Page last updated: 2024-08-21

alpha-aminopyridine and Depression, Involutional

alpha-aminopyridine has been researched along with Depression, Involutional in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Burdick, KE; Fava, M; Johe, KK; Kay, G; Kumar, S; McIntyre, RS; Papakostas, GI1
Johe, K; Lee, Y; McIntyre, RS; Rong, C1
Alsiƶ, J; Bussey, TJ; Dewan, S; Heath, CJ; Nilsson, SRO; Phillips, BU; Robbins, TW; Saksida, LM1
Drouillard, A; Fava, M; Flynn, M; Hand, H; Hoeppner, B; Johe, K; Kashambwa, R; Kay, G; Martinson, MA; Papakostas, GI; Russo, P; Yeung, A1
Bilello, JA; Dickerson, BC; English, BA; Ereshefsky, L; Fava, M; Flynn, M; Freeman, MP; Gertsik, LG; Hoeppner, BB; Johe, K; Johnstone, J; Kinrys, G; Makris, N; Mischoulon, D; Thurmond, LM1
Bagby, RM; Carella, A; Dunn, E; Houle, S; Hussey, D; Lee, M; Meyer, JH; Praschak-Rieder, N; Willeit, M; Wilson, AA1

Reviews

1 review(s) available for alpha-aminopyridine and Depression, Involutional

ArticleYear
The neurogenic compound, NSI-189 phosphate: a novel multi-domain treatment capable of pro-cognitive and antidepressant effects.
    Expert opinion on investigational drugs, 2017, Volume: 26, Issue:6

    Topics: Adult; Aminopyridines; Animals; Antidepressive Agents; Bipolar Disorder; Cognition; Cognition Disorders; Depressive Disorder, Major; Hippocampus; Humans; Neurogenesis; Piperazines

2017

Trials

4 trial(s) available for alpha-aminopyridine and Depression, Involutional

ArticleYear
NSI-189 phosphate, a novel neurogenic compound, selectively benefits moderately depressed patients: A post-hoc analysis of a phase 2 study of major depressive disorder.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2020, Volume: 32, Issue:3

    Topics: Adult; Aminopyridines; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Neurogenesis; Piperazines; Severity of Illness Index

2020
A phase 2, double-blind, placebo-controlled study of NSI-189 phosphate, a neurogenic compound, among outpatients with major depressive disorder.
    Molecular psychiatry, 2020, Volume: 25, Issue:7

    Topics: Aminopyridines; Cognition; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Male; Middle Aged; Outpatients; Piperazines; Treatment Outcome

2020
A Phase 1B, randomized, double blind, placebo controlled, multiple-dose escalation study of NSI-189 phosphate, a neurogenic compound, in depressed patients.
    Molecular psychiatry, 2016, Volume: 21, Issue:10

    Topics: Adult; Aminopyridines; Biomarkers, Pharmacological; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2016
Tryptophan depletion and serotonin loss in selective serotonin reuptake inhibitor-treated depression: an [(18)F] MPPF positron emission tomography study.
    Biological psychiatry, 2004, Oct-15, Volume: 56, Issue:8

    Topics: Adult; Aminopyridines; Brain; Brain Mapping; Depressive Disorder, Major; Double-Blind Method; Fluorine Radioisotopes; Humans; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Radiochemistry; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2004

Other Studies

1 other study(ies) available for alpha-aminopyridine and Depression, Involutional

ArticleYear
Selective effects of 5-HT2C receptor modulation on performance of a novel valence-probe visual discrimination task and probabilistic reversal learning in mice.
    Psychopharmacology, 2018, Volume: 235, Issue:7

    Topics: Aminopyridines; Animals; Azepines; Depressive Disorder, Major; Discrimination Learning; Indoles; Male; Mice; Probability Learning; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Reversal Learning; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Task Performance and Analysis; Visual Perception

2018