alpha-aminopyridine has been researched along with Carcinoma, Epidermoid in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 13 (81.25) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| He, WB; Huang, KQ; Liu, JN; Ma, ZL; Su, RJ | 1 |
| Barlesi, F; Besse, B; Demedts, I; Frimodt-Moller, B; Fuentes Pradera, J; Gazzah, A; Kim, JS; Robinet, G; Soldatenkova, V; Vansteenkiste, J | 1 |
| Byeon, HK; Cho, BC; Choi, JW; Hong, MH; Jung, I; Kang, HN; Kim, DH; Kim, HR; Kim, J; Kim, JH; Koh, YW; Lee, H; Lim, SM; Paik, S; Park, AY; Park, YM; Pyo, KH; Shin, EJ; Yoon, SO; Yun, MR | 1 |
| Chen, JH; Chuang, FC; Hwang, TZ; Su, YC; Wang, CC; Yeh, SA | 1 |
| Cho, BC; Choi, HM; Hong, MH; Joo, HS; Kang, HN; Kim, DH; Kim, HR; Lee, Y; Yoon, SO; Yun, MR | 1 |
| Alifano, M; Barrin, S; Bercovici, N; Biton, J; Damotte, D; Donnadieu, E; Feuillet, V; Guérin, M; Kantari-Mimoun, C; Lemoine, J; Lupo, A; Ouakrim, H; Peranzoni, E; Régnier, F; Vimeux, L | 1 |
| Huang, P; Li, Q; Liu, X; Tong, D; Wu, H; Zhang, F | 1 |
| Bradley, KM; Campo, L; Fenwick, JD; Gleeson, FV; Green, M; Higgins, GS; Horne, A; Macpherson, RE; Maughan, TS; McCole, MG; McGowan, DR; McKenna, WG; Mohammed, S; Muschel, RJ; Ng, SM; Panakis, N; Prevo, R; Skwarski, M; Strauss, VY; Stuart, R; Tacconi, EMC; Vallis, KA | 1 |
| Ando, Y; Doi, T; Inada-Inoue, M; Kakizume, T; Mitsuma, A; Ohtsu, A; Quadt, C; Robson, M; Sato, M; Suenaga, N; Yoshino, T | 1 |
| Alfieri, RR; Ardizzoni, A; Bonelli, MA; Caffarra, C; Cavazzoni, A; Cretella, D; Falco, A; Frati, C; Fumarola, C; Galetti, M; La Monica, S; Lagrasta, CA; Madeddu, D; Petronini, PG; Quaini, F; Rossetti, P; Saccani, F; Tiseo, M | 1 |
| Anderton, SM; Brunton, VG; Byron, A; Canel, M; Frame, MC; Gilbert, N; Gómez-Cuadrado, L; Lund, T; Maniati, E; McPherson, RC; Muir, M; Nibbs, RJ; Pachter, JA; Ring, JE; Serrels, A; Serrels, B; Sims, AH; von Kriegsheim, A | 1 |
| Ahn, JS; Ahn, MJ; Bae, YH; Koh, J; Ku, BM; Lee, SH; Park, K; Sun, JM; Yi, SY | 1 |
| Baloglu, E; Chen, Y; Chien, WW; Ding, LW; Hazawa, M; Jiang, YY; Kanojia, D; Koeffler, HP; Lin, DC; Mayakonda, A; Senapedis, W; Shang, L; Tyner, JW; Wang, MR; Xiao, JF; Xu, L; Xu, X; Yang, H | 1 |
| Bozec, A; Chamorey, E; Ebran, N; Gautier, M; Marcie, S; Milano, G; Penault-Llorca, F; Radosevic-Robin, N; Yahia, HB | 1 |
| Amin, AR; Anisuzzaman, AS; Chen, Z; Chen, ZG; Haque, A; Rahman, MA; Shin, DM; Wang, D; Zhang, C | 1 |
| Aimone, P; Alyasova, A; Barone, C; Chakravartty, A; Chol, M; Dechaphunkul, A; Erfán, J; Faivre, S; Hirawat, S; Karpenko, A; Kasper, S; Kim, SB; Kiss, LA; Li, SH; Licitra, L; Lin, JC; Mesía, R; Nagarkar, R; Ochsenreither, S; Remenár, É; Soulières, D; Tamás, L; Turri, S | 1 |
4 trial(s) available for alpha-aminopyridine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
A phase 1b study of necitumumab in combination with abemaciclib in patients with stage IV non-small cell lung cancer.
Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Aminopyridines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Survival Rate; Tissue Distribution; Treatment Outcome | 2019 |
Buparlisib with thoracic radiotherapy and its effect on tumour hypoxia: A phase I study in patients with advanced non-small cell lung carcinoma.
