Compounds > alpha-aminopyridine
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alpha-aminopyridine and Glioma

alpha-aminopyridine has been researched along with Glioma in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Guo, Z; Han, L; Li, Z; Wang, H; Wei, J; Zhou, H1
Cao, Y; Kong, S; Li, X; Qi, Y; Shang, S1
Jung, SY; Lee, JH; Yoo, K; Yun, HH1
Bagchi, A; Boop, F; Campagne, O; Christensen, AM; Dhanda, S; Furtado, LV; Gajjar, A; Nair, S; Orr, BA; Robinson, GW; Stewart, C; Tran, Q; Vasilyeva, A1
Amiri, H; Caenepeel, S; Coxon, A; de Bitter, T; Dussault, I; Heerschap, A; Hendriks, W; Leenders, WPJ; Navis, AC; Rex, K; Span, PN; van den Heuvel, CNAM; Verrijp, K; Wesseling, P1
Akkari, L; Huse, JT; Joyce, JA; Kowal, J; Schuhmacher, AJ; West, BL; Yan, D1
Affolter, T; Appleman, V; Brooun, A; Charest, A; Deng, YL; Engstrom, LD; Falk, MD; Fantin, VR; Hu, W; Jiang, P; Johnson, TW; Lam, J; Lappin, PB; Li, Q; Liu, W; McDonnell, SR; McTigue, M; Nichols, T; Smeal, T; Timofeevski, S; West, M; Wong, KA; Zou, HY1
Foster, KA; Jane, EP; Morales, A; Pollack, IF; Premkumar, DR1
Chong, Y; Gao, S; Liu, H; Liu, N; Liu, X; Niu, M; Qi, Z; Tu, Y; Yao, Y; Yu, R; Yue, C1
Färber, K; Kettenmann, H; Stragies, R; Synowitz, M; van Rooijen, N; Vossmeyer, D; Zahn, G1
Fu, J; Garcia-Echevrria, C; Kim, YW; Koul, D; LaFortune, TA; Liu, JL; Maira, SM; Ramnarian, D; Shen, R; Tiao, N; Wang, S; Yuan, Y; Yung, WK1
Brismar, T; Collins, VP2

Other Studies

13 other study(ies) available for alpha-aminopyridine and Glioma

ArticleYear
Chidamide Inhibits Glioma Cells by Increasing Oxidative Stress via the miRNA-338-5p Regulation of Hedgehog Signaling.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Aminopyridines; Benzamides; Brain Neoplasms; Cell Movement; Glioma; Hedgehog Proteins; Histone Deacetylases; Humans; MicroRNAs; Neoplasm Invasiveness; Signal Transduction; Transfection

2020
CDK4/6 inhibition suppresses tumour growth and enhances the effect of temozolomide in glioma cells.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:9

    Topics: Aminopyridines; Animals; Apoptosis; Benzimidazoles; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; Retinoblastoma Protein; Spheroids, Cellular; Temozolomide; Up-Regulation; Xenograft Model Antitumor Assays

2020
KRIBB11 Induces Apoptosis in A172 Glioblastoma Cells via MULE-Dependent Degradation of MCL-1.
    Molecules (Basel, Switzerland), 2021, Jul-08, Volume: 26, Issue:14

    Topics: Aminopyridines; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Indazoles; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases

2021
Lorlatinib in a Child with
    The New England journal of medicine, 2021, 08-19, Volume: 385, Issue:8

    Topics: Aminopyridines; Anaplastic Lymphoma Kinase; Brain Neoplasms; Child, Preschool; Combined Modality Therapy; Glioma; Humans; Lactams; Lactams, Macrocyclic; Magnetic Resonance Imaging; Neoplasm Recurrence, Local; Pyrazoles; Remission Induction

2021
Selective MET Kinase Inhibition in MET-Dependent Glioma Models Alters Gene Expression and Induces Tumor Plasticity.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:11

    Topics: Aminopyridines; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; HT29 Cells; Humans; Mice; Protein Kinase Inhibitors; Pyrazoles; Sequence Analysis, RNA; Small Molecule Libraries; Xenograft Model Antitumor Assays

2017
Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.
    Oncogene, 2017, 10-26, Volume: 36, Issue:43

    Topics: Aminopyridines; Animals; Becaplermin; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Glioma; Humans; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Tumor Microenvironment

2017
PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Mar-17, Volume: 112, Issue:11

    Topics: Aminopyridines; Animals; Carcinogenesis; Cell Proliferation; Crizotinib; Crystallography, X-Ray; Disease Models, Animal; Drug Resistance, Neoplasm; Glioma; Humans; Lactams; Lactams, Macrocyclic; Mice; Models, Molecular; Mutation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrazoles; Pyridines; Signal Transduction

2015
NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5.
    International journal of oncology, 2015, Volume: 47, Issue:2

    Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Glioma; Humans; Morpholines; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation

2015
CRM1/XPO1 is associated with clinical outcome in glioma and represents a therapeutic target by perturbing multiple core pathways.
    Journal of hematology & oncology, 2016, 10-12, Volume: 9, Issue:1

    Topics: Aminopyridines; Animals; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Cyclopentanes; Exportin 1 Protein; Glioma; GTP-Binding Proteins; Heterografts; Humans; Intracellular Signaling Peptides and Proteins; Karyopherins; Mice; Prognosis; Receptors, Cytoplasmic and Nuclear; Retinoblastoma Binding Proteins; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2016
An alpha5beta1 integrin inhibitor attenuates glioma growth.
    Molecular and cellular neurosciences, 2008, Volume: 39, Issue:4

    Topics: Aminopyridines; Animals; Cell Movement; Cells, Cultured; Cytokines; Glioma; Integrin alpha5beta1; Mice; Mice, Inbred C57BL; Microglia; Neoplasm Transplantation; Propionates; Tissue Culture Techniques

2008
Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jan-01, Volume: 18, Issue:1

    Topics: Aminopyridines; Animals; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Proliferation; Enzyme Inhibitors; Fluorescent Antibody Technique; Glioma; Humans; Immunoenzyme Techniques; Mice; Mice, Nude; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2012
Inward rectifying potassium channels in human malignant glioma cells.
    Brain research, 1989, Feb-20, Volume: 480, Issue:1-2

    Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Glioma; Humans; Ion Channels; Membrane Potentials; Potassium; Tetraethylammonium Compounds; Tumor Cells, Cultured

1989
Potassium and sodium channels in human malignant glioma cells.
    Brain research, 1989, Feb-20, Volume: 480, Issue:1-2

    Topics: 4-Aminopyridine; Aminopyridines; Calcium; Cell Line; Glioma; Humans; Ion Channels; Potassium; Sodium; Tetraethylammonium Compounds; Tumor Cells, Cultured

1989