alpha-aminopyridine has been researched along with Diarrhea in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 9 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Anthony, S; Bajaj, A; Bhundia, V; Branson, A; Brookes, C; Darlison, L; Dawson, AG; Fennell, DA; Gaba, A; Greystoke, A; Hutka, M; King, A; Mohammed, S; Morgan, B; Nusrat, N; Poile, C; Richards, C; Scotland, M; Thomas, A; Wells-Jordan, P | 1 |
| Blancas, I; Boyle, F; Broom, R; Brown, J; Campone, M; Gumus, M; Hulstijn, M; Im, YH; Johnston, SRD; O'Shaughnessy, J; Rastogi, P; Reinisch, M; Rugo, HS; San Antonio, B; Shahir, A; Song, C; Toi, M; Tolaney, SM; Wei, R; Yamashita, T; Zagouri, F; Zimmermann, A | 1 |
| Boyle, F; Chapman, SC; Chen, Y; Ezquerra, MB; Gable, JC; Gainford, MC; Goksu, SS; Hossain, AM; Lim, E; Loi, S; Okera, M; Price, GL; van Hal, G | 1 |
| Bai, H; Zeng, S; Zou, M | 1 |
| Caruso, M; Gebbia, V; Giotta, F; Martorana, F; Piazza, D; Sanò, MV; Spada, M; Valerio, MR; Vigneri, P | 1 |
| Ansari, MN; Rehman, NU; Samad, A | 1 |
| Fortescue, R; Janjua, S; Poole, P | 1 |
| André, VAM; Chen, SC; Enatsu, S; Goetz, MP; Hae Park, I; Hardebeck, MC; Im, SA; Inoue, K; Iwata, H; Masuda, N; Sakaguchi, S; Sledge, GW; Sohn, J; Toi, M; Turner, PK | 1 |
| Abuhelwa, AY; Badaoui, S; Hopkins, AM; McKinnon, RA; Modi, ND; Rowland, A; Shankaran, K; Shaw, E; Sorich, MJ | 1 |
| Finkelstein, M; Franks, T; Hirakawa, B; Hu, W; Jessen, B; Kalabat, D; Khoh-Reiter, S; Lu, S; Sacaan, A; Sung, T; Thibault, S | 1 |
| Cai, Z; Enatsu, S; Ishiguro, H; Omori, Y | 1 |
| Horna, O; Toyas, C | 1 |
| Bolger, GB; Coricor, GE; Courville, CA; Dransfield, MT; Farris, RF; Lambert, JA; Li, Y; Mazur, MM; McNicholas, CM; Raju, SV; Rowe, SM; Smoot, LH; Tang, LP | 1 |
| Genovese, MC; Ho, M; Hollis, S; Kavanaugh, A; Leon, G; Millson, DS; Rosiak-Jedrychowicz, K; van der Heijde, D; Wang, M; Weinblatt, ME | 1 |
| Hussar, DA | 1 |
| Castellano, D; Chakravartty, A; Chi, KN; Csonka, D; de Bono, J; Dirix, L; Fizazi, K; Gravis, G; Machiels, JP; Maier, J; Massard, C; Mellado, B; Mita, A; Turri, S | 1 |
| Cripe, LD; De Vos, S; Friedberg, JW; Gregory, SA; Johnston, PB; Lacasce, A; Leonard, JP; Levy, R; Lowe, AM; Schaefer-Cutillo, J; Sharman, J; Shipp, MA; Sinha, R; Sterba, MP; Sweetenham, J; Vose, JM | 1 |
| Filatova, EG; Latysheva, NV; Naprienko, MV | 1 |
| Calero, C; Gutiérrez, C; López-Campos, JL | 1 |
| Bredenbröker, D; Brose, M; Calverley, PMA; Goehring, UM; Martinez, FJ; Rabe, KF; Wedzicha, JA | 1 |
| Boswell-Smith, V; Spina, D | 1 |
3 review(s) available for alpha-aminopyridine and Diarrhea
| Article | Year |
|---|---|
Effects of Roflumilast on Patients with Chronic Obstructive Pulmonary Disease Treated with Inhaled Corticosteroid/Long-Acting
Topics: Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Bronchodilator Agents; Cyclopropanes; Diarrhea; Disease Progression; Headache; Humans; Pulmonary Disease, Chronic Obstructive | 2022 |
Phosphodiesterase-4 inhibitors for chronic obstructive pulmonary disease.
Topics: Administration, Oral; Aminopyridines; Benzamides; Cyclohexanecarboxylic Acids; Cyclopropanes; Diarrhea; Disease Progression; Forced Expiratory Volume; Humans; Middle Aged; Nitriles; Peak Expiratory Flow Rate; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Quality of Life; Randomized Controlled Trials as Topic; Thiazoles; Vital Capacity | 2020 |
PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus on roflumilast.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Benzamides; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Diarrhea; Humans; Lung; Nausea; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Respiratory System Agents; Treatment Outcome; Vomiting | 2007 |
7 trial(s) available for alpha-aminopyridine and Diarrhea
| Article | Year |
|---|---|
Abemaciclib in patients with p16ink4A-deficient mesothelioma (MiST2): a single-arm, open-label, phase 2 trial.
Topics: Alanine Transaminase; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Diarrhea; Hemoptysis; Humans; Mesothelioma; Mesothelioma, Malignant; Pleural Neoplasms; Pulmonary Embolism; Respiratory Tract Infections; Sepsis; Thrombocytopenia; Vomiting | 2022 |
An open label, randomized phase 2 trial assessing the impact of food on the tolerability of abemaciclib in patients with advanced breast cancer.
Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Diarrhea; Female; Humans; Loperamide | 2022 |
Abemaciclib in combination with endocrine therapy for East Asian patients with HR+, HER2- advanced breast cancer: MONARCH 2 & 3 trials.
Topics: Aminopyridines; Anastrozole; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Fulvestrant; Humans; Letrozole; Neutropenia; Receptor, ErbB-2; Treatment Outcome | 2021 |
Effects of fostamatinib, an oral spleen tyrosine kinase inhibitor, in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminopyridines; Antirheumatic Agents; Arthritis, Rheumatoid; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Methotrexate; Middle Aged; Morpholines; Oxazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Syk Kinase; Treatment Outcome; Young Adult | 2014 |
Phase Ib dose-finding study of abiraterone acetate plus buparlisib (BKM120) or dactolisib (BEZ235) in patients with castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Asthenia; Chills; Diarrhea; Fever; Humans; Hyperglycemia; Imidazoles; Kallikreins; Male; Maximum Tolerated Dose; Middle Aged; Morpholines; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Quinolines; Stomatitis; Vomiting | 2017 |
Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Agents; Cohort Studies; Diarrhea; Disease-Free Survival; Female; Hematologic Diseases; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Morpholines; Neoplasm Proteins; Oxazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Salvage Therapy; Syk Kinase; Treatment Outcome | 2010 |
Efficacy of roflumilast in the COPD frequent exacerbator phenotype.
Topics: Aged; Aminopyridines; Benzamides; Cyclopropanes; Diarrhea; Disease Progression; Double-Blind Method; Endpoint Determination; Female; Humans; Incidence; Male; Middle Aged; Phenotype; Phosphodiesterase 4 Inhibitors; Pulmonary Disease, Chronic Obstructive; Treatment Outcome; Weight Loss | 2013 |
11 other study(ies) available for alpha-aminopyridine and Diarrhea
| Article | Year |
|---|---|
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: safety and patient-reported outcomes from the monarchE study.
Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Diarrhea; Female; Humans; Neoplasm Recurrence, Local; Patient Reported Outcome Measures; Quality of Life; Receptor, ErbB-2 | 2022 |
Abemaciclib-associated Diarrhea: An Exploratory Analysis of Real-life Data.
Topics: Aged; Aminopyridines; Benzimidazoles; Breast Neoplasms; Diarrhea; Female; Humans | 2023 |
In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels.
Topics: Aminopyridines; Animals; Antidiarrheals; Benzamides; Binding Sites; Calcium Channel Blockers; Carbachol; Castor Oil; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Diarrhea; Isoproterenol; Jejunum; Mice; Molecular Docking Simulation; Papaverine; Parasympatholytics; Phosphodiesterase 4 Inhibitors; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Rabbits; Verapamil | 2020 |
Prediction of severe neutropenia and diarrhoea in breast cancer patients treated with abemaciclib.
Topics: Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Diarrhea; Female; Humans; Neutropenia; Receptor, ErbB-2 | 2021 |
Intestinal Toxicity in Rats Following Administration of CDK4/6 Inhibitors Is Independent of Primary Pharmacology.
Topics: Aminopyridines; Animals; Benzimidazoles; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Diarrhea; Disease Models, Animal; Gene Expression Regulation; Male; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines; Rats; Rats, Sprague-Dawley | 2019 |
Patients' preferences for postmenopausal hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer treatments in Japan.
Topics: Aminopyridines; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Diarrhea; Female; Fulvestrant; Humans; Japan; Middle Aged; Patient Preference; Postmenopause; Progression-Free Survival; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Socioeconomic Factors; Surveys and Questionnaires | 2019 |
[Intractable diarrhoea and severe weight loss by roflumilast].
Topics: Aged; Aminopyridines; Animals; Anorexia; Benzamides; Bronchitis; Comorbidity; Cyclopropanes; Diarrhea; Drug Evaluation, Preclinical; Female; Gastrointestinal Tract; Hallucinations; Hospitalization; Humans; Patient Readmission; Phosphodiesterase Inhibitors; Polypharmacy; Product Surveillance, Postmarketing; Pulmonary Disease, Chronic Obstructive; Sleep Apnea Syndromes; Vomiting; Weight Loss | 2013 |
Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis.
Topics: Aminophenols; Aminopyridines; Animals; Benzamides; Bronchi; Bronchitis, Chronic; Cells, Cultured; Cyclic AMP; Cyclopropanes; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Intestinal Secretions; Intestine, Small; Membrane Potentials; Mice; Mucociliary Clearance; Phosphodiesterase 4 Inhibitors; Quinolones; Smoke; Smoking; Time Factors | 2014 |
New Drugs 2016, part 3.
Topics: Adenosine Monophosphate; Aminopyridines; Anti-Asthmatic Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiemetics; Benzodioxoles; Cholagogues and Choleretics; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycholic Acid; Diarrhea; Drug Approval; Imidazoles; Irritable Bowel Syndrome; Spiro Compounds | 2016 |
[New approaches to the treatment of chronic daily headache].
Topics: Adult; Aminopyridines; Analgesics; Attention Deficit Disorder with Hyperactivity; Constipation; Cyclohexanols; Diarrhea; Female; Headache Disorders; Humans; Male; Nausea; Pain Threshold; Treatment Outcome; Venlafaxine Hydrochloride | 2010 |
The potential role of racecadotril in the treatment of diarrhea associated with roflumilast.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aminopyridines; Antidiarrheals; Benzamides; Child; Cyclic AMP; Cyclopropanes; Diarrhea; Humans; Neprilysin; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive; Thiorphan | 2012 |