alpha-aminopyridine has been researched along with Cell Transformation, Neoplastic in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Daga, H; Ebi, N; Fukuhara, T; Furuya, N; Goto, K; Hayashi, K; Hayashida, T; Ikeda, T; Ishii, G; Izumi, H; Kato, T; Kirita, K; Kobayashi, SS; Kodani, M; Kumagai, S; Kuyama, S; Liu, J; Matsumoto, S; Mori, S; Nakachi, I; Nakai, T; Nakamura, A; Niho, S; Nishino, K; Nosaki, K; Ohtsu, A; Okamoto, I; Sakai, T; Sakakibara-Konishi, J; Shibata, Y; Sugiyama, E; Taima, K; Tanaka, K; Udagawa, H; Watanabe, K; Yamasaki, A; Yoh, K; Zenke, Y | 1 |
| Chen, C; Fu, Y; Huang, T; Wang, S; Wang, X; Xu, M; Yin, X; Zhou, M | 1 |
| Cheng, W; Fang, S; Gong, YF; Guan, XY; Hu, L; Jiang, LX; Kong, FE; Li, HL; Li, L; Li, MM; Li, Y; Lin, G; Liu, M; Loong, JH; Ma, NF; Ma, S; Mo, JQ; Nam, Y; Ouyang, Q; Sun, Y; Tang, YQ; Wang, JG; Yan, Q; Yang, XD; Yuan, YF; Zhang, Y | 1 |
| Coleman, N; Popat, S; Wotherspoon, A; Yousaf, N | 1 |
| Bu, G; Cao, L; Hu, X; Huang, C; Li, H; Li, P; Lin, G; Lin, H; Luo, M; Wu, S; Xie, J; Xu, H; Yang, X; Yang, Y; Yu, Q; Zhang, J; Zhang, YW; Zhao, X; Zheng, C; Zhou, J | 1 |
| Choi, JH; Chung, YY; Jung, IH; Lim, GL; Park, SW; Park, YN | 1 |
| Kumar, V; Pandey, V | 1 |
| Aboagye, EO; Adejumo, T; Brickute, D; Carling, D; Carroll, L; Favicchio, R; Fortt, R; Gottlieb, E; Kaliszczak, M; Kalusa, A; Navaratnam, N; Nguyen, QD; Schug, Z; Tomasi, G; Trousil, S; Twyman, FJ | 1 |
| Baloglu, E; Crochiere, M; Das-Gupta, S; Landesman, Y; Minden, A; Rane, C; Senapedis, W | 1 |
| Ali, SM; Fernandez-Rocha, MY; Gitlitz, BJ; Lee, TK; Milliken, J; Ou, SI; Pavlick, D; Schrock, AB; Young, L; Zhu, VW | 1 |
| Buckley, AF; Cho, YJ; Eroshkin, A; Febbo, PG; Korshunov, A; McLendon, RE; Miller, CR; Moore, CE; Northcott, PA; Pei, Y; Pfister, SM; Read, TA; Schmitt, EM; Sun, JL; Taylor, MD; Tewari, AK; Wang, J; Wechsler-Reya, RJ; Westbrook, TF; Witt, H | 1 |
| Adamec, J; Baldridge, LA; Dudhgaonkar, S; Jedinak, A; Jiang, J; Lamb, JG; Loganathan, J; Sandusky, GE; Sliva, D; Terry, C | 1 |
| Mirsalis, JC | 1 |
13 other study(ies) available for alpha-aminopyridine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer.
Topics: Adenocarcinoma of Lung; Aminopyridines; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Humans; Lactams; Lung Neoplasms; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Proteins; Oncogene Proteins, Fusion; Pyrazoles; Receptor Protein-Tyrosine Kinases; Xenograft Model Antitumor Assays | 2021 |
miR-96 acts as a tumor suppressor via targeting the BCR-ABL1 oncogene in chronic myeloid leukemia blastic transformation.
Topics: 3' Untranslated Regions; Aminopyridines; Base Sequence; Benzamides; Blast Crisis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Decitabine; Down-Regulation; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MicroRNAs; Oncogenes; Protein Biosynthesis | 2019 |
A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets.
