alpha-aminopyridine has been researched along with Pancreatic Neoplasms in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (55.00) | 24.3611 |
| 2020's | 9 (45.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hiramoto, M; Hirota, A; Kazama, H; Miyazaki, M; Miyazawa, K; Ogawa, M; Ota, K; Suzuki, S; Takano, N | 1 |
| Bechard, ME; Bilbao, D; Duryea, J; Kingsley, PJ; Marnett, LJ; McDonald, OG; Roberts, ER; Smalling, RV; Stauffer, SR | 1 |
| Al-Ali, R; Ameziane, N; Bauer, P; Junghanss, C; Kong, W; Krake, S; Lerch, MM; Ma, Y; Murua Escobar, H; Parveen, A; Radefeldt, M; Sekora, A; Sender, S; Weiss, FU; Zechner, D | 1 |
| Inkielewicz-Stępniak, I; Kowalski, S; Sikorski, A; Tesmar, A | 1 |
| Amen, A; Bronsert, P; Brunner, TB; Follo, M; Grosu, AL; Mekawy, M; Mohamed, AA; Mostafa, H; Thomsen, A; Zamboglou, C | 1 |
| Arnes, L; Bravo, MC; Erler, JT; Horton, ER; Hwang, CI; Jackstadt, R; Jensen, ARD; Karim, SA; Laitala, A; Maltese, G; Morton, JP; Nielsen, SR; Rafaeva, M; Reuten, R; Sansom, OJ; Strøbech, JE; Tuveson, DA | 1 |
| Aboukameel, A; Al-Hallak, MN; Azmi, AS; Baloglu, E; Beydoun, R; Dyson, G; El-Rayes, BF; Kim, SH; Landesman, Y; Li, Y; Mohammad, RM; Mpilla, GB; Philip, PA; Senapedis, WT; Uddin, MH; Viola, NT; Wagner, KU | 1 |
| Bannas, P; Beumer, N; Bokemeyer, C; Goekkurt, E; Iglauer, P; Imbusch, CD; Loges, S; Simon, R; Velthaus, JL | 1 |
| Aboukameel, A; Azmi, AS; Baloglu, E; Landesman, Y; Li, Y; Mohammad, RM; Muqbil, I; Philip, PA; Senapedis, W | 1 |
| DeNardo, DG; Fields, RC; Hegde, S; Jiang, H; Knolhoff, BL; Lee, KB; Lim, KH; Liu, X; Pachter, JA | 1 |
| Ge, Y; Guo, Y; He, M; He, Y; Li, W; Qiao, Z; Ren, S; Sun, L; Wang, X; Yu, Q | 1 |
| Hu, X; Sharma, S; Wang, MH; Yao, HP; Zeng, JY; Zhang, R; Zhou, YQ | 1 |
| Herrera Loeza, SG; Kamande, JW; Moffitt, RA; Soper, SA; Tignanelli, CJ; Torphy, RJ; Yeh, JJ | 1 |
| Hong, S; Hong, SS; Jung, KH; Kim, SJ; Ryu, YL; Shin, S; Son, MK; Yan, HH | 1 |
| Alagesan, B; Bardeesy, N; Benes, CH; Contino, G; Corcoran, RB; Deshpande, V; Engelman, J; Guimaraes, AR; Hezel, AF; Loda, M; Weissleder, R; Wojtkiewicz, GR; Wong, KK | 1 |
| He, T; Zhao, B | 1 |
| DeNardo, DG; Hawkins, WG; Hegde, S; Herndon, JM; Jiang, H; Knolhoff, BL; Meyer, MA; Nywening, TM; Pachter, JA; Shapiro, IM; Wang-Gillam, A; Weaver, DT; Zhu, Y | 1 |
| He, M; Jiang, X; Kuai, Q; Li, C; Li, W; Qiao, Z; Ren, S; Wang, X; Wang, Y; Yu, Q | 1 |
| Fiedler, W; Schultze, A | 1 |
| Dawson, J; Sullivan, DM; Turner, JG | 1 |
2 review(s) available for alpha-aminopyridine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Clinical importance and potential use of small molecule inhibitors of focal adhesion kinase.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hydroxamic Acids; Indoles; Male; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Pancreatic Neoplasms; Prostatic Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides | 2011 |
Nuclear export of proteins and drug resistance in cancer.
Topics: Active Transport, Cell Nucleus; Aminopyridines; Antigens, Neoplasm; Antineoplastic Agents; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Exportin 1 Protein; Fatty Acids, Unsaturated; Female; Galectin 3; Humans; Karyopherins; Ovarian Neoplasms; Pancreatic Neoplasms; Proteins; Pyrones; Pyrrolidinones; Receptors, Cytoplasmic and Nuclear | 2012 |
18 other study(ies) available for alpha-aminopyridine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Lysosome‑targeted drug combination induces multiple organelle dysfunctions and non‑canonical death in pancreatic cancer cells.
Topics: Aminopyridines; Antineoplastic Agents; Benzimidazoles; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Fingolimod Hydrochloride; Humans; Hydroxychloroquine; Lapatinib; Lysosomes; Pancreatic Neoplasms; Sphingosine 1 Phosphate Receptor Modulators | 2022 |
Aminopyridine analogs selectively target metastatic pancreatic cancer.
Topics: Aminopyridines; Carcinogenesis; Histones; Humans; Pancreatic Neoplasms; Phosphogluconate Dehydrogenase; Prodrugs | 2022 |
The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.
