Compounds > alpha-aminopyridine
Page last updated: 2024-08-21

alpha-aminopyridine and Alveolitis, Fibrosing

alpha-aminopyridine has been researched along with Alveolitis, Fibrosing in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Cao, Z; Chen, Y; Guo, W; Hu, H; Li, B; Liu, J; Pang, J; Song, M; Song, X; Wang, C; Wang, J; Wang, M; Xing, Y; Yang, H; Yang, J; Yang, P; Zhang, T; Zhang, Z1
Bailie, M; Chibucos, L; Christensen, PJ; Dils, AJ; Hazama, M; Horowitz, JC; Matsuo, T; Muraki, Y; Nikam, S; Sisson, TH; Subbotina, N; Tohyama, K1
Cortijo, J; Milara, J; Monleon, D; Morcillo, E; Tenor, H1
Kim, JH; Kim, SW; Kim, TJ; Kim, YK; Kwon, SS; Lee, SY; Park, CK; Rhee, CK; Yoon, HK1
Han, H; Lee, JH; Park, HJ; Park, JW; Park, KH; Park, YH; Sim, da W1
Althage, A; Beyer, C; Chen, CW; Cole, SH; Distler, JH; Gergely, P; Harris, JL; Hsieh, MH; Li, C; Liu, J; Maier, C; Meeusen, S; Ng, N; Pan, S; Schett, G; Seidel, HM; Svensson, EC; Trinh-Minh, T; Xu, X1
Cerdá-Nicolás, M; Cortijo, J; Hatzelmann, A; Iranzo, A; Mata, M; Milara, X; Morcillo, EJ; Ruiz-Saurí, A; Tenor, H1
Ahn, Y; Ertl, RF; Fredriksson, K; Holz, O; Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Magnussen, H; Rennard, SI; Skold, CM; Sugiura, H; Togo, S; Wang, X1
Dunkern, T; Hatzelmann, A; Selige, J1
Salmon, M; Tannheimer, SL; Wright, CD1

Other Studies

10 other study(ies) available for alpha-aminopyridine and Alveolitis, Fibrosing

ArticleYear
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration.
    Signal transduction and targeted therapy, 2022, 05-13, Volume: 7, Issue:1

    Topics: Aminopyridines; Animals; ErbB Receptors; Gefitinib; Inflammation; Mice; Morpholines; Pulmonary Fibrosis; Pyridines; Pyrimidines; Silicosis

2022
Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury.
    Physiological reports, 2018, Volume: 6, Issue:12

    Topics: Alveolar Epithelial Cells; Aminopyridines; Animals; Benzamides; Cells, Cultured; Chemokines; Cyclic AMP; Cyclopropanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Humans; Isoquinolines; Mice, Inbred C57BL; Mice, Transgenic; Phosphodiesterase 4 Inhibitors; Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein D; Pyridines; Tumor Necrosis Factor-alpha

2018
Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine Model.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Aminopyridines; Animals; Benzamides; Bleomycin; Cyclopropanes; Disease Models, Animal; Lung; Magnetic Resonance Spectroscopy; Male; Metabolome; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis

2015
Effect of roflumilast on airway remodelling in a murine model of chronic asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2016, Volume: 46, Issue:5

    Topics: Airway Remodeling; Allergens; Aminopyridines; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Chronic Disease; Cyclopropanes; Cytokines; Disease Models, Animal; Female; Goblet Cells; Humans; Hydroxyproline; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Respiratory Hypersensitivity; T-Lymphocyte Subsets

2016
Roflumilast Ameliorates Airway Hyperresponsiveness Caused by Diet-Induced Obesity in a Murine Model.
    American journal of respiratory cell and molecular biology, 2016, Volume: 55, Issue:1

    Topics: Adiponectin; Aminopyridines; Animals; Benzamides; Cell Proliferation; Cyclopropanes; Cytokines; Diet; Disease Models, Animal; Leptin; Mice, Inbred C57BL; Models, Biological; Obesity; Ovalbumin; Pulmonary Fibrosis; Reactive Oxygen Species; Respiratory Hypersensitivity; T-Lymphocytes

2016
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:4

    Topics: Acyltransferases; Aminopyridines; Animals; Bleomycin; Disease Models, Animal; Disease Progression; Female; Fibrosis; Graft vs Host Disease; Membrane Proteins; Mice, Inbred BALB C; Piperazines; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Scleroderma, Localized; Scleroderma, Systemic; Skin; Transforming Growth Factor beta; Wnt Signaling Pathway

2017
Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury.
    British journal of pharmacology, 2009, Volume: 156, Issue:3

    Topics: Aminopyridines; Animals; Benzamides; Bleomycin; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cyclopropanes; Disease Models, Animal; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Fibrosis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

2009
PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:6

    Topics: Adult; Aminopyridines; Benzamides; Cells, Cultured; Chemotaxis; Collagen; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclooxygenase 1; Cyclooxygenase 2; Cyclopropanes; Dinoprostone; Drug Synergism; Fibroblasts; Fibronectins; Humans; Lung; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Fibrosis; Rolipram; Transforming Growth Factor beta1

2009
The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion.
    Journal of cellular physiology, 2011, Volume: 226, Issue:8

    Topics: Aminopyridines; Benzamides; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Cytokines; Fibroblast Growth Factor 2; Fibroblasts; Gene Expression Profiling; Humans; Interleukin-1beta; Isoenzymes; Lung; Myofibroblasts; Phosphodiesterase 4 Inhibitors; Pulmonary Fibrosis; Pyridines; RNA, Small Interfering; Transfection; Transforming Growth Factor beta

2011
Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts.
    Respiratory research, 2012, Mar-27, Volume: 13

    Topics: Actins; Adrenergic beta-2 Receptor Agonists; Aminopyridines; Benzamides; Cells, Cultured; Chemokine CCL5; Chemokine CXCL10; Connective Tissue Growth Factor; Cyclopropanes; Endothelin-1; Fibroblasts; Fibronectins; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indans; Inflammation; Lung; Phosphodiesterase 4 Inhibitors; Pulmonary Fibrosis; Quinolones; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2012