Page last updated: 2024-08-21

alpha-aminopyridine and Pneumonia

alpha-aminopyridine has been researched along with Pneumonia in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (20.00)29.6817
2010's12 (60.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Keechilat, P; Kunoor, A; Pushpa Ragahavan, R; Rajendran, A1
Neeland, MR; Ranganathan, S; Shanthikumar, S1
Kawasaki, T; Kumagai, J; Miyazaki, Y; Okayasu, K1
Arriola, E; Monzonís, X1
Harwood, KH; Jarnicki, A; McQuade, RM; Schneider-Futschik, EK1
Covel, J; Fierer, J; Kapoor, M; Okamoto, S; Shaw, KJ; Soltow, QA; Trzoss, M; Viriyakosol, S1
Adamkov, M; Balentova, S; Calkovska, A; Kolomaznik, M; Kosutova, P; Mikolka, P; Mokra, D1
Biller, H; Hohlfeld, JM; Holz, O; Janssen, O; Krug, N; Lavae-Mokhtari, B; Schaumann, F; Welker, L; Winkler, C1
Etori, M; Goto, T; Hirahara, K; Maeda, H; Mikkaichi, T; Mizukami, K; Morimoto, K; Nakamura, S; Sogawa, Y; Suzuki, O; Takagi, N; Tsuchida, H; Yoshino, T1
Becker, P; Greeff, O; Xaba, SN1
Bury, A; Konrad, FM; Ngamsri, KC; Reutershan, J; Schick, MA1
Eckle, T; Eltzschig, HK; Grenz, A; Laucher, S1
Beume, R; Braun, A; Hoymann, HG; Korolewitz, R; Krug, N; Muller, M; Wollin, L1
Bahra, P; Banner, KH; Dale, N; Freeman, MS; Hardaker, EL; Poll, C; Raza, F1
Iwata, M; Kobayashi, M; Kubo, S; Ohtsu, Y; Shimizu, Y; Takahashi, K1
Boulet, LP; Bredenbröker, D; Côté, J; Deschesnes, F; Duong, M; Gauvreau, GM; Killian, KJ; Milot, J; O'Byrne, PM; Schmid-Wirlitsch, C; Strinich, T; Watson, RM1
Iwata, M; Kobayashi, M; Kubo, S; Miyata, K; Shimizu, Y; Takahashi, K1
Konrad, FM; Reutershan, J; Stark, S; Vollmer, I; Witte, E1
Vignola, AM1
Beume, R; Bundschuh, DS; Marx, D; Wohlsen, A; Wollin, L1

Reviews

2 review(s) available for alpha-aminopyridine and Pneumonia

ArticleYear
Anti-Inflammatory Influences of Cystic Fibrosis Transmembrane Conductance Regulator Drugs on Lung Inflammation in Cystic Fibrosis.
    International journal of molecular sciences, 2021, Jul-16, Volume: 22, Issue:14

    Topics: Aminophenols; Aminopyridines; Anti-Inflammatory Agents; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Indoles; Inflammation; Ion Transport; Lung; Macrophages; Pneumonia; Quinolones; Signal Transduction

2021
PDE4 inhibitors in COPD--a more selective approach to treatment.
    Respiratory medicine, 2004, Volume: 98, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminopyridines; Benzamides; Bronchodilator Agents; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Humans; Nitriles; Phosphodiesterase Inhibitors; Pneumonia; Pulmonary Disease, Chronic Obstructive; Rolipram; Theophylline; Treatment Outcome

2004

Trials

2 trial(s) available for alpha-aminopyridine and Pneumonia

ArticleYear
Low-dose endotoxin inhalation in healthy volunteers--a challenge model for early clinical drug development.
    BMC pulmonary medicine, 2013, Mar-28, Volume: 13