Topics: Adenocarcinoma of Lung; Aged; Aminopyridines; Anorexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Fatigue; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Misonidazole; Morpholines; Nausea; Phosphoinositide-3 Kinase Inhibitors; Positron Emission Tomography Computed Tomography; Radiation-Sensitizing Agents; Radiotherapy; Tumor Hypoxia | 2019 |
Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors.
Topics: Adult; Aged; Aminopyridines; Antineoplastic Agents; Area Under Curve; Carcinoma, Squamous Cell; Colorectal Neoplasms; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Japan; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Treatment Outcome; Young Adult | 2014 |
Buparlisib and paclitaxel in patients with platinum-pretreated recurrent or metastatic squamous cell carcinoma of the head and neck (BERIL-1): a randomised, double-blind, placebo-controlled phase 2 trial.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Double-Blind Method; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; International Agencies; Male; Middle Aged; Morpholines; Neoplasm Recurrence, Local; Neoplasm Staging; Paclitaxel; Platinum; Prognosis; Survival Rate | 2017 |
12 other study(ies) available for alpha-aminopyridine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
[Effect of Met kinase inhibitor BMS-777607 on proliferation and apoptosis of tongue cell line CAL 27 squamous cell carcinoma].
Topics: Aminopyridines; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridones; Tongue; Tongue Neoplasms | 2021 |
Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer.
Topics: Afatinib; Aminopyridines; Animals; Biopsy; Carcinoma, Squamous Cell; Gene Amplification; Gene Regulatory Networks; Genetic Variation; Head and Neck Neoplasms; High-Throughput Nucleotide Sequencing; Humans; Methotrexate; Mice; Morpholines; Papillomavirus Infections; Patient-Specific Modeling; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2020 |
PI3k inhibitors (BKM120 and BYL719) as radiosensitizers for head and neck squamous cell carcinoma during radiotherapy.
Topics: Aminopyridines; Carcinoma, Squamous Cell; Cell Line, Tumor; Head and Neck Neoplasms; Humans; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Radiation-Sensitizing Agents; Thiazoles | 2021 |
ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.
Topics: Aminopyridines; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Autocrine Communication; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Female; Head and Neck Neoplasms; Humans; Interleukin-6; MAP Kinase Signaling System; Mice; Mice, Inbred NOD; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyridones; Pyrimidinones; Receptors, Interleukin-6; RNA, Small Interfering; Squamous Cell Carcinoma of Head and Neck; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2018 |
Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti-PD-1 treatment.
Topics: Aminopyridines; Animals; Carcinoma, Squamous Cell; CD8-Positive T-Lymphocytes; Follow-Up Studies; Macrophages; Mice; Programmed Cell Death 1 Receptor; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Retrospective Studies; Xenograft Model Antitumor Assays | 2018 |
EGFR-mediated signaling pathway influences the sensitivity of oral squamous cell carcinoma to JQ1.
Topics: Aminopyridines; Analysis of Variance; Animals; Antineoplastic Agents; Apoptosis; Azepines; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Female; Gene Knockdown Techniques; Humans; Mice; Morpholines; Mouth Neoplasms; Nuclear Proteins; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Transcription Factors; Triazoles; Xenograft Model Antitumor Assays | 2018 |
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations.
Topics: Aminopyridines; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Imidazoles; Lung Neoplasms; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays | 2015 |
Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.
Topics: Aminopyridines; Animals; Carcinoma, Squamous Cell; Chemokine CCL5; Disease Models, Animal; Focal Adhesion Protein-Tyrosine Kinases; Humans; Keratinocytes; Mice; Mice, Nude; Skin Neoplasms; T-Lymphocytes, Regulatory; Transcription, Genetic; Tumor Escape | 2015 |
The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma.
Topics: Aminopyridines; Animals; Apoptosis; Benzimidazoles; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Therapy, Combination; Everolimus; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma.
Topics: Acrylamides; Adaptor Proteins, Signal Transducing; Aminopyridines; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Core Binding Factor Alpha 2 Subunit; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Female; Gene Expression; Gene Expression Profiling; High-Throughput Screening Assays; HSP40 Heat-Shock Proteins; Humans; Mice; Neoplasm Transplantation; Oncogenes; p21-Activated Kinases; Phenylenediamines; Phosphoproteins; Pyrimidines; Sequence Analysis, RNA; Sterol Regulatory Element Binding Protein 2; Transcription Factors; Transcriptome; YAP-Signaling Proteins | 2017 |
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer.
Topics: Aminopyridines; Animals; Antineoplastic Agents, Immunological; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Disease Models, Animal; Female; Head and Neck Neoplasms; Mice; Mice, Nude; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays | 2017 |
Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Cytoprotection; Drug Resistance, Neoplasm; Drug Synergism; Erlotinib Hydrochloride; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Mice; Morpholines; Proto-Oncogene Proteins c-akt; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2017 |