Page last updated: 2024-08-21

alpha-aminopyridine and Nerve Pain

alpha-aminopyridine has been researched along with Nerve Pain in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Bao, Y; Chen, Y; Huang, C; Qin, H; Xiao, X; Zhang, G; Zhou, H; Zhu, J; Zhuang, T1
Liu, ZX; Zhang, WJ; Zhu, ZM1
Maruyama, M; Miyake, K; Miyake, N; Okada, T; Saitow, F; Sakai, A; Shimada, T; Suzuki, H1
Fleck, SC; Geisslinger, G; Möller, M; Möser, CV; Niederberger, E; Thomas, D1
Cooke, I; Goodchild, CS; Kolosov, A; Tucker, AP1
Ashby, M; Cooke, I; Goodchild, CS; Jackson, K; Nelson, J1
Arrowsmith, J; Drummond, KS; Feltner, DE; Morgan, P; Street, SD; Van Der Graaf, PH; Wegner, CD1
Szelenyi, I1

Reviews

2 review(s) available for alpha-aminopyridine and Nerve Pain

ArticleYear
The role of P2X4 receptor in neuropathic pain and its pharmacological properties.
    Pharmacological research, 2020, Volume: 158

    Topics: Aminopyridines; Animals; Humans; Microglia; Neuralgia; Oxazines; Phenylurea Compounds; Protein Structure, Secondary; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X4

2020
Flupirtine, a re-discovered drug, revisited.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:3

    Topics: Aminopyridines; Analgesics; Epilepsy; Humans; KCNQ Potassium Channels; Neuralgia; Neuromuscular Agents; Urinary Bladder, Overactive

2013

Trials

1 trial(s) available for alpha-aminopyridine and Nerve Pain

ArticleYear
Combination therapy with flupirtine and opioid: open-label case series in the treatment of neuropathic pain associated with cancer.
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Middle Aged; Morphine; Neuralgia; Pain Measurement; Palliative Care; Treatment Outcome

2008

Other Studies

5 other study(ies) available for alpha-aminopyridine and Nerve Pain

ArticleYear
Flupirtine and antihistamines exert synergistic anti-nociceptive effects in mice.
    Psychopharmacology, 2023, Volume: 240, Issue:4

    Topics: Aminopyridines; Analgesics; Animals; Carrageenan; Histamine Antagonists; Mice; Neuralgia; Promethazine

2023
MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain.
    Nature communications, 2017, 07-05, Volume: 8

    Topics: Aminopyridines; Animals; Chronic Pain; Down-Regulation; Ganglia, Spinal; Hyperalgesia; Male; MicroRNAs; Neuralgia; Neurons; Phenylurea Compounds; Potassium Channels, Voltage-Gated; Rats, Sprague-Dawley; Tetrazoles

2017
Inhibition of the protein kinase IKKepsilon attenuates neuropathic pain in mice.
    Neuropharmacology, 2019, 03-01, Volume: 146

    Topics: Aminopyridines; Animals; Disease Models, Animal; Female; Ganglia, Spinal; Hyperalgesia; I-kappa B Kinase; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Neuralgia; NF-kappa B; Peripheral Nerve Injuries; Protein Serine-Threonine Kinases; Sciatic Nerve; Signal Transduction; Spinal Cord

2019
Combination therapy with flupirtine and opioid: studies in rat pain models.
    Pain medicine (Malden, Mass.), 2008, Volume: 9, Issue:7

    Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Male; Morphine; Neuralgia; Pain Measurement; Rats; Rats, Wistar; Treatment Outcome

2008
Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival.
    Drug discovery today, 2012, Volume: 17, Issue:9-10

    Topics: Aminopyridines; Animals; CCR5 Receptor Antagonists; Clinical Trials, Phase II as Topic; Cyclohexanes; Drug Evaluation; HIV Infections; Humans; Maraviroc; Morpholines; Neuralgia; Pharmaceutical Preparations; Pharmacokinetics; Receptors, Dopamine D3; Sexual Dysfunction, Physiological; Triazoles

2012