alpha-aminopyridine has been researched along with Giant Cell Tumor of Tendon Sheath in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 18 (94.74) | 2.80 |
| Authors | Studies |
|---|---|
| French, J; Gelderblom, H; Greenberg, J; Healey, JH; Polhamus, D; Shuster, D; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, X; Yin, O; Zahir, H | 1 |
| Beckett, B; Hansford, B; Helming, A | 1 |
| Anthony, SP; Braiteh, F; Chmielowski, B; Cohn, AL; Cote, GM; Gelhorn, HL; Healey, JH; Hsu, HH; Keedy, VL; Lin, PS; Peterfy, C; Puzanov, I; Severson, P; Shapiro, GI; Sherman, E; Singh, AS; Sterba, M; Tap, WD; Tong-Starksen, S; Wagner, AJ; Wainberg, ZA; West, BL; Ye, X; Zhang, C | 1 |
| Choi, Y; Dharmani, C; Diggs, A; Jiang, J; Keedy, VL; McCabe, C; Salas, M; Wang, E | 1 |
| Alcindor, T; Desai, J; Ganjoo, K; Gelderblom, H; Gelhorn, HL; Healey, JH; Martín-Broto, J; Palmerini, E; Shuster, D; Speck, RM; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, Q; Ye, X | 2 |
| Damron, TA | 1 |
| McCabe, C; Polson, K; Wagner, AJ; Wright, H | 1 |
| Lamb, YN | 1 |
| Donati, DM; Longhi, A; Palmerini, E; Staals, EL | 1 |
| Benner, B; Carson, WE; Cherian, MA; Good, L; Kassem, M; Quiroga, D; Sardesai, S; Schultz, TE; Wesolowski, R | 1 |
| Baldi, GG; Gronchi, A; Stacchiotti, S | 1 |
| Lazaridis, D; Monestime, S | 1 |
| de Sande, MV; Gelderblom, H | 1 |
| Tap, W | 1 |
| Gelderblom, H; Healey, JH; Kang, J; Knebel, W; Shuster, D; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Yin, O; Zahir, H | 1 |
| Alsayadi, YMMA; Chawla, PA | 1 |
| Bernthal, NM; Desai, J; Frezza, AM; Gelderblom, H; Healey, JH; Hsu, HH; Palmerini, E; Peterfy, CG; Shuster, DE; Staals, EL; Stacchiotti, S; Tap, WD; van de Sande, MAJ; Wagner, AJ; Wainberg, ZA; Wang, Q | 1 |
| Baba, HA; Bauer, S; Choi, Y; Druta, M; Gelderblom, H; Healey, JH; Lewis, JH; Lin, CC; Pousa, AL; Shuster, DE; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, Q | 1 |
8 review(s) available for alpha-aminopyridine and Giant Cell Tumor of Tendon Sheath
| Article | Year |
|---|---|
Turalio risk evaluation and mitigation strategy for treatment of tenosynovial giant cell tumor: framework and experience.
Topics: Adult; Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pyrroles; Risk Evaluation and Mitigation; United States; United States Food and Drug Administration | 2022 |
Pexidartinib: First Approval.
Topics: Aminopyridines; Antineoplastic Agents; Drug Approval; fms-Like Tyrosine Kinase 3; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Pyrroles; United States; United States Food and Drug Administration | 2019 |
Pexidartinib for the treatment of adult patients with symptomatic tenosynovial giant cell tumor: safety and efficacy.
Topics: Adult; Aminopyridines; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Neoplasm Recurrence, Local; Pyrroles; Quality of Life | 2020 |
Pexidartinib, a Novel Small Molecule CSF-1R Inhibitor in Use for Tenosynovial Giant Cell Tumor: A Systematic Review of Pre-Clinical and Clinical Development.
Topics: Aminopyridines; Antineoplastic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Giant Cell Tumor of Tendon Sheath; Humans; Molecular Structure; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Structure-Activity Relationship | 2020 |
Pexidartinib for the treatment of adult symptomatic patients with tenosynovial giant cell tumors.
