Page last updated: 2024-08-21

alpha-aminopyridine and Autoimmune Thrombocytopenia

alpha-aminopyridine has been researched along with Autoimmune Thrombocytopenia in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (10.00)	29.6817
2010's	8 (40.00)	24.3611
2020's	10 (50.00)	2.80

Authors

Authors	Studies
Dierickx, D; Neefs, J	1
Hirota, T; Ieiri, I; Matsukane, R; Suetsugu, K	1
Cooper, N; Ghanima, W; Hill, QA; Kessler, C; Markovtsov, V; Nicolson, PL	1
Bussel, JB; Izak, M; Lee, EJ	1
Kapur, R	1
McDonald, V; Newland, A	1
Boccia, R; Boxer, MA; Bussel, JB; Cooper, N; Ghanima, W; Hill, QA; Sholzberg, M; Tarantino, MD; Todd, LK; Tong, S	1
Gernsheimer, T; Ghanima, W; Kuter, DJ	1
Paik, J	1
Allegra, A; Caserta, S; Innao, V; Musolino, C; Zaccuri, AM	1
Bussel, JB; Lee, EJ; McDonald, V; Newland, A	1
Giovannini, M; Niscola, P; Scaramucci, L	1
Arnold, DM; Bussel, J; Cooper, N; Duliege, AM; Grossbard, E; Hellmann, A; Homenda, W; Khalafallah, AA; Markovtsov, V; Mayer, J; Sivcheva, L; Treliński, J; Windyga, J; Zaja, F; Zayed, H	1
Markham, A	1
Han, PP; Hou, M; Hou, Y; Jing, FM; Li, DQ; Li, LZ; Li, P; Liu, XG; Liu, Y; Ma, YH; Peng, J; Sun, T; Zhao, HY; Zhao, YJ; Zhou, H	1
Arnold, DM; Boxer, MA; Bussel, JB; Cooper, N; Duliege, AM; Mayer, J; Tong, S; Zayed, H	1
Berliner, N; Connell, NT	1
Gebru, T; Moore, DC; Muslimani, A	1
Bussel, JB; Crow, AR; Grossbard, E; Lazarus, AH; Podolanczuk, A	1
Bajpai, M	1

Reviews

9 review(s) available for alpha-aminopyridine and Autoimmune Thrombocytopenia

Article	Year
Evaluating fostamatinib disodium as a treatment option for immune thrombocytopenia in adult patients. Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:8 Topics: Adult; Aminopyridines; Humans; Morpholines; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Thrombocytopenia	2022
Clinical Pharmacokinetics and Pharmacodynamics of Fostamatinib and Its Active Moiety R406. Clinical pharmacokinetics, 2022, Volume: 61, Issue:7 Topics: Aminopyridines; ATP Binding Cassette Transporter, Subfamily G, Member 2; Humans; Morpholines; Neoplasm Proteins; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines	2022
Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib. Platelets, 2023, Volume: 34, Issue:1 Topics: Aminopyridines; COVID-19; Humans; Oxazines; Protein Kinase Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Syk Kinase	2023
Fostamatinib: a review of its clinical efficacy and safety in the management of chronic adult immune thrombocytopenia. Immunotherapy, 2020, Volume: 12, Issue:18 Topics: Aminopyridines; Humans; Morpholines; Purpura, Thrombocytopenic, Idiopathic; Pyrimidines; Treatment Outcome	2020
Fostamatinib: A Review in Chronic Immune Thrombocytopenia. Drugs, 2021, Volume: 81, Issue:8 Topics: Aminopyridines; Chronic Disease; Clinical Trials, Phase III as Topic; Humans; Morpholines; Purpura, Thrombocytopenic, Idiopathic; Pyrimidines; Randomized Controlled Trials as Topic; Syk Kinase	2021
Immune thrombocytopenia: options and new perspectives. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Oct-01, Volume: 32, Issue:7 Topics: Aminopyridines; Antibodies, Monoclonal, Humanized; COVID-19; Histocompatibility Antigens Class I; Humans; Immunosuppressive Agents; Morpholines; Protein Kinase Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Pyrimidines; Receptors, Fc; Receptors, Thrombopoietin; SARS-CoV-2; Syk Kinase; Thiazoles; Thiophenes	2021
Fostamatinib for persistent/chronic adult immune thrombocytopenia. Immunotherapy, 2018, Volume: 10, Issue:1 Topics: Adult; Aminopyridines; Blood Platelets; Chronic Disease; Humans; Immunotherapy; Morpholines; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Recurrence; Signal Transduction; Syk Kinase	2018
Fostamatinib: First Global Approval. Drugs, 2018, Volume: 78, Issue:9 Topics: Aminopyridines; Anemia, Hemolytic, Autoimmune; Drug Approval; Glomerulonephritis, IGA; Humans; Morpholines; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Syk Kinase; Treatment Outcome	2018
Fostamatinib for the treatment of chronic immune thrombocytopenia. Blood, 2019, 05-09, Volume: 133, Issue:19 Topics: Aminopyridines; Clinical Trials, Phase III as Topic; Humans; Morpholines; Oxazines; Protein Kinase Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines	2019

