alpha-aminopyridine and Angiogenesis, Pathologic

Topics: Aminopyridines; Animals; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hydroxamic Acids; Indoles; Male; Molecular Targeted Therapy; Neoplasms; Neovascularization, Pathologic; Pancreatic Neoplasms; Prostatic Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides

Topics: Aminopyridines; Animals; Benzamides; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Neovascularization, Pathologic

Topics: Aminopyridines; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Endothelial Cells; Humans; Imidazoles; Mice; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Recurrence, Local; Neoplasms; Neovascularization, Pathologic; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Photochemotherapy; Porphyrins; Protein Kinase Inhibitors; Quinolines; Signal Transduction; Thiazoles; Verteporfin; Xenograft Model Antitumor Assays

Topics: Adenoma, Oxyphilic; Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drosophila; Electron Transport Complex I; Female; Gene Knockout Techniques; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Metformin; Mice; Mice, Knockout; Mice, Nude; NADH Dehydrogenase; Neovascularization, Pathologic; Pyrroles; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Anilides; Animals; Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 4; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Protein Kinase Inhibitors; Pyridines; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

Topics: Aminopyridines; Animals; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Female; Hepatocyte Growth Factor; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Phenylurea Compounds; Piperazines; Proto-Oncogene Proteins c-met; Quinolines; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Animals; Cell Adhesion; Cell Communication; Cell Line, Tumor; Cell Movement; Cell Survival; Chemokine CXCL12; Cluster Analysis; Dendritic Cells, Follicular; Disease Models, Animal; Extracellular Matrix; Gene Expression Profiling; Humans; Lymphoma, Follicular; Mice; Morpholines; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Receptors, CXCR4; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxamic Acids; Immunohistochemistry; Ki-67 Antigen; Mice, Nude; Mutation; Neovascularization, Pathologic; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Predictive Value of Tests; Prognosis; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Uterine Neoplasms; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Anilides; Animals; Antineoplastic Agents; Bevacizumab; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Design; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Hepatocyte Growth Factor; Humans; Inhibitory Concentration 50; Melanoma, Experimental; Mice; Models, Molecular; Molecular Conformation; Monocytes; Neovascularization, Pathologic; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Receptor, TIE-2; Recombinant Proteins; Stromal Cells; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Antigens, Ly; CD11b Antigen; Disease Models, Animal; Female; Flow Cytometry; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Myeloid Cells; Neovascularization, Pathologic; Receptor, Adenosine A2B; Skin Neoplasms; T-Lymphocytes; Tumor Microenvironment; Vascular Endothelial Growth Factor A

Topics: Aminopyridines; Animals; B-Lymphocytes; Benzamides; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Transgenic; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphodiesterase 4 Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A

Topics: Aminopyridines; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Aniline Compounds; Animals; Cell Line, Tumor; Cell Movement; Chick Embryo; Chorioallantoic Membrane; Gene Expression Regulation, Neoplastic; GTP-Binding Protein beta Subunits; Human Umbilical Vein Endothelial Cells; Humans; MCF-7 Cells; NADPH Oxidases; Neovascularization, Pathologic; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, Serotonin, 5-HT1; Serotonin; Signal Transduction; src-Family Kinases

Topics: Aminopyridines; Animals; Antibodies; Antibody Specificity; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Hepatocyte Growth Factor; Humans; Lung Neoplasms; Mice; Models, Biological; Mutation; Neovascularization, Pathologic; Piperazines; Proto-Oncogene Proteins c-met; Quinazolines; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Biological Assay; Caspase 3; Caspases; Cell Line, Tumor; Cell Movement; Chick Embryo; Collagen; Cytochromes c; Drug Combinations; Laminin; Matrix Metalloproteinase 2; Mice; Neoplasms; Neovascularization, Pathologic; Piperazine; Piperazines; Proteoglycans