Topics: Aminopyridines; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cohort Studies; Disease-Free Survival; E2F1 Transcription Factor; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Hepatectomy; Hepatocytes; Human Embryonic Stem Cells; Humans; Hydroxyquinolines; Isoquinolines; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Male; Mice; Middle Aged; Prognosis; Pyridines; Pyrroles; Signal Transduction; Smad3 Protein; Xenograft Model Antitumor Assays | 2020 |
Transformation to neuroendocrine carcinoma as a resistance mechanism to lorlatinib.
Topics: Adult; Aminopyridines; Anaplastic Lymphoma Kinase; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; ErbB Receptors; Gene Rearrangement; Humans; Lactams; Lactams, Macrocyclic; Liver Neoplasms; Lung Neoplasms; Male; Molecular Targeted Therapy; Mutation; Neoplasm Metastasis; Neoplasm Staging; Pyrazoles; Tomography, X-Ray Computed | 2019 |
Cyclin-dependent kinase 5 decreases in gastric cancer and its nuclear accumulation suppresses gastric tumorigenesis.
Topics: Aminopyridines; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 5; Exportin 1 Protein; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Karyopherins; Lymphatic Metastasis; Male; Maleimides; Mice; Mice, Inbred BALB C; Prognosis; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stomach; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis.
Topics: Aminopyridines; Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cyclic S-Oxides; Disease Models, Animal; Enzyme Activation; Humans; Inflammation; Interleukin-6; Janus Kinases; Liver; Liver Neoplasms; Morpholines; Niclosamide; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; STAT3 Transcription Factor; Zebrafish; Zebrafish Proteins | 2015 |
Stabilization of SIRT7 deacetylase by viral oncoprotein HBx leads to inhibition of growth restrictive RPS7 gene and facilitates cellular transformation.
Topics: Aminopyridines; Animals; Cell Transformation, Neoplastic; Hep G2 Cells; Hepatocytes; Host-Pathogen Interactions; Humans; Mice, Transgenic; Promoter Regions, Genetic; Protein Stability; Ribosomal Proteins; Sirtuins; Thiocyanates; Trans-Activators; Up-Regulation; Viral Regulatory and Accessory Proteins | 2015 |
The novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.
Topics: Aminopyridines; Animals; Apoptosis; Cell Line, Tumor; Cell Membrane; Cell Transformation, Neoplastic; Choline; Choline Kinase; Citrate (si)-Synthase; Endoplasmic Reticulum Stress; Female; Fluorescent Antibody Technique; G1 Phase Cell Cycle Checkpoints; Humans; Metabolomics; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Phosphatidylcholines; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyridinium Compounds; Reactive Oxygen Species; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
A novel orally bioavailable compound KPT-9274 inhibits PAK4, and blocks triple negative breast cancer tumor growth.
Topics: Acrylamides; Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Mice; p21-Activated Kinases; Phosphorylation; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Dual occurrence of ALK G1202R solvent front mutation and small cell lung cancer transformation as resistance mechanisms to second generation ALK inhibitors without prior exposure to crizotinib. Pitfall of solely relying on liquid re-biopsy?
Topics: Adult; Aged; Aminopyridines; Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Crizotinib; Disease Progression; Drug Resistance, Neoplasm; Fatal Outcome; Female; Humans; Lactams; Lactams, Macrocyclic; Liquid Biopsy; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplastic Cells, Circulating; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Retinoblastoma Binding Proteins; Small Cell Lung Carcinoma; Ubiquitin-Protein Ligases | 2017 |
An animal model of MYC-driven medulloblastoma.
Topics: Aminopyridines; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cerebellar Neoplasms; Cerebellum; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Genes, p53; Imidazoles; Medulloblastoma; Mice; Morpholines; Neural Stem Cells; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-myc; Quinolines; TOR Serine-Threonine Kinases | 2012 |
Mushroom Ganoderma lucidum prevents colitis-associated carcinogenesis in mice.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Dextran Sulfate; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Imidazoles; Inflammation; Macrophages; Mice; Neoplasms, Experimental; Plant Extracts; Reishi | 2012 |
Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene.
Topics: Aminopyridines; Animals; Biotransformation; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Damage; DNA Repair; Female; Liver; Male; Methapyrilene; Mice; Mutation; Rats; Salmonella typhimurium | 1987 |