alpha-aminopyridine has been researched along with Anxiety in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 12 (42.86) | 29.6817 |
| 2010's | 13 (46.43) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Corrêa, FM; Fortaleza, EA; Matthiesen, M; Mendes, LD; Spiacci, A; Zangrossi, H | 1 |
| Bertagna, NB; Cruz, FC; Dos Santos, PGC; Fernandes, GJD; Miguel, TT; Queiroz, RM | 1 |
| Goralski, JL; McKinzie, CJ; Noah, TL; Prieur, MB; Retsch-Bogart, GZ | 1 |
| de Andrade, TGCS; Hernandes, PM; Sant'Ana, AB; Vicente, MA; Vilela-Costa, HH; Zangrossi, H | 1 |
| Gomes, KS; Miguel, TT; Nunes-de-Souza, RL | 1 |
| Greenwood-Van Meerveld, B; Schulkin, J; Tran, L | 1 |
| Der-Ghazarian, T; Neisewander, JL; Pentkowski, NS; Pockros-Burgess, LA | 1 |
| Gerlai, R; Markovic, S; Muraleetharan, A; Nowicki, M; Tran, S | 1 |
| Faria, MP; Gomes, KS; Miguel, TT; Nunes-de-Souza, RL | 1 |
| Cipriano, AC; Gomes, KS; Nunes-de-Souza, RL | 1 |
| Imanishi, T; Kondo, M; Koyama, T; Ohyama, M; Yamauchi, M | 1 |
| Fleshner, M; Greenwood, BN; Strong, PV | 1 |
| Amat, J; Christianson, JP; Fleshner, M; Greenwood, BN; Maier, SF; Paul, ED; Ragole, T; Strong, PV; Watkins, LR | 1 |
| Greenwood-Van Meerveld, B; Myers, B | 1 |
| Jiang, X; Li, Q; Luo, T; Wang, J | 1 |
| Christianson, JP; Drugan, RC; Flyer, JG; Maier, SF; Watkins, LR | 1 |
| Breese, GR; Knapp, DJ; Moy, SS; Overstreet, DH | 2 |
| Campbell, BM; Merchant, KM | 1 |
| Bagdy, G; Detari, L; Gyongyosi, N; Jakus, R; Kantor, S; Molnar, E; Toth, A | 1 |
| Avison, MJ; Deutch, AY; Gore, JC; Gresch, PJ; Hackler, EA; Sanders-Bush, E; Sengupta, S; Turner, GH | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH | 1 |
| Brooks, L; Fleshner, M; Greenwood, BN; Strong, PV | 1 |
| Cao, BJ; Rodgers, RJ | 1 |
| Griebel, G; Perrault, G; Rodgers, RJ; Sanger, DJ | 1 |
| Kerr, TM; Parsons, LH; Tecott, LH | 1 |
| Anheuer, ZE; Bagdy, G; Graf, M; Kantor, S; Modos, EA | 1 |
| Ballard, TM; Higgins, GA; Martin, JR | 1 |
28 other study(ies) available for alpha-aminopyridine and Anxiety
| Article | Year |
|---|---|
Serotonin 2C receptors in the basolateral amygdala mediate the anxiogenic effect caused by serotonergic activation of the dorsal raphe dorsomedial subnucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anxiety; Basolateral Nuclear Complex; Dorsal Raphe Nucleus; Electric Stimulation; Indoles; Kainic Acid; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2020 |
Involvement of the ventral, but not dorsal, hippocampus in anxiety-like behaviors in mice exposed to the elevated plus maze: participation of CRF1 receptor and PKA pathway.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Cobalt; Cyclic AMP-Dependent Protein Kinases; Hippocampus; Isoquinolines; Male; Maze Learning; Mice; Microinjections; Motor Activity; Protein Kinase Inhibitors; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Sulfonamides | 2021 |
Worsening anxiety and depression after initiation of lumacaftor/ivacaftor combination therapy in adolescent females with cystic fibrosis.
