alpha-aminopyridine has been researched along with Insulin Resistance in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Arner, EN; Brekken, RA; Cruz, VH; Scherer, PE; Wynne, KW | 1 |
| Adams, SE; Brooks, AES; Jaiswal, JK; Jamieson, SMF; Masson, SW; Merry, TL; Shepherd, PR | 1 |
| Calay, ES; Hotamisligil, GS | 1 |
| Anthony, J; Bhumra, SK; Deka, N; Kelkar, A; Marita, AR; Mutt, S; Mutt, SJ; Ranjith, V; Sharma, S; Sivaramakrishnan, H; Wilankar, C | 1 |
| Gao, R; Guo, T; Hu, X; Li, J; Liu, Z; Mei, H; Ming, Y; Song, Y; Wang, B; Wu, C; Xiao, L; Xiao, X; Zhang, Y | 1 |
| Ahmadian, M; Chang, L; Downes, M; Evans, RM; Korytnaya, E; Krause, DM; Liddle, C; Lumeng, CN; Neidert, A; Oral, EA; Peng, X; Poirier, B; Reilly, SM; Saltiel, AR; Uhm, M; Yu, RT; Zamarron, BF | 1 |
| Choi, SH; Durrance, ES; Jang, HC; Jin, H; Kim, KM; Kim, YB; Lee, GY; Lee, KS; Lim, S; Park, HS; Park, KS | 1 |
| Chen, H; Chen, Z; Dong, H; Huang, C; Li, G; Li, X; Luo, D; Sun, L; Sun, S; Wei, S; Yang, H; Zhou, Y | 1 |
| Albrecht-Küpper, B; Dinh, W; Gheorghiade, M; Sabbah, HN; van der Laan, M; Voors, AA | 1 |
| Baeck, C; Federici, M; Kahles, F; Kappel, B; Lebherz, C; Lehrke, M; Marx, N; Möllmann, J; Tacke, F; Werner, C | 1 |
| Black, SC; Briscoe, CP; Chen, P; Cho, H; Fraser, J; Kelly-Sullivan, D; Looper, D; McDonnell, SR; Ogilvie, KM; Shi, M; Siegel, K; Timofeevski, S; Yie, J; Yu, XH | 1 |
| Chang, L; Chiang, SH; Decker, SJ; Downes, M; Evans, RM; Hochberg, I; Larsen, MJ; Li, P; Liddle, C; Mowers, J; Oh, D; Olefsky, JM; Reilly, SM; Rubin, JR; Saltiel, AR; Uhm, M; White, NM; Yu, RT | 1 |
| Goff, D; Hammond, ME; Harrison, SD; Henriksen, EJ; Johnson, KW; Kinnick, TR; Ma, ST; Nuss, JM; Reeder, JW; Ring, DB; Samuels, I; Slabiak, T; Wagman, AS | 1 |
1 review(s) available for alpha-aminopyridine and Insulin Resistance
| Article | Year |
|---|---|
Partial Adenosine A1 Agonist in Heart Failure.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Aminopyridines; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Coronary Artery Disease; Diabetes Mellitus; Dipeptides; Drug Partial Agonism; Furans; Heart; Heart Failure; Humans; Insulin Resistance; Ischemic Preconditioning, Myocardial; Lipolysis; Mitochondria, Heart; Myocardium; Oxygen Consumption; Pyridines; Renal Insufficiency; Tachycardia, Supraventricular; Thiazoles | 2017 |
1 trial(s) available for alpha-aminopyridine and Insulin Resistance
| Article | Year |
|---|---|
A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.
Topics: 3T3-L1 Cells; Adipocytes; Adult; Aged; Aminopyridines; Animals; Cyclic AMP; Female; Gene Knockdown Techniques; Gluconeogenesis; Glucose-6-Phosphatase; Humans; Inflammation; Insulin Resistance; Interleukin-6; Liver; Male; Mice; Mice, Inbred C57BL; Middle Aged; p38 Mitogen-Activated Protein Kinases; Receptors, Adrenergic, beta; Signal Transduction; STAT3 Transcription Factor; Subcutaneous Fat; Young Adult | 2015 |
12 other study(ies) available for alpha-aminopyridine and Insulin Resistance
| Article | Year |
|---|---|
Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.