Topics: Aminopyridines; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Heterocyclic Compounds, 3-Ring; Humans; Morpholines; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Signal Transduction | 2022 |
Oxidovanadium(IV) Complex Disrupts Mitochondrial Membrane Potential and Induces Apoptosis in Pancreatic Cancer Cells.
Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Drug Screening Assays, Antitumor; Humans; Ligands; Membrane Potential, Mitochondrial; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Vanadium | 2021 |
FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro.
Topics: Aminopyridines; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Coculture Techniques; Collagen; Extracellular Matrix Proteins; Focal Adhesion Kinase 1; Histones; Humans; Kaplan-Meier Estimate; Neoplasm Proteins; Pancreatic Neoplasms; Pancreatic Stellate Cells; Progression-Free Survival; Protein Kinase Inhibitors; Radiation Tolerance; Radiation-Sensitizing Agents; RNA Interference; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Spheroids, Cellular; Stromal Cells; Tumor Stem Cell Assay | 2021 |
Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Female; Humans; Immune Checkpoint Inhibitors; Lactams; Lactams, Macrocyclic; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Male; Mice; Mice, Transgenic; Neutrophils; Pancreatic Neoplasms; Programmed Cell Death 1 Receptor; Pyrazoles; Tumor Microenvironment | 2021 |
PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus.
Topics: Acrylamides; Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cytokines; Drug Therapy, Combination; Everolimus; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred ICR; Mice, SCID; Neuroendocrine Tumors; Nicotinamide Phosphoribosyltransferase; p21-Activated Kinases; Pancreatic Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
Lorlatinib Induces Durable Disease Stabilization in a Pancreatic Cancer Patient with a ROS1 p.L1950F Mutation: Case Report.
Topics: Aminopyridines; Carcinoma, Non-Small-Cell Lung; Humans; Lactams; Lung Neoplasms; Mutation; Pancreatic Neoplasms; Precision Medicine; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles | 2021 |
Targeting Rho GTPase effector p21 activated kinase 4 (PAK4) suppresses p-Bad-microRNA drug resistance axis leading to inhibition of pancreatic ductal adenocarcinoma proliferation.
Topics: Acrylamides; Aminopyridines; bcl-Associated Death Protein; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cytokines; Drug Resistance, Neoplasm; Enzyme Activation; Humans; MicroRNAs; Nicotinamide Phosphoribosyltransferase; p21-Activated Kinases; Pancreatic Neoplasms; RNA, Neoplasm | 2019 |
Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Collagen; Down-Regulation; Drug Resistance, Neoplasm; Female; Fibroblasts; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mice, Inbred Strains; Pancreatic Neoplasms; Signal Transduction; Smad3 Protein; STAT3 Transcription Factor; Stromal Cells; Transforming Growth Factor beta; Xenograft Model Antitumor Assays | 2020 |
Chidamide, a novel histone deacetylase inhibitor, synergistically enhances gemcitabine cytotoxicity in pancreatic cancer cells.
Topics: Aminopyridines; Antimetabolites, Antineoplastic; Benzamides; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Pancreatic Neoplasms; Up-Regulation | 2013 |
Synergistic activities of MET/RON inhibitor BMS-777607 and mTOR inhibitor AZD8055 to polyploid cells derived from pancreatic cancer and cancer stem cells.
Topics: Aminopyridines; Apoptosis; Cell Line, Tumor; Drug Synergism; Humans; Morpholines; Neoplastic Stem Cells; Pancreatic Neoplasms; Polyploidy; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridones; Signal Transduction | 2014 |
Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Aminopyridines; Animals; Antigens, Neoplasm; Biomarkers; Cell Adhesion Molecules; DNA Mutational Analysis; DNA Primers; Epithelial Cell Adhesion Molecule; Fluorescent Antibody Technique; Humans; Mice; Microfluidic Analytical Techniques; Morpholines; Neoplastic Cells, Circulating; Pancreatic Neoplasms; Statistics, Nonparametric | 2014 |
Anticancer activity of HS-527, a novel inhibitor targeting PI3-kinase in human pancreatic cancer cells.
Topics: Aminopyridines; Angiogenesis Inhibitors; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Molecular Targeted Therapy; Neovascularization, Physiologic; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfonamides; Time Factors; Vascular Endothelial Growth Factor A | 2014 |
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzimidazoles; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Models, Animal; Drug Screening Assays, Antitumor; Drug Synergism; Erlotinib Hydrochloride; Humans; MAP Kinase Kinase Kinases; Mice, Transgenic; Morpholines; Pancreatic Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines | 2015 |
Chidamide, a histone deacetylase inhibitor, functions as a tumor inhibitor by modulating the ratio of Bax/Bcl-2 and P21 in pancreatic cancer.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Benzamides; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.
Topics: Aminopyridines; Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Cell Proliferation; Deoxycytidine; Disease Models, Animal; Disease Progression; Fibrosis; Focal Adhesion Protein-Tyrosine Kinases; Gemcitabine; Humans; Immunoblotting; Immunohistochemistry; Immunotherapy; Immunotherapy, Adoptive; Mice; Pancreatic Neoplasms; Programmed Cell Death 1 Receptor; Reverse Transcriptase Polymerase Chain Reaction; Tumor Escape; Tumor Microenvironment | 2016 |
Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation.
Topics: Aminopyridines; Benzamides; Cell Cycle Checkpoints; Cell Line, Tumor; Gene Knockdown Techniques; Humans; Leupeptins; Myeloid Cell Leukemia Sequence 1 Protein; Oxidative Phosphorylation; Oxygen Consumption; Pancreatic Neoplasms; Proteasome Endopeptidase Complex; Proteolysis; Ubiquitin | 2016 |