Page last updated: 2024-08-21

alpha-aminopyridine and Bone Neoplasms

alpha-aminopyridine has been researched along with Bone Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Bao, H; Wang, D1
Hu, X; Jian, C; Li, D; Li, P; Li, Y; Li, Z; Yi, W; Yu, A; Yuan, Y; Zhao, Y1
Grellety, T; Meynard, L1
Brunac, AC; Castex, MP; Gomez-Brouchet, A; Guillemot, D; Karanian, M; Laprie, A; Laurent, C; Le Guellec, S; Le Loarer, F; Pierron, G1
Ferreira, LP; Gaspar, VM; Mano, JF; Monteiro, MV1
Bavelloni, A; Blalock, W; Cocco, L; Faenza, I; Focaccia, E; Orsini, A; Piazzi, M; Ramazzotti, G1
Bao, X; Lu, S; Niu, X; Wang, M; Wang, Q; Wang, S; Wang, Y; Xu, L; Zhang, J1
Alexe, G; Berman, JN; Boxer, MB; Conway Saur, A; Crompton, BD; Davis, MI; Guha, R; Hall, MD; Hughes, E; Hwang, EE; Kung, A; Lemieux, ME; McKnight, C; Melong, N; O'Neill, AF; Shen, M; Stegmaier, K; Veinotte, CJ; Wang, A; Wang, S; Wuerthele, K; Xu, X1
Cheng, Y; Cristofanilli, M; Cui, S; Feng, J; Gao, J; Geng, C; Gu, K; Hu, X; Jiang, Z; Li, W; Liu, T; Lu, X; Ning, Z; Ouyang, Q; Ouyang, T; Pan, Y; Sun, T; Sun, Y; Tong, Z; Wang, H; Wang, S; Wang, X; Yin, Y; Zhang, Q1
Avnet, S; Baldini, N; Di Pompo, G; Lattanzi, G; Mai, A; Rotili, D; Salerno, M; Valente, S; Zwergel, C1
Burton, EA; Chartier, S; Habets, G; Jimenez-Andrade, JM; Lin, PS; Mantyh, PW; Thompson, ML; Tsai, J; West, BL1
Cooke, I; Goodchild, CS; Kolosov, A; Williams, ED1

Trials

1 trial(s) available for alpha-aminopyridine and Bone Neoplasms

ArticleYear
Tucidinostat plus exemestane for postmenopausal patients with advanced, hormone receptor-positive breast cancer (ACE): a randomised, double-blind, placebo-controlled, phase 3 trial.
    The Lancet. Oncology, 2019, Volume: 20, Issue:6

    Topics: Aminopyridines; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Breast Neoplasms; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Salvage Therapy; Survival Rate; Treatment Outcome

2019

Other Studies

11 other study(ies) available for alpha-aminopyridine and Bone Neoplasms

ArticleYear
Abemaciclib is synergistic with doxorubicin in osteosarcoma pre-clinical models via inhibition of CDK4/6-Cyclin D-Rb pathway.
    Cancer chemotherapy and pharmacology, 2022, Volume: 89, Issue:1

    Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Cyclin D; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Doxorubicin; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Mice, SCID; Osteosarcoma; Retinoblastoma Protein; Xenograft Model Antitumor Assays

2022
Chidamide augment sorafenib-derived anti-tumor activities in human osteosarcoma cells lines and xenograft mouse model.
    Medical oncology (Northwood, London, England), 2022, Apr-28, Volume: 39, Issue:5

    Topics: Aminopyridines; Animals; Benzamides; Bone Neoplasms; Cell Line, Tumor; Heterografts; Histone Deacetylase Inhibitors; Humans; Mice; Osteosarcoma; Sorafenib

2022
CDK 4/6 inhibitor successful rechallenge after limiting hepatic toxicity.
    The breast journal, 2020, Volume: 26, Issue:2

    Topics: Alanine Transaminase; Aminopyridines; Aromatase Inhibitors; Aspartate Aminotransferases; Bone Neoplasms; Breast Neoplasms; Carcinoma, Lobular; Chemical and Drug Induced Liver Injury; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Substitution; Drug Therapy, Combination; Female; Humans; Letrozole; Middle Aged; Piperazines; Protein Kinase Inhibitors; Purines; Pyridines

2020
The combination of radiotherapy and ALK inhibitors is effective in the treatment of intraosseous rhabdomyosarcoma with FUS-TFCP2 fusion transcript.
    Pediatric blood & cancer, 2020, Volume: 67, Issue:5

    Topics: Adolescent; Aminopyridines; Anaplastic Lymphoma Kinase; Bone Neoplasms; Carbazoles; Chemoradiotherapy; DNA-Binding Proteins; Female; Humans; Lactams; Lactams, Macrocyclic; Oncogene Proteins, Fusion; Piperidines; Pyrazoles; Rhabdomyosarcoma; RNA-Binding Protein FUS; Transcription Factors

2020
Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response.
    Biomaterials science, 2020, Mar-31, Volume: 8, Issue:7

    Topics: Aminopyridines; Biomimetic Materials; Bone Neoplasms; Cell Aggregation; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Matrix; Humans; Lactams; Lactams, Macrocyclic; Models, Biological; Osteosarcoma; Pyrazoles; Spheroids, Cellular; Tumor Microenvironment

2020
Therapeutic potential of nvp-bkm120 in human osteosarcomas cells.
    Journal of cellular physiology, 2019, Volume: 234, Issue:7

    Topics: Aminopyridines; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Morpholines; Osteosarcoma; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2019
The PI3K inhibitor buparlisib suppresses osteoclast formation and tumour cell growth in bone metastasis of lung cancer, as evidenced by multimodality molecular imaging.
    Oncology reports, 2019, Volume: 41, Issue:5

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Bone and Bones; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Molecular Imaging; Morpholines; Osteoclasts; Positron Emission Tomography Computed Tomography; Single Photon Emission Computed Tomography Computed Tomography; Treatment Outcome; X-Ray Microtomography

2019
High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 07-15, Volume: 25, Issue:14

    Topics: Aminopyridines; Animals; Apoptosis; Aurora Kinase B; Bone Neoplasms; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; Female; Focal Adhesion Kinase 1; High-Throughput Screening Assays; Humans; Indoles; Mice; Mice, Nude; Organophosphates; Protein Kinase Inhibitors; Quinazolines; Sarcoma, Ewing; Small Molecule Libraries; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zebrafish

2019
Novel histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in sarcoma cancer stem cells.
    Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9

    Topics: Aminopyridines; Apoptosis; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplastic Stem Cells; Osteogenesis; Osteosarcoma; Pyrimidinones; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Structure-Activity Relationship

2015
Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer.
    Pain, 2015, Volume: 156, Issue:9

    Topics: Aminopyridines; Analgesics; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Dogs; Formaldehyde; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pain; Pain Measurement; Prostatic Neoplasms; Protein Kinases; Pyrroles; Rats; Rats, Sprague-Dawley

2015
Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:11

    Topics: Aminopyridines; Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Hyperalgesia; Male; Morphine; Pain; Prostatic Neoplasms; Rats; Rats, Wistar

2012