Page last updated: 2024-08-21

alpha-aminopyridine and Nervous System Disorders

alpha-aminopyridine has been researched along with Nervous System Disorders in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Busquet, N; Diaz, MJ; Gonzalez, MI; Lam, PM; Laoprasert, M; Raol, YH; Sampath, D; White, AM1
Ishibashi, K; Ishii, K; Kameyama, M; Miura, Y; Toyohara, J1
Cortese, F; De Giglio, L; Pennisi, EM1
Compter, A; de Waard, Q; Gafer, H; van den Heuvel, M1
Gavaldà, A; Lehner, MD; Pagès, L1
Althaus, M; Hanschmann, A; Klein, T; Magerl, W; Treede, RD1
Haley, TJ1
Lawson, K1
Bowe, CM; Veale, K1
Campbell, GA; Davis, KL; Haroutunian, V; Kanof, PD; Tsuboyama, GK1

Reviews

3 review(s) available for alpha-aminopyridine and Nervous System Disorders

ArticleYear
PDE4 inhibitors: a review of current developments (2005 - 2009).
    Expert opinion on therapeutic patents, 2009, Volume: 19, Issue:11

    Topics: Aminopyridines; Animals; Benzamides; Clinical Trials as Topic; Cyclopropanes; Drug Design; Humans; Inflammation; Nervous System Diseases; Patents as Topic; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors

2009
Physical and biological properties of pyrilamine.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:1

    Topics: Aminopyridines; Animals; Carcinogens; Chemical Phenomena; Chemistry; Chemistry, Physical; Humans; Immunity; Kinetics; Mutagens; Nervous System Diseases; Pyrilamine; Structure-Activity Relationship; Teratogens; Time Factors

1983
Is there a role for potassium channel openers in neuronal ion channel disorders?
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:10

    Topics: Aminopyridines; Animals; Anticonvulsants; Antihypertensive Agents; Ataxia; Carbamates; Diazoxide; Epilepsy; Humans; Ion Channels; Isaacs Syndrome; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mutation; Nervous System Diseases; Neuroprotective Agents; Parkinson Disease; Phenylenediamines; Potassium Channels

2000

Trials

1 trial(s) available for alpha-aminopyridine and Nervous System Disorders

ArticleYear
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia.
    European journal of pain (London, England), 2008, Volume: 12, Issue:1

    Topics: Aminopyridines; Analgesics; Capsaicin; Cross-Over Studies; Cyclopentanes; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; Nervous System Diseases; Pain; Physical Stimulation; Receptors, N-Methyl-D-Aspartate; Treatment Outcome

2008

Other Studies

6 other study(ies) available for alpha-aminopyridine and Nervous System Disorders

ArticleYear
Effects of a potassium channel opener on brain injury and neurologic outcomes in an animal model of neonatal hypoxic-ischemic injury.
    Pediatric research, 2020, Volume: 88, Issue:2

    Topics: Aminopyridines; Animals; Animals, Newborn; Anticonvulsants; Brain; Brain Injuries; Carotid Arteries; Cognition; Disease Models, Animal; Hand Strength; Hypoxia; Hypoxia-Ischemia, Brain; Male; Maze Learning; Motor Skills; Nervous System Diseases; Neuroprotection; Neuroprotective Agents; Potassium Channels; Quality of Life; Rats; Seizures

2020
Head-to-Head Comparison of the Two MAO-B Radioligands, 18F-THK5351 and 11C-L-Deprenyl, to Visualize Astrogliosis in Patients With Neurological Disorders.
    Clinical nuclear medicine, 2021, Volume: 46, Issue:1

    Topics: Aminopyridines; Carbon Radioisotopes; Female; Gliosis; Humans; Ligands; Male; Monoamine Oxidase; Nervous System Diseases; Positron-Emission Tomography; Quinolines; Selegiline

2021
Aminopiridines in the treatment of multiple sclerosis and other neurological disorders.
    Neurodegenerative disease management, 2020, Volume: 10, Issue:6

    Topics: 4-Aminopyridine; Aminopyridines; Humans; Lambert-Eaton Myasthenic Syndrome; Multiple Sclerosis; Nervous System Diseases; Potassium Channel Blockers; Quality of Life

2020
Rapid regression of neurological symptoms in patients with metastasised ALK+ lung cancer who are treated with lorlatinib: a report of two cases.
    BMJ case reports, 2019, Jul-24, Volume: 12, Issue:7

    Topics: Aminopyridines; Anaplastic Lymphoma Kinase; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Crizotinib; Female; Humans; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Diseases; Progression-Free Survival; Pyrazoles; Remission Induction; Treatment Outcome

2019
Sensitivity to 4-aminopyridine observed in mammalian sciatic nerves during acute pyridoxine-induced sensory neuropathy and recovery.
    Experimental neurology, 1988, Volume: 100, Issue:3

    Topics: 4-Aminopyridine; Action Potentials; Acute Disease; Aminopyridines; Animals; Female; Nerve Fibers, Myelinated; Nervous System Diseases; Pyridoxine; Rats; Rats, Inbred Strains; Reaction Time; Sciatic Nerve; Sensation; Spinal Nerve Roots

1988
Animal models of Alzheimer's disease: behavior, pharmacology, transplants.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1986, Volume: 13, Issue:4 Suppl

    Topics: 4-Aminopyridine; Alzheimer Disease; Aminopyridines; Animals; Behavior, Animal; Brain; Disease Models, Animal; Fetus; Growth Substances; Humans; Nerve Growth Factors; Nerve Tissue; Nerve Tissue Proteins; Nervous System Diseases; Norepinephrine; Parasympathetic Nervous System; Physostigmine; Somatostatin

1986