Topics: Adult; Aminopyridines; Antineoplastic Agents; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Neoplasm Recurrence, Local; Pyrroles; Quality of Life; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor | 2020 |
Pexidartinib (TURALIO™): The First FDA-Indicated Systemic Treatment for Tenosynovial Giant Cell Tumor.
Topics: Administration, Oral; Adult; Aminopyridines; Antineoplastic Agents; Clinical Trials as Topic; Contraindications, Drug; Drug Approval; Drug Interactions; Female; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; United States; United States Food and Drug Administration | 2020 |
Pexidartinib: first approved systemic therapy for patients with tenosynovial giant cell tumor.
Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Diagnostic Imaging; Disease Management; Giant Cell Tumor of Tendon Sheath; Humans; Molecular Targeted Therapy; Neoplasm Staging; Protein Kinase Inhibitors; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Structure-Activity Relationship; Treatment Outcome | 2020 |
Prospects of Treating Tenosynovial Giant Cell Tumor through Pexidartinib: A Review.
Topics: Aminopyridines; Antineoplastic Agents; Giant Cell Tumor of Tendon Sheath; Humans; Macrophage Colony-Stimulating Factor; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; United States; United States Food and Drug Administration | 2021 |
3 trial(s) available for alpha-aminopyridine and Giant Cell Tumor of Tendon Sheath
| Article | Year |
|---|---|
Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
Topics: Adult; Aminopyridines; Double-Blind Method; Female; Giant Cell Tumor of Tendon Sheath; Humans; Middle Aged; Pain; Treatment Outcome | 2023 |
Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Agents; Area Under Curve; Asian People; Bacterial Proteins; Body Weight; Creatinine; Female; Giant Cell Tumor of Tendon Sheath; Humans; Kidney Function Tests; Liver Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Pyrroles; Racial Groups; Sex Factors; Sociodemographic Factors; Tumor Burden; Young Adult | 2021 |
Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial.
Topics: Adult; Aminopyridines; Double-Blind Method; Female; Giant Cell Tumor of Tendon Sheath; Humans; Lower Extremity; Male; Middle Aged; Patient Reported Outcome Measures; Pyrroles | 2021 |
8 other study(ies) available for alpha-aminopyridine and Giant Cell Tumor of Tendon Sheath
| Article | Year |
|---|---|
Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pyrroles; Response Evaluation Criteria in Solid Tumors | 2021 |
Tenosynovial giant cell tumor-diffuse type, treated with a novel colony-stimulating factor inhibitor, pexidartinib: initial experience with MRI findings in three patients.
Topics: Adult; Aminopyridines; Colony-Stimulating Factors; Giant Cell Tumor of Tendon Sheath; Humans; Magnetic Resonance Imaging; Pyrroles; Synovitis, Pigmented Villonodular | 2022 |
Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT.
Topics: Adult; Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Protein Kinase Inhibitors; Pyrroles | 2022 |
CORR Insights®: Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pain; Pyrroles | 2023 |
Supporting patients in the transition to the revised pexidartinib dosing regimen: perspectives from the multidisciplinary clinical and allied health professional team.
Topics: Adult; Allied Health Personnel; Aminopyridines; Chemical and Drug Induced Liver Injury; Giant Cell Tumor of Tendon Sheath; Humans; United States | 2023 |
ENLIVEN study: Pexidartinib for tenosynovial giant cell tumor (TGCT).
Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Protein Kinase Inhibitors; Pyrroles; Synovitis, Pigmented Villonodular | 2020 |
Long-term outcomes of pexidartinib in tenosynovial giant cell tumors.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Female; Giant Cell Tumor of Tendon Sheath; Humans; Male; Middle Aged; Pyrroles; Young Adult | 2021 |
Pexidartinib Long-Term Hepatic Safety Profile in Patients with Tenosynovial Giant Cell Tumors.
Topics: Aminopyridines; Chemical and Drug Induced Liver Injury; Giant Cell Tumor of Tendon Sheath; Humans; Liver; Pyrroles | 2021 |