    Topics: Administration, Inhalation; Adolescent; Adult; Aminopyridines; Benzamides; Cyclopropanes; Dose-Response Relationship, Drug; Drug Design; Endotoxins; Female; Healthy Volunteers; Humans; Lipopolysaccharides; Male; Middle Aged; Monocytes; Neutrophils; Phosphodiesterase 4 Inhibitors; Pneumonia; Reproducibility of Results; Research Design; Sputum; Young Adult

2013
Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects.
    Respiratory research, 2011, Oct-26, Volume: 12

    Topics: Adolescent; Adult; Allergens; Aminopyridines; Asthma; Benzamides; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Phosphodiesterase 4 Inhibitors; Pneumonia; Pulmonary Eosinophilia; Young Adult

2011

Other Studies

16 other study(ies) available for alpha-aminopyridine and Pneumonia

ArticleYear
Ribociclib-associated organising pneumonia.
    BMJ case reports, 2021, Dec-20, Volume: 14, Issue:12

    Topics: Aminopyridines; Cough; Dyspnea; Humans; Middle Aged; Pneumonia; Purines

2021
Ivacaftor, not ivacaftor/lumacaftor, associated with lower pulmonary inflammation in preschool cystic fibrosis.
    Pediatric pulmonology, 2022, Volume: 57, Issue:10

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Humans; Mutation; Pneumonia; Quinolones

2022
Clinicoradiological course of abemaciclib-induced pneumonitis with histology findings.
    BMJ case reports, 2023, May-02, Volume: 16, Issue:5

    Topics: Aminopyridines; Chronic Disease; Female; Humans; Mucin-1; Neoplasm Recurrence, Local; Pneumonia

2023
Early Onset Pulmonary Toxicity With Lorlatinib in a Patient With Previous Pulmonary Toxicity From Brigatinib.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2019, Volume: 14, Issue:11

    Topics: Adenocarcinoma of Lung; Aminopyridines; Anaplastic Lymphoma Kinase; Female; Humans; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Middle Aged; Organophosphorus Compounds; Pneumonia; Prognosis; Pyrazoles; Pyrimidines

2019
APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:2

    Topics: Aminopyridines; Amphotericin B; Animals; Antifungal Agents; Coccidioides; Disease Models, Animal; Female; Fluconazole; Isoxazoles; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia; Prodrugs; Triazoles

2019
Reduction of lung inflammation, oxidative stress and apoptosis by the PDE4 inhibitor roflumilast in experimental model of acute lung injury.
    Physiological research, 2018, 12-31, Volume: 67, Issue:Suppl 4

    Topics: Acute Lung Injury; Aminopyridines; Animals; Apoptosis; Benzamides; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Female; Male; Oxidative Stress; Phosphodiesterase 4 Inhibitors; Pneumonia; Rabbits

2018
Evaluation of the therapeutic index of a novel phosphodiesterase 4B-selective inhibitor over phosphodiesterase 4D in mice.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:3

    Topics: Administration, Ophthalmic; Aminopyridines; Animals; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Gastric Emptying; Heterocyclic Compounds, 2-Ring; Humans; Leukocyte Disorders; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Neutrophils; Phenylacetates; Phosphodiesterase 4 Inhibitors; Pneumonia; Tumor Necrosis Factor-alpha

2013
Determinants, outcomes and costs of ceftriaxone v. amoxicillin-clavulanate in the treatment of community-acquired pneumonia at Witbank Hospital.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Ceftriaxone; Clavulanic Acid; Community-Acquired Infections; Drug Combinations; Female; Humans; Length of Stay; Male; Middle Aged; Pneumonia; Sex Factors; Treatment Outcome

2014
The unrecognized effects of phosphodiesterase 4 on epithelial cells in pulmonary inflammation.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aminopyridines; Animals; Benzamides; Capillary Permeability; Chemokines; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Cytoskeleton; Disease Models, Animal; Enzyme Activation; Epithelial Cells; Gene Expression; Male; Mice; Neutrophil Infiltration; Neutrophils; Phosphodiesterase 4 Inhibitors; Pneumonia; Protein Transport; Rolipram; Time Factors