Topics: Adolescent; Aminophenols; Aminopyridines; Antidepressive Agents; Anxiety; Benzodioxoles; Child; Cognitive Behavioral Therapy; Cystic Fibrosis; Depression; Drug Combinations; Female; Humans; Membrane Transport Modulators; Quinolones; Suicidal Ideation; Suicide, Attempted; Withholding Treatment | 2017 |
Role of 5-HT2C receptors of the dorsal hippocampus in the modulation of anxiety- and panic-related defensive responses in rats.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Ethylamines; Hippocampus; Imipramine; Indoles; Male; Maze Learning; Microinjections; Panic; Piperazines; Punishment; Pyrazines; Rats; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists | 2019 |
Tonic modulation of anxiety-like behavior by corticotropin-releasing factor (CRF) type 1 receptor (CRF1) within the medial prefrontal cortex (mPFC) in male mice: role of protein kinase A (PKA).
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Isoquinolines; Male; Mice; Microinjections; Prefrontal Cortex; Protein Kinase Inhibitors; Receptors, Corticotropin-Releasing Hormone; Sulfonamides | 2014 |
Importance of CRF receptor-mediated mechanisms of the bed nucleus of the stria terminalis in the processing of anxiety and pain.
Topics: Aminopyridines; Animals; Anxiety; Central Nervous System Agents; Comorbidity; Exploratory Behavior; Hyperalgesia; Male; Maze Learning; Pain; Pain Threshold; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Sensory Gating; Septal Nuclei; Stress, Psychological | 2014 |
Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behavior.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Indoles; Male; Maze Learning; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2014 |
Serotonin antagonists induce anxiolytic and anxiogenic-like behavior in zebrafish in a receptor-subtype dependent manner.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Ketanserin; Ondansetron; Piperazines; Pyridines; Receptors, Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT3 Receptor Antagonists; Zebrafish | 2014 |
Anxiety-like responses induced by nitric oxide within the BNST in mice: Role of CRF1 and NMDA receptors.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Corticotropin-Releasing Hormone; Freezing Reaction, Cataleptic; Male; Maze Learning; Mice; Neurons; Nitric Oxide; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Stress, Psychological; Triazenes | 2016 |
CRF receptor type 1 (but not type 2) located within the amygdala plays a role in the modulation of anxiety in mice exposed to the elevated plus maze.
Topics: Aminopyridines; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Corticotropin-Releasing Hormone; Male; Maze Learning; Mice; Peptide Fragments; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2016 |
Asenapine reduces anxiety-related behaviours in rat conditioned fear stress model.
Topics: Aminopyridines; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; Buspirone; Clozapine; Conditioning, Classical; Dibenzocycloheptenes; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Fear; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Indoles; Male; Olanzapine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2016 |
The effects of the selective 5-HT(2C) receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats.
Topics: Aminopyridines; Animals; Anxiety; Escape Reaction; Freezing Reaction, Cataleptic; Helplessness, Learned; Indoles; Injections, Intraperitoneal; Male; Piperazines; Pyrazines; Rats; Rats, Inbred F344; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological | 2009 |
5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amygdala; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Disease Models, Animal; Electroshock; Indoles; Microdialysis; Rats; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior; Stress Disorders, Traumatic | 2010 |
Elevated corticosterone in the amygdala leads to persistent increases in anxiety-like behavior and pain sensitivity.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Colon; Corticosterone; Drug Implants; Injections, Intraventricular; Male; Maze Learning; Pain Threshold; Rats; Rats, Inbred F344 | 2010 |
Anxiolytic effects of 5-HT₁A receptors and anxiogenic effects of 5-HT₂C receptors in the amygdala of mice.
Topics: Adenoviridae; Aminopyridines; Amphetamines; Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Autoradiography; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Iodine Radioisotopes; Maze Learning; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides, Antisense; Piperazines; Protein Binding; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2012 |
Anxiogenic effects of brief swim stress are sensitive to stress history.
