Page last updated: 2024-08-21

alpha-aminopyridine and Prostatic Neoplasms

alpha-aminopyridine has been researched along with Prostatic Neoplasms in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's7 (50.00)24.3611
2020's6 (42.86)2.80

Authors

AuthorsStudies
Ahmadi, N; Butler, LM; Centenera, MM; Horvath, LG; Joshua, AM; Kench, J; Mahon, KL; Scheinberg, T; Sebastian, L; Stockler, M; Stricker, P; Thanigasalam, R; Woo, H1
André, T; Bay, JO; Bouleuc, C; Hervé, L; Magné, N; Penel, N; Rodrigues, M; Sabatier, R; Thiery-Vuillemin, A; Wislez, M1
Chen, S; Lin, D; Liu, Y; Peng, H; Wang, J; Wang, L; Wang, Y; Xiao, L; Xu, Y; Yang, K1
Borre, M; Cieza-Borrella, C; Dagnaes-Hansen, F; Eeles, R; Haldrup, J; Hedensted, S; Jakobsson, ME; Kote-Jarai, Z; Norgaard, M; Olsen, JV; Riedel, M; Sorensen, KD; Strand, SH; Thomsen, M; Ulhoi, BP1
Baird, AM; Bozkurt, E; Debelec Butuner, B; Finn, SP; Gray, SG; Kantarci, AG; Kotmakci, M; Oner, E1
Abdel-Wahab, BA; Albarqi, HA; Ali, FEM; Hassanein, EHM; Walbi, IA1
Huang, X; Li, M; Liao, W; Liu, B; Liu, J; Yin, Y; Zhu, R1
Burton, EA; Chartier, S; Habets, G; Jimenez-Andrade, JM; Lin, PS; Mantyh, PW; Thompson, ML; Tsai, J; West, BL1
Dai, Y; Siemann, DW2
Fiedler, W; Schultze, A1
Cooke, I; Goodchild, CS; Kolosov, A; Williams, ED1
Gao, X; Jia, S; Lee, SH; Loda, M; Maira, SM; Roberts, TM; Signoretti, S; Stack, EC; Wu, X; Zhao, JJ1
Agus, DB; Breslow, R; Butler, LM; Cordon-Cardo, C; Drobnjak, M; Higgins, B; Kutko, MC; LaQuaglia, MP; Marks, PA; Richon, VM; Rifkind, RA; Scher, HI; Tolentino, TR; Webb, Y1

Reviews

2 review(s) available for alpha-aminopyridine and Prostatic Neoplasms

ArticleYear
[2019 international oncology news: A compendium].
    Bulletin du cancer, 2020, Volume: 107, Issue:2

    Topics: Aminopyridines; Breast Neoplasms; Clinical Trials as Topic; Digestive System Neoplasms; Female; Genital Neoplasms, Female; Humans; Lung Neoplasms; Male; Molecular Targeted Therapy; Neoplasms; Neoplasms, Unknown Primary; Prostatic Neoplasms; Purines

2020
Clinical importance and potential use of small molecule inhibitors of focal adhesion kinase.
    Anti-cancer agents in medicinal chemistry, 2011, Volume: 11, Issue:7

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hydroxamic Acids; Indoles; Male; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Pancreatic Neoplasms; Prostatic Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides

2011

Other Studies

12 other study(ies) available for alpha-aminopyridine and Prostatic Neoplasms

ArticleYear
Pharmacodynamics effects of CDK4/6 inhibitor LEE011 (ribociclib) in high-risk, localised prostate cancer: a study protocol for a randomised controlled phase II trial (LEEP study: LEE011 in high-risk, localised Prostate cancer).
    BMJ open, 2020, 01-26, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Aminopyridines; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Proliferation; Clinical Trials, Phase II as Topic; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Disease-Free Survival; E2F Transcription Factors; Humans; Kallikreins; Male; Neoadjuvant Therapy; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Purines; Randomized Controlled Trials as Topic; Research Design

2020
PKMYT1 is associated with prostate cancer malignancy and may serve as a therapeutic target.
    Gene, 2020, Jun-20, Volume: 744

    Topics: Aminopyridines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclin E; Humans; Male; Membrane Proteins; Morpholines; Oncogene Proteins; Oxazines; Prognosis; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Pyrimidines

2020
FRMD6 has tumor suppressor functions in prostate cancer.
    Oncogene, 2021, Volume: 40, Issue:4

    Topics: Aged; Aminopyridines; Animals; Cell Proliferation; Cytoskeletal Proteins; DNA Methylation; Down-Regulation; Hippo Signaling Pathway; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Middle Aged; Prognosis; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Serine-Threonine Kinases; PTEN Phosphohydrolase; Tumor Suppressor Proteins

2021
Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids.
    Journal of nanobiotechnology, 2021, Mar-08, Volume: 19, Issue:1

    Topics: Aminopyridines; Cations; Cell Line, Tumor; Cell Survival; Gene Silencing; Histone Demethylases; Humans; Hydrazones; Lipids; Male; Nanoparticles; Particle Size; Prostate; Prostatic Neoplasms; Receptor, EphA2; RNA, Small Interfering; Transfection

2021
Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO-1, NQO1 signaling.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 151

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cisplatin; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Heme Oxygenase (Decyclizing); Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; NF-kappa B; Prostatic Neoplasms; Rats; Rats, Wistar; Signal Transduction

2021
JIB‑04 induces cell apoptosis via activation of the p53/Bcl‑2/caspase pathway in MHCC97H and HepG2 cells.
    Oncology reports, 2018, Volume: 40, Issue:6

    Topics: Aminopyridines; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hydrazones; Lung Neoplasms; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Suppressor Protein p53

2018
Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer.
    Pain, 2015, Volume: 156, Issue:9

    Topics: Aminopyridines; Analgesics; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Dogs; Formaldehyde; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pain; Pain Measurement; Prostatic Neoplasms; Protein Kinases; Pyrroles; Rats; Rats, Sprague-Dawley

2015
BMS-777607, a small-molecule met kinase inhibitor, suppresses hepatocyte growth factor-stimulated prostate cancer metastatic phenotype in vitro.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:6

    Topics: Aminopyridines; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Hepatocyte Growth Factor; Humans; Male; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridones; Signal Transduction; Small Molecule Libraries

2010
Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607.
    BMC cancer, 2012, May-28, Volume: 12

    Topics: Aminopyridines; Antibodies, Neutralizing; Autocrine Communication; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Male; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridones; RNA, Messenger; Signal Transduction

2012
Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:11

    Topics: Aminopyridines; Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Hyperalgesia; Male; Morphine; Pain; Prostatic Neoplasms; Rats; Rats, Wistar

2012
Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.
    Cancer discovery, 2013, Volume: 3, Issue:1

    Topics: Aminopyridines; Androgen Receptor Antagonists; Animals; Antineoplastic Agents; Benzamides; Benzimidazoles; Castration; Imidazoles; Male; MAP Kinase Kinase Kinases; Mice; Mice, Transgenic; Morpholines; Nitriles; Phenylthiohydantoin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Quinolines; Testosterone

2013
Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:4

    Topics: Acetylation; Aminopyridines; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Line, Transformed; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Models, Animal; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostate-Specific Antigen; Prostatic Neoplasms; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001