Page last updated: 2024-08-21

alpha-aminopyridine and Graft vs Host Disease

alpha-aminopyridine has been researched along with Graft vs Host Disease in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Alyea, EP; Anand, SM; Bracken, SJ; Cardones, AR; Chao, NJ; Choi, T; DiCioccio, RA; Gasparetto, C; Grunwald, MR; Haykal, T; Hennig, T; Horwitz, ME; Jia, W; Kang, Y; Li, Z; Lin, C; Long, GD; Lopez, R; Martin, M; McManigle, WC; Minor, KK; Poe, JC; Quinones, VLP; Rizzieri, DA; Sarantopoulos, S; Sung, AD; Wiggins, K1
Fang, JP; Han, XW; Huang, K; Li, XY; Xu, LH; Zhang, YT1
Date, M; Fujimoto, M; Hamaguchi, Y; Hasegawa, M; Hau, KT; Kimura, H; Le Huu, D; Matsushita, T; Takehara, K1
Alexander, KA; Allen, JL; Antin, JH; Blazar, BR; Chao, NJ; Clynes, RA; Cutler, CS; Du, J; Flynn, R; Hill, GR; Koreth, J; Luznik, L; MacDonald, KP; Maillard, I; Murphy, WJ; Panoskaltsis-Mortari, A; Paz, K; Poe, JC; Ritz, J; Sarantopoulos, S; Serody, JS; Soiffer, RJ; Taylor, PA; Vulic, A1
Cho, CS; Kim, JH; Kim, SW; Kim, TJ; Lim, JY; Min, CK; Park, CK; Rhee, CK; Yoon, HK1
Almeida, J; Blanco, B; Corchete, LA; Del Cañizo, C; García-Briñón, J; Herrero-Sánchez, MC; Inogés, S; Rodríguez-Serrano, C; San Miguel, JF; San Segundo, L; Santos-Briz, Á1
Althage, A; Beyer, C; Chen, CW; Cole, SH; Distler, JH; Gergely, P; Harris, JL; Hsieh, MH; Li, C; Liu, J; Maier, C; Meeusen, S; Ng, N; Pan, S; Schett, G; Seidel, HM; Svensson, EC; Trinh-Minh, T; Xu, X1
Buchner, M; Fisch, P; Gerlach, UV; Hechinger, AK; Leonhardt, F; Prinz, G; Reichardt, W; Schmitt-Gräff, A; Zeiser, R; Zirlik, K1

Trials

1 trial(s) available for alpha-aminopyridine and Graft vs Host Disease

ArticleYear
A Phase I Trial of SYK Inhibition with Fostamatinib in the Prevention and Treatment of Chronic Graft-Versus-Host Disease.
    Transplantation and cellular therapy, 2023, Volume: 29, Issue:3

    Topics: Aminopyridines; Animals; Bronchiolitis Obliterans Syndrome; Graft vs Host Disease; Humans; Mice; Neoplasm Recurrence, Local; Oxazines; Pyridines; Steroids; Syk Kinase

2023

Other Studies

7 other study(ies) available for alpha-aminopyridine and Graft vs Host Disease

ArticleYear
[Preliminary Study of Chidamide Combined with Hematopoietic Stem Cell Transplantation in the Treatment of Childhood Acute T-Lymphoblastic Leukemia].
    Zhongguo shi yan xue ye xue za zhi, 2020, Volume: 28, Issue:3

    Topics: Aminopyridines; Benzamides; Child; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Transplantation, Homologous

2020
Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease.
    Journal of dermatological science, 2014, Volume: 74, Issue:3

    Topics: Aminopyridines; Animals; B-Lymphocytes; Bone Marrow Transplantation; Chemokines; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Graft vs Host Disease; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred BALB C; Monocytes; Morpholines; Oxazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Receptors, CXCR4; Scleroderma, Systemic; Syk Kinase; T-Lymphocytes

2014
Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.
    Blood, 2015, Jun-25, Volume: 125, Issue:26

    Topics: Aminopyridines; Animals; B-Lymphocytes; Disease Models, Animal; Enzyme Inhibitors; Female; Flow Cytometry; Fluorescent Antibody Technique; Graft vs Host Disease; Humans; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Morpholines; Oxazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Syk Kinase

2015
Effect of roflumilast, novel phosphodiesterase-4 inhibitor, on lung chronic graft-versus-host disease in mice.
    Experimental hematology, 2016, Volume: 44, Issue:5

    Topics: Aminopyridines; Animals; Benzamides; Blotting, Western; Bone Marrow Transplantation; Cell Transplantation; Chemokine CCL2; Chemokine CCL3; Cyclopropanes; Female; Gene Expression; Graft vs Host Disease; Interleukin-1beta; Interleukin-6; Lung; Lymphocyte Count; Mice, Inbred BALB C; Phosphodiesterase 4 Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Spleen; T-Lymphocytes, Regulatory; Transforming Growth Factor beta1; Transplantation, Homologous

2016
Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development.
    Journal of hematology & oncology, 2016, 10-20, Volume: 9, Issue:1

    Topics: Aminopyridines; Animals; Cell Proliferation; Graft vs Host Disease; Imidazoles; Lymphocyte Activation; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Signal Transduction; T-Lymphocytes; TOR Serine-Threonine Kinases

2016
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:4

    Topics: Acyltransferases; Aminopyridines; Animals; Bleomycin; Disease Models, Animal; Disease Progression; Female; Fibrosis; Graft vs Host Disease; Membrane Proteins; Mice, Inbred BALB C; Piperazines; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Scleroderma, Localized; Scleroderma, Systemic; Skin; Transforming Growth Factor beta; Wnt Signaling Pathway

2017
Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels.
    Leukemia, 2012, Volume: 26, Issue:7

    Topics: Aminopyridines; Animals; Antigen-Presenting Cells; Blotting, Western; Bone Marrow Transplantation; Cell Movement; Cell Proliferation; Cytomegalovirus; Cytomegalovirus Infections; Dendritic Cells; Female; Flow Cytometry; Graft vs Host Disease; Graft vs Leukemia Effect; Intracellular Signaling Peptides and Proteins; Leukemia; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morpholines; Oxazines; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Spleen; Syk Kinase; T-Lymphocytes; Transplantation, Homologous

2012