiesterase 4 Inhibitors; Prefrontal Cortex; Schizophrenia | 2021 |
An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients.
Topics: Adult; Aminopyridines; Animals; Benzamides; Brain; Cognition; Cognition Disorders; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Humans; Male; Memory, Episodic; Memory, Short-Term; Middle Aged; Phosphodiesterase 4 Inhibitors; Prefrontal Cortex; Schizophrenia | 2021 |
4 other study(ies) available for alpha-aminopyridine and Schizophrenia
| Article | Year |
|---|---|
Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK₁ and NK₃ receptors.
Topics: Action Potentials; Amides; Aminopyridines; Animals; Antipsychotic Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Female; Gerbillinae; Guinea Pigs; HEK293 Cells; Humans; In Vitro Techniques; Inositol; Ligands; Macaca fascicularis; Male; Mesencephalon; Mice; Neurokinin-1 Receptor Antagonists; Neurons; Phosphorylation; Pyridines; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Schizophrenia; Substance P; Substantia Nigra | 2011 |
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia.
Topics: Affective Symptoms; Aminopyridines; Analysis of Variance; Animals; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Gene Expression; Indoles; Mice; Mice, Transgenic; Motivation; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Reward; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Up-Regulation | 2011 |
Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo: role of 5-HT1A receptor activation.
Topics: Aminopyridines; Animals; Antipsychotic Agents; Aripiprazole; Clozapine; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Agonists; Haloperidol; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Piperazines; Piperidines; Pyridines; Quinolones; Receptor, Serotonin, 5-HT1A; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Thiazoles | 2005 |
D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia.
Topics: Amino Acid Sequence; Aminopyridines; Animals; Benzazepines; Binding Sites; Carbon Radioisotopes; CHO Cells; Clozapine; Cricetinae; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Formates; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methionine; Mutagenesis, Site-Directed; Neuroblastoma; Phospholipids; Phosphorylation; Piperidines; Psychotic Disorders; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; S-Adenosylmethionine; Salicylamides; Schizophrenia; Transfection; Tumor Cells, Cultured | 1999 |