Page last updated: 2024-08-21

alpha-aminopyridine and Liver Dysfunction

alpha-aminopyridine has been researched along with Liver Dysfunction in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Greenberg, J; Healey, JH; Hsu, C; LaCreta, F; Lasseter, KC; Marbury, TC; Stacchiotti, S; Tap, WD; Xu, LA; Zahir, H1
Ji, Y; Miller, M; Samant, TS; Yang, S1
Chen, J; Cheng, Y; Feng, H; Wang, H; Xu, J; Zhong, Q; Zou, Z1
Houwen, RHJ; Slae, M; van der Woerd, WL; Wilschanski, M1
Bertolini, A; Bodewes, FAJA; Jonker, JW; van de Peppel, IP; Verkade, HJ1
Csonka, D; Duval, V; Hazell, K; Kobalava, ZD; Lorenzo, S; Trandafir, L; Waldron, E1
Gillen, M; Marbury, T; Martin, P; Millson, D; Oliver, S1
Anderson, N; Borlak, J1
Miller, RD1
Powell-Jackson, P; Williams, R1
Dent, JG; Graichen, ME; Leonard, TB; Neptun, DA; Popp, JA1

Reviews

3 review(s) available for alpha-aminopyridine and Liver Dysfunction

ArticleYear
Effects of new and emerging therapies on gastrointestinal outcomes in cystic fibrosis.
    Current opinion in pulmonary medicine, 2017, Volume: 23, Issue:6

    Topics: Aminophenols; Aminopyridines; Benzodioxoles; Body Mass Index; Chloride Channel Agonists; Cystic Fibrosis; Digestive System; Drug Combinations; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Intestinal Diseases; Liver Diseases; Probiotics; Quinolones; Treatment Outcome; Weight Gain

2017
Diagnosis, follow-up and treatment of cystic fibrosis-related liver disease.
    Current opinion in pulmonary medicine, 2017, Volume: 23, Issue:6

    Topics: Aftercare; Aminophenols; Aminopyridines; Benzodioxoles; Chloride Channel Agonists; Cholagogues and Choleretics; Cystic Fibrosis; Drug Combinations; Elasticity Imaging Techniques; Humans; Liver Diseases; Liver Transplantation; Quinolones; Ursodeoxycholic Acid

2017
Recent developments with muscles relaxants and their antagonists.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:2

    Topics: Acidosis; Aminopyridines; Electric Stimulation; Humans; Hypothermia; Kidney Diseases; Liver Diseases; Neostigmine; Neuromuscular Blocking Agents; Neuromuscular Junction; Pancuronium; Peripheral Nerves; Respiration; Sensory Receptor Cells; Synaptic Transmission; Water-Electrolyte Balance

1979

Trials

3 trial(s) available for alpha-aminopyridine and Liver Dysfunction

ArticleYear
Pharmacokinetics of Ribociclib in Subjects With Hepatic Impairment.
    Journal of clinical pharmacology, 2021, Volume: 61, Issue:8

    Topics: Aminopyridines; Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Female; Half-Life; Humans; Liver Diseases; Male; Metabolic Clearance Rate; Middle Aged; Patient Acuity; Purines

2021
A phase-1, open-label, single-dose study of the pharmacokinetics of buparlisib in subjects with mild to severe hepatic impairment.
    Journal of clinical pharmacology, 2016, Volume: 56, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aminopyridines; Antineoplastic Agents; Case-Control Studies; Female; Humans; Liver Diseases; Male; Middle Aged; Morpholines; Severity of Illness Index; Young Adult

2016
Pharmacokinetic Properties of Fostamatinib in Patients With Renal or Hepatic Impairment: Results From 2 Phase I Clinical Studies.
    Clinical therapeutics, 2015, Dec-01, Volume: 37, Issue:12

    Topics: Aminopyridines; Arthritis, Rheumatoid; Female; Humans; Kidney Diseases; Liver Diseases; Male; Middle Aged; Morpholines; Oxazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines

2015

Other Studies

5 other study(ies) available for alpha-aminopyridine and Liver Dysfunction

ArticleYear
Effect of Mild and Moderate Hepatic Impairment (Defined by Child-Pugh Classification and National Cancer Institute Organ Dysfunction Working Group Criteria) on Pexidartinib Pharmacokinetics.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:8

    Topics: Aminopyridines; Area Under Curve; Humans; Liver Diseases; Multiple Organ Failure; National Cancer Institute (U.S.); Neoplasms; Pyrroles; United States

2022
Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice.
    Laboratory investigation; a journal of technical methods and pathology, 2017, Volume: 97, Issue:9

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Bacterial Load; Benzamides; Cyclopropanes; Cytokines; Inflammation; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Sepsis; STAT3 Transcription Factor; Survival Analysis

2017
Correlation versus causation? Pharmacovigilance of the analgesic flupirtine exemplifies the need for refined spontaneous ADR reporting.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aminopyridines; Analgesics; Bile Duct Diseases; Causality; Chemical and Drug Induced Liver Injury; Female; Germany; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Pharmacovigilance; Virus Diseases; World Health Organization

2011
Use of flupirtine maleate as an analgesic in patients with liver disease.
    The British journal of clinical practice, 1985, Volume: 39, Issue:2

    Topics: Adult; Aged; Aminopyridines; Analgesics; Female; Humans; Liver Diseases; Male; Middle Aged; Palliative Care

1985
Effects of methapyrilene on rat hepatic xenobiotic metabolizing enzymes and liver morphology.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:1

    Topics: Alanine Transaminase; Aminopyridines; Animals; Bile Acids and Salts; Bile Ducts; Chemical and Drug Induced Liver Injury; Epoxide Hydrolases; gamma-Glutamyltransferase; Liver Diseases; Liver Function Tests; Male; Methapyrilene; Microsomes, Liver; Mixed Function Oxygenases; Necrosis; Rats; Rats, Inbred F344

1985