alpha-aminopyridine has been researched along with Osteogenic Sarcoma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H; Wang, D | 1 |
| Hu, X; Jian, C; Li, D; Li, P; Li, Y; Li, Z; Yi, W; Yu, A; Yuan, Y; Zhao, Y | 1 |
| Ferreira, LP; Gaspar, VM; Mano, JF; Monteiro, MV | 1 |
| Crosby, MR; Hudson, WA; Laoharawee, K; Largaespada, DA; Larsson, AT; Mills, LJ; Moriarity, BS; Osum, SH; Peterson, JJ; Pomeroy, EJ; Rahrmann, EP; Rathe, SK; Slipek, NJ; Smeester, BA; Stratton, N; Wang, M; Williams, KB; Yamamoto, K | 1 |
| Bennett, CE; Cam, H; Coss, CC; Gardner, HL; Guttridge, DC; Hariharan, S; Houghton, P; LeBlanc, AK; Lin, J; Ling, Y; London, CA; Mo, X; Phelps, MA; Ren, L; Roberts, R; Xiao, H; Yu, PY | 1 |
| Bavelloni, A; Blalock, W; Cocco, L; Faenza, I; Focaccia, E; Orsini, A; Piazzi, M; Ramazzotti, G | 1 |
| Lee, BH; Lee, SY; Ryu, PD | 1 |
| Liu, B; Peng, D; Wu, Y; Zhou, Y | 1 |
| Akin, D; Dunn, WA; Habibzadegah-Tari, P; Horenstein, N; Kim, JS; Law, B; Li, M; Ostrov, D; Wang, SK; Yin, XM | 1 |
| Avnet, S; Baldini, N; Di Pompo, G; Lattanzi, G; Mai, A; Rotili, D; Salerno, M; Valente, S; Zwergel, C | 1 |
| Akiyama, R; Anderson, JL; Denny, CT; Federman, N; Park, A; Tap, WD | 1 |
11 other study(ies) available for alpha-aminopyridine and Osteogenic Sarcoma
| Article | Year |
|---|---|
Abemaciclib is synergistic with doxorubicin in osteosarcoma pre-clinical models via inhibition of CDK4/6-Cyclin D-Rb pathway.
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin D; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Doxorubicin; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Mice, SCID; Osteosarcoma; Retinoblastoma Protein; Xenograft Model Antitumor Assays | 2022 |
Chidamide augment sorafenib-derived anti-tumor activities in human osteosarcoma cells lines and xenograft mouse model.
Topics: Aminopyridines; Animals; Benzamides; Bone Neoplasms; Cell Line, Tumor; Heterografts; Histone Deacetylase Inhibitors; Humans; Mice; Osteosarcoma; Sorafenib | 2022 |
Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response.
Topics: Aminopyridines; Biomimetic Materials; Bone Neoplasms; Cell Aggregation; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Matrix; Humans; Lactams; Lactams, Macrocyclic; Models, Biological; Osteosarcoma; Pyrazoles; Spheroids, Cellular; Tumor Microenvironment | 2020 |
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.
Topics: Aminopyridines; Animals; Carcinogenesis; Macrophage Colony-Stimulating Factor; Mice; Osteosarcoma; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2020 |
Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma.
Topics: Aminopyridines; Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytokines; Dogs; Female; Humans; Lung Neoplasms; Mice; Osteosarcoma; Phosphorylation; Rhabdomyosarcoma; Sarcoma, Ewing; STAT3 Transcription Factor; Sulfonamides; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
Therapeutic potential of nvp-bkm120 in human osteosarcomas cells.
Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Morpholines; Osteosarcoma; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction | 2019 |
Serum starvation-induced voltage-gated potassium channel Kv7.5 expression and its regulation by Sp1 in canine osteosarcoma cells.
Topics: Aminopyridines; Animals; Cell Line, Tumor; Cell Proliferation; Culture Media, Serum-Free; Dogs; KCNQ Potassium Channels; Osteosarcoma; Plicamycin; Sp1 Transcription Factor; Transcription, Genetic | 2014 |
Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells.
Topics: Aminopyridines; Antibodies, Monoclonal; Cell Line, Tumor; Cell Survival; Endothelin A Receptor Antagonists; Gangliosides; Humans; Morpholines; Neoplasm Invasiveness; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors | 2014 |
A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors.
Topics: Aminopyridines; Animals; Autophagy; Autophagy-Related Proteins; Catalytic Domain; Cell Line, Tumor; Computer Simulation; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; HEK293 Cells; Humans; Lipids; Mice; Mice, Nude; Neoplasm Transplantation; Osteosarcoma; Phosphatidylinositol 3-Kinases; TOR Serine-Threonine Kinases | 2014 |
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells.
Topics: Aminopyridines; Apoptosis; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplastic Stem Cells; Osteogenesis; Osteosarcoma; Pyrimidinones; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Structure-Activity Relationship | 2015 |
Evaluation of In Vitro Activity of the Class I PI3K Inhibitor Buparlisib (BKM120) in Pediatric Bone and Soft Tissue Sarcomas.
Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Class I Phosphatidylinositol 3-Kinases; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; Mechanistic Target of Rapamycin Complex 1; Morpholines; Multiprotein Complexes; Mutation; Osteosarcoma; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridones; Pyrimidines; Pyrimidinones; Pyrroles; Sarcoma; Signal Transduction; TOR Serine-Threonine Kinases | 2015 |