Trials

4 trial(s) available for alpha-aminopyridine and Autoimmune Thrombocytopenia

Article	Year
Fostamatinib is an effective second-line therapy in patients with immune thrombocytopenia. British journal of haematology, 2020, Volume: 190, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Female; Humans; Male; Middle Aged; Morpholines; Oxazines; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines	2020
Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo-controlled trials. American journal of hematology, 2018, Volume: 93, Issue:7 Topics: Adult; Aminopyridines; Blood Platelets; Chronic Disease; Humans; Morpholines; Oxazines; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Splenectomy; Syk Kinase; Treatment Outcome	2018
Long-term fostamatinib treatment of adults with immune thrombocytopenia during the phase 3 clinical trial program. American journal of hematology, 2019, Volume: 94, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Oxazines; Platelet Count; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Time Factors	2019
Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk. Blood, 2009, Apr-02, Volume: 113, Issue:14 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aminopyridines; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Middle Aged; Morpholines; Oxazines; Pilot Projects; Prodrugs; Protein-Tyrosine Kinases; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Syk Kinase; Treatment Outcome	2009

Other Studies

7 other study(ies) available for alpha-aminopyridine and Autoimmune Thrombocytopenia

Article	Year
Long-term sustained response to fostamatinib in two patients with chronic refractory immune thrombocytopenia (ITP). British journal of haematology, 2020, Volume: 189, Issue:2 Topics: Adult; Aged; Aminopyridines; Chronic Disease; Female; Humans; Morpholines; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines	2020
Fine-tuning the treatment toolbox of immune thrombocytopenia: fostamatinib as a second-line therapy. British journal of haematology, 2020, Volume: 190, Issue:6 Topics: Aminopyridines; Humans; Morpholines; Oxazines; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Thrombocytopenia	2020
How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment. Blood, 2021, 05-20, Volume: 137, Issue:20 Topics: Adrenal Cortex Hormones; Adult; Aged; Aminopyridines; Combined Modality Therapy; Disease Management; Drug Substitution; Drug Tolerance; Elective Surgical Procedures; Female; Hemorrhage; Humans; Immunosuppressive Agents; Maintenance Chemotherapy; Male; Middle Aged; Morpholines; Preoperative Care; Purpura, Thrombocytopenic, Idiopathic; Pyrimidines; Randomized Controlled Trials as Topic; Receptors, Fc; Receptors, Thrombopoietin; Recombinant Fusion Proteins; Remission Induction; Rituximab; Splenectomy; Thrombopoietin; Young Adult	2021
Spleen tyrosine kinase inhibition: a new promising approach to chronic and refractory immune thrombocytopenia. Immunotherapy, 2018, Volume: 10, Issue:1 Topics: Aminopyridines; Clinical Trials, Phase III as Topic; Humans; Morpholines; Oxazines; Prodrugs; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Recurrence; Syk Kinase	2018
Low-dose chidamide restores immune tolerance in ITP in mice and humans. Blood, 2019, 02-14, Volume: 133, Issue:7 Topics: Acetylation; Adult; Aged; Aminopyridines; Animals; Benzamides; CTLA-4 Antigen; Dose-Response Relationship, Drug; Female; Forkhead Transcription Factors; Humans; Immune Tolerance; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Middle Aged; Prognosis; Purpura, Thrombocytopenic, Idiopathic; T-Lymphocytes, Regulatory; Young Adult	2019
Fostamatinib for the treatment of immune thrombocytopenia in adults. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2019, May-17, Volume: 76, Issue:11 Topics: Administration, Oral; Aminopyridines; Blood Platelets; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Humans; Morpholines; Oxazines; Platelet Count; Protein Kinase Inhibitors; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Receptors, Fc; Signal Transduction; Syk Kinase; Treatment Outcome	2019
Fostamatinib, a Syk inhibitor prodrug for the treatment of inflammatory diseases. IDrugs : the investigational drugs journal, 2009, Volume: 12, Issue:3 Topics: Aminopyridines; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Lymphoma; Molecular Structure; Morpholines; Oxazines; Prodrugs; Protein-Tyrosine Kinases; Purpura, Thrombocytopenic, Idiopathic; Pyridines; Pyrimidines; Structure-Activity Relationship; Syk Kinase	2009