2015
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:10

    Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aminopyridines; Animals; Chimera; Extravascular Lung Water; Female; Gene Expression Regulation; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pneumonia; Pulmonary Alveoli; Receptor, Adenosine A2B; Receptors, Purinergic P1; Signal Transduction; Time Factors; Ventilators, Mechanical; Xanthines

2008
Effects of the phosphodiesterase type 4 inhibitor roflumilast on early and late allergic response and airway hyperresponsiveness in Aspergillus-fumigatus-sensitized mice.
    Pharmacology, 2009, Volume: 83, Issue:3

    Topics: Aminopyridines; Animals; Antigens, Fungal; Aspergillus fumigatus; Asthma; Benzamides; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Eosinophils; Female; Leukocyte Count; Lymphocytes; Methacholine Chloride; Mice; Mice, Inbred BALB C; Neutrophils; Phosphodiesterase 4 Inhibitors; Pneumonia; Respiratory Hypersensitivity; Respiratory Mechanics

2009
Exposing rodents to a combination of tobacco smoke and lipopolysaccharide results in an exaggerated inflammatory response in the lung.
    British journal of pharmacology, 2010, Volume: 160, Issue:8

    Topics: Adrenal Cortex Hormones; Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Bronchoalveolar Lavage Fluid; Budesonide; Cyclopropanes; Disease Models, Animal; Inflammation Mediators; Lipopolysaccharides; Lung; Male; Mucus; Neutrophil Infiltration; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pneumonia; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Tobacco Smoke Pollution

2010
ASP3258, an orally active potent phosphodiesterase 4 inhibitor with low emetic activity.
    International immunopharmacology, 2011, Volume: 11, Issue:6

    Topics: Adrenergic alpha-2 Receptor Antagonists; Aminopyridines; Animals; Benzamides; Blood Cells; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Enzyme Inhibitors; Ferrets; Interleukin-4; Lipopolysaccharides; Macrophages, Alveolar; Naphthyridines; Nitriles; Pneumonia; Rats; Tumor Necrosis Factor-alpha; Vomiting

2011
Anti-neutrophilic inflammatory activity of ASP3258, a novel phosphodiesterase type 4 inhibitor.
    International immunopharmacology, 2012, Volume: 12, Issue:1

    Topics: Adult; Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Bronchoalveolar Lavage Fluid; Cells, Cultured; Chemokine CXCL1; Cyclohexanecarboxylic Acids; Cyclopropanes; Glucocorticoids; Humans; Lipopolysaccharides; Male; Naphthyridines; Neutrophils; Nitriles; Phosphodiesterase 4 Inhibitors; Pneumonia; Prednisolone; Rats; Rats, Wistar; Superoxides; Tumor Necrosis Factor-alpha

2012
Adenosine receptor A2b on hematopoietic cells mediates LPS-induced migration of PMNs into the lung interstitium.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Volume: 303, Issue:5

    Topics: Acute Lung Injury; Adenosine A2 Receptor Agonists; Aminopyridines; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cell Count; Cells, Cultured; Chemokines; Cytoskeleton; Gene Expression; Gene Expression Regulation; Humans; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Pneumonia; Receptor, Adenosine A2B; Respiratory Burst; Transendothelial and Transepithelial Migration

2012
Inhibition of airway hyperresponsiveness and pulmonary inflammation by roflumilast and other PDE4 inhibitors.
    Pulmonary pharmacology & therapeutics, 2006, Volume: 19, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Oral; Aminopyridines; Animals; Benzamides; Bronchial Spasm; Bronchoalveolar Lavage Fluid; Carboxylic Acids; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Cyclopropanes; Disease Models, Animal; Immunization; Male; Neutrophils; Nitriles; Ovalbumin; Phosphodiesterase Inhibitors; Pneumonia; Pyridines; Rats; Respiratory Hypersensitivity; Rolipram; Serotonin; Treatment Outcome; Tumor Necrosis Factor-alpha

2006