Topics: Aminopyridines; Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Fatty Liver; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Weight Loss | 2018 |
The CSF1 receptor inhibitor pexidartinib (PLX3397) reduces tissue macrophage levels without affecting glucose homeostasis in mice.
Topics: Adipose Tissue; Aminopyridines; Animals; Diet, High-Fat; Glucose; Homeostasis; Insulin Resistance; Macrophages; Mice; Obesity; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2020 |
Turning off the inflammatory, but not the metabolic, flames.
Topics: Aminopyridines; Animals; Anti-Obesity Agents; Energy Metabolism; I-kappa B Kinase; Insulin Resistance; Male; Obesity; Protein Serine-Threonine Kinases | 2013 |
Discovery of p1736, a novel antidiabetic compound that improves peripheral insulin sensitivity in mice models.
Topics: Adipocytes; Aminopyridines; Animals; Diabetes Mellitus, Type 2; Drug Discovery; Glucose; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistance; Metformin; Mice; Mice, Mutant Strains; Rosiglitazone; Sulfonamides; Thiazolidinediones | 2013 |
CMHX008, a novel peroxisome proliferator-activated receptor γ partial agonist, enhances insulin sensitivity in vitro and in vivo.
Topics: 3T3-L1 Cells; Adipose Tissue, White; Aminopyridines; Animals; Anti-Inflammatory Agents; Cell Differentiation; Cell Polarity; Diet, High-Fat; Drug Evaluation, Preclinical; Dyslipidemias; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; PPAR gamma; Rosiglitazone; Thiazolidinediones; Transcriptional Activation | 2014 |
Anti-diabetic efficacy of KICG1338, a novel glycogen synthase kinase-3β inhibitor, and its molecular characterization in animal models of type 2 diabetes and insulin resistance.
Topics: Aminopyridines; Animals; Carboxylic Acids; Diabetes Mellitus, Type 2; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Expression Regulation; Glucose; Glucose Tolerance Test; Glycogen Synthase Kinase 3; Hypoglycemic Agents; Imidazoles; Insulin Resistance; Mice; Mice, Obese; Rats; Rats, Inbred OLETF; Receptors, Leptin | 2015 |
Arg⁹⁷² insulin receptor substrate-1 inhibits endothelial nitric oxide synthase expression in human endothelial cells by upregulating microRNA-155.
Topics: Adult; Aged; Aminopyridines; Cells, Cultured; Diabetes Mellitus; Enzyme Activation; Female; Human Umbilical Vein Endothelial Cells; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; MicroRNAs; Middle Aged; Morpholines; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Transfection | 2015 |
The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism.
Topics: Aminopyridines; Animals; Benzamides; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Diet, High-Fat; Energy Metabolism; Glucose; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Signal Transduction; Weight Gain | 2017 |
Pharmacological characterization of a small molecule inhibitor of c-Jun kinase.
Topics: 3T3-L1 Cells; Adipose Tissue, White; Aminopyridines; Animals; Blood Glucose; Body Weight; Cytokines; Dietary Fats; Eating; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; Obesity; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Tumor Necrosis Factor-alpha; U937 Cells | 2008 |
[COPD and diabetes mellitus. Does pulmonary medication modify blood glucose metabolism?].
Topics: Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Blood Glucose; Cholinergic Antagonists; Cyclopropanes; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypoglycemic Agents; Insulin Resistance; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive | 2011 |
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.
Topics: Aminopyridines; Animals; Anti-Allergic Agents; Anti-Obesity Agents; Cell Line; Diet, High-Fat; Energy Metabolism; Enzyme Activation; Fatty Liver; Glucose Metabolism Disorders; I-kappa B Kinase; Insulin Resistance; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Obesity; Oxygen Consumption; Protein Serine-Threonine Kinases; Weight Loss | 2013 |
Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo.
Topics: Aminopyridines; Animals; Biological Transport; CHO Cells; Cricetinae; Diabetes Mellitus; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression; Glucose; Glycogen Synthase; Glycogen Synthase Kinase 3; Hepatocytes; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptor, Insulin; Transfection | 2003 |