Page last updated: 2024-08-21

alpha-aminopyridine and Electrocardiogram QT Prolonged

alpha-aminopyridine has been researched along with Electrocardiogram QT Prolonged in 8 studies

Research

Studies (8)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	6 (75.00)	24.3611
2020's	2 (25.00)	2.80

Authors

Authors	Studies
Ackerman, MJ; Hamrick, SK; John Kim, CS; O'Hare, BJ; Tester, DJ; Ye, D	1
Choudhury, P; Colecraft, HM; Jain, A; Kanner, SA; Shuja, Z	1
Chitre, A; Crotti, L; Gnecchi, M; Lua, CH; Mehta, A; Mura, M; Ramachandra, CJA; Schwartz, PJ; Shim, W; Singh, P; Wong, P	1
Delisle, BP; January, CT	1
Chi, W; Ferber, G; Jackson, J; Janku, F; Li, BT; Mendzelevski, B; Sager, PT; Sullivan, RJ; Welsch, D; Weng, O	1
Castelletti, S; Crotti, L; Dagradi, F; Gnecchi, M; Parati, G; Sala, L; Schwartz, PJ; Spazzolini, C	1
Chen, J; Crissey, A; Kulmatycki, K; Majumdar, T; Meyers, CD; Movva, A; Neelakantham, S; Noe, A; Salunke, A	1
Lopez-Garcia, JA; Rivera-Arconada, I; Vicente-Baz, J	1

Trials

2 trial(s) available for alpha-aminopyridine and Electrocardiogram QT Prolonged

Article	Year
Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies. Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:6 Topics: Aged; Aminopyridines; Dose-Response Relationship, Drug; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Protein Kinase Inhibitors; Pyrroles	2018
Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the QTcF Interval in Humans. Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6 Topics: Acetates; Adolescent; Adult; Aminopyridines; Body Mass Index; Diacylglycerol O-Acyltransferase; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Enzyme Inhibitors; Fluoroquinolones; Healthy Volunteers; Heart Rate; Humans; Hyperlipoproteinemia Type I; Long QT Syndrome; Male; Moxifloxacin; Young Adult	2016

Article

Year

Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies.

Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:6

Topics: Aged; Aminopyridines; Dose-Response Relationship, Drug; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Long QT Syndrome; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Protein Kinase Inhibitors; Pyrroles

2018

Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the QTcF Interval in Humans.

Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6

Topics: Acetates; Adolescent; Adult; Aminopyridines; Body Mass Index; Diacylglycerol O-Acyltransferase; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Enzyme Inhibitors; Fluoroquinolones; Healthy Volunteers; Heart Rate; Humans; Hyperlipoproteinemia Type I; Long QT Syndrome; Male; Moxifloxacin; Young Adult

2016

Other Studies

6 other study(ies) available for alpha-aminopyridine and Electrocardiogram QT Prolonged

Article	Year
Promise and Potential Peril With Lumacaftor for the Trafficking Defective Type 2 Long-QT Syndrome-Causative Variants, p.G604S, p.N633S, and p.R685P, Using Patient-Specific Re-Engineered Cardiomyocytes. Circulation. Genomic and precision medicine, 2020, Volume: 13, Issue:5 Topics: Action Potentials; Aminopyridines; Benzodioxoles; ERG1 Potassium Channel; Humans; Induced Pluripotent Stem Cells; Long QT Syndrome; Mutation, Missense; Myocytes, Cardiac; Phenotype; Polymorphism, Single Nucleotide; Protein Subunits	2020
Targeted deubiquitination rescues distinct trafficking-deficient ion channelopathies. Nature methods, 2020, Volume: 17, Issue:12 Topics: Aminophenols; Aminopyridines; Benzodioxoles; Channelopathies; Cystic Fibrosis; Deubiquitinating Enzymes; Drug Combinations; Humans; Indoles; Ion Transport; Long QT Syndrome; Myocytes, Cardiac; Nedd4 Ubiquitin Protein Ligases; Potassium Channels; Pyrazoles; Pyridines; Quinolines; Quinolones	2020
Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model. European heart journal, 2018, 04-21, Volume: 39, Issue:16 Topics: Action Potentials; Adolescent; Adult; Aminopyridines; Anti-Arrhythmia Agents; Benzodioxoles; Calcium; ERG1 Potassium Channel; Female; Humans; Induced Pluripotent Stem Cells; Long QT Syndrome; Male; Middle Aged; Myocytes, Cardiac; Protein Transport; Treatment Outcome	2018
Advancing precision medicine for the treatment of long-QT syndrome type 2: shedding light on lumacaftor. European heart journal, 2018, 04-21, Volume: 39, Issue:16 Topics: Aminopyridines; Benzodioxoles; Humans; Long QT Syndrome; Precision Medicine	2018
From patient-specific induced pluripotent stem cells to clinical translation in long QT syndrome Type 2. European heart journal, 2019, 06-14, Volume: 40, Issue:23 Topics: Adult; Aminophenols; Aminopyridines; Anti-Arrhythmia Agents; Benzodioxoles; Drug Combinations; Electrocardiography; Female; Humans; Induced Pluripotent Stem Cells; Long QT Syndrome; Precision Medicine; Quinolones	2019
Targeting Kv7 channels in pain pathways. Oncotarget, 2017, Feb-21, Volume: 8, Issue:8 Topics: Aminopyridines; Animals; Carbamates; Deafness; Epilepsy; Humans; Inflammation; KCNQ Potassium Channels; Long QT Syndrome; Mutation; Neurons; Pain; Pain Management; Phenylenediamines; Protein Conformation	2017