Topics: Aminopyridines; Animals; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Exploratory Behavior; Immobility Response, Tonic; Indoles; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Stress, Physiological; Stress, Psychological; Swimming; Time Factors | 2013 |
A 5-HT1A agonist and a 5-HT2c antagonist reduce social interaction deficit induced by multiple ethanol withdrawals in rats.
Topics: Aminopyridines; Animals; Anxiety; Buspirone; Dose-Response Relationship, Drug; Ethanol; Ethylamines; Indoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior; Substance Withdrawal Syndrome | 2003 |
Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment.
Topics: Aminopyridines; Amygdala; Animals; Anxiety; Behavior, Animal; Dentate Gyrus; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; In Situ Hybridization; Indoles; Male; Motor Activity; Prefrontal Cortex; Propionates; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Thalamus; Ultrasonics; Vocalization, Animal | 2003 |
SB242084, flumazenil, and CRA1000 block ethanol withdrawal-induced anxiety in rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Anxiety; Ethanol; Flumazenil; Indoles; Male; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2004 |
Despite similar anxiolytic potential, the 5-hydroxytryptamine 2C receptor antagonist SB-242084 [6-chloro-5-methyl-1-[2-(2-methylpyrid-3-yloxy)-pyrid-5-yl carbamoyl] indoline] and chlordiazepoxide produced differential effects on electroencephalogram power
Topics: Acoustic Stimulation; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Arousal; Cerebral Cortex; Chlordiazepoxide; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Indoles; Male; Polysomnography; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Sleep; Social Behavior; Stress, Psychological; Theta Rhythm | 2005 |
5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Carbolines; Indoles; Limbic System; Magnetic Resonance Imaging; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2007 |
Drug challenges reveal differences in mediation of stress facilitation of voluntary alcohol drinking and withdrawal-induced anxiety in alcohol-preferring P rats.
Topics: Alcohol Drinking; Aminopyridines; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Buspirone; Dopamine Antagonists; Ethanol; Flumazenil; GABA Modulators; Haloperidol; Indoles; Naloxone; Narcotic Antagonists; Olanzapine; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin Receptor Agonists; Stress, Physiological; Substance Withdrawal Syndrome | 2007 |
Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise.
Topics: Aminopyridines; Animals; Anxiety; Behavior, Animal; Corticosterone; Dose-Response Relationship, Drug; Fluvoxamine; Indoles; Male; Motor Activity; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Agonists; Stress, Psychological | 2008 |
Anxiolytic-like profile of p-MPPI, a novel 5HT1A receptor antagonist, in the murine elevated plus-maze.
Topics: Aminopyridines; Animals; Anxiety; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Piperazines; Serotonin Antagonists | 1997 |
The effects of compounds varying in selectivity as 5-HT(1A) receptor antagonists in three rat models of anxiety.
Topics: Aminopyridines; Animals; Anxiety; Cyclohexane Monoterpenes; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Isoquinolines; Male; Maze Learning; Motor Activity; Pindolol; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Succinimides | 2000 |
5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission.
Topics: Aminopyridines; Animals; Anxiety; Exploratory Behavior; Fluoxetine; Frontal Lobe; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Neurologic Mutants; Microdialysis; Organ Specificity; Phenotype; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Signal Transduction; Stress, Psychological; Synaptic Transmission | 2001 |
Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.
Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Fluoxetine; Grooming; Indoles; Interpersonal Relations; Male; Motor Activity; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sertraline | 2001 |
Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety.
Topics: Aminopyridines; Animals; Anxiety; Compulsive Behavior; Conditioning, Operant; Conflict, Psychological; Diazepam; Dose-Response Relationship, Drug; Drinking; Emotions; Fear; GABA Modulators; Indoles; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reflex, Startle; Reinforcement Schedule; Serotonin Antagonists; Taste | 2002 |