Page last updated: 2024-08-21

alpha-aminopyridine and Adverse Drug Event

alpha-aminopyridine has been researched along with Adverse Drug Event in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's5 (31.25)24.3611
2020's10 (62.50)2.80

Authors

AuthorsStudies
Bennett, JM; de Botton, S; DiNardo, CD; Döhner, H; Fathi, AT; Frattini, MG; Gong, J; Hasan, M; Kantarjian, HM; Lersch, F; Martin-Regueira, P; Montesinos, P; Schuh, AC; Stein, EM; Vyas, P; Wei, AH; Zeidan, AM1
Ahle, G; Arrondeau, J; Cortot, A; De Crozals, F; Duflot-Boukobza, A; Fallet, V; Lena, H; Naltet, C; Rouby, P1
Fan, Y; Hong, Z; Jia, F; Li, G; Li, J; Li, Y; Liu, Z; Lu, S; Lu, Y; Wu, YL; Zhou, J; Zhou, Q1
Araz, M; Artaç, M; Er, MM; Eryılmaz, MK; Hendem, E1
Gome, J; Hayes, T; Teo, SW1
Barker, D; Burr, L; Dorahy, D; France, M; Greville, H; Middleton, P; Tong, K; Visser, S; Wainwright, C; Wark, P1
Fukuhara, K; Goto, Y; Hayashi, H; Hida, T; Morise, M; Nagasawa, T; Niho, S; Nishio, M; Nogami, N; Ohkura, M; Peltz, G; Sakakibara-Konishi, J; Satouchi, M; Seto, T; Suzuki, M; Takahashi, T; Thurm, H1
Bridges, A; Gleue, CA; Shah, K; Wentworth, A1
Doerler, M; Gambichler, T; Ocker, L; Stranzenbach, R; Susok, L1
Chen, J; Clancy, J; Hibma, J; James, LP; Peltz, G; Ruiz-Garcia, A; Thurm, H1
Catherinot, E; Chabrol, A; Chaumais, MC; Couderc, LJ; Doubre, H; Fraboulet, S; Friard, S; Hamid, AM; Mayenga, M; Metivier, AC; Montani, D; Rivaud, E; Salvator, H; Tcherakian, C1
Bauer, TM; Chioda, MD; Felip, E; Peltz, G; Shaw, AT; Solomon, BJ; Thurm, H1
Arkenau, HT; Auger, KR; Blagden, SP; Fleming, RA; Gazzah, A; Greystoke, A; Mak, G; Mazumdar, J; Nebot, N; Plummer, R; Rizzuto, I; Rogan, D; Soria, JC; Tolson, J; Yan, L; Zhang, J1
Janez, A; Jensterle, M; Kocjan, T1
Arkenau, HT; Auger, KR; Bahleda, R; Blagden, SP; Brown, J; Dean, E; Evans, TR; Fleming, RA; Gan, HK; Gibson, D; Hollebecque, A; Lemech, C; Mazumdar, J; Millward, M; Murray, S; Nebot, N; Peddareddigari, V; Plummer, R; Ranson, M; Singh, R; Soria, JC; Swartz, L; Zalcman, G1
Cai, Y; Chen, F; Chen, Q; Lin, M; Liu, J; Shi, J; Wang, Y; Wang, Z; Zeng, X; Zhang, Y; Zhou, H1

Reviews

1 review(s) available for alpha-aminopyridine and Adverse Drug Event

ArticleYear
[Central nervous system disorders on lorlatinib: How to detect and manage in practice?]
    Bulletin du cancer, 2022, Volume: 109, Issue:4

    Topics: Aminopyridines; Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Central Nervous System Diseases; Drug-Related Side Effects and Adverse Reactions; Humans; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Protein Kinase Inhibitors; Pyrazoles; Quality of Life

2022

Trials

6 trial(s) available for alpha-aminopyridine and Adverse Drug Event

ArticleYear
Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial.
    The Lancet. Oncology, 2021, Volume: 22, Issue:11

    Topics: Aged; Aminopyridines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Mutation; Progression-Free Survival; Random Allocation; Treatment Outcome; Triazines

2021
Lorlatinib Exposure-Response Analyses for Safety and Efficacy in a Phase I/II Trial to Support Benefit-Risk Assessment in Non-Small Cell Lung Cancer.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:5

    Topics: Adult; Aged; Aminopyridines; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypercholesterolemia; Lactams; Lung Neoplasms; Male; Middle Aged; Pyrazoles; Risk Assessment; Treatment Outcome

2021
A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours.
    British journal of cancer, 2019, Volume: 120, Issue:10

    Topics: Aged; Aminopyridines; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxamic Acids; Male; Mesothelioma; Middle Aged; Neoplasms; Progression-Free Survival; Pyridones; Pyrimidinones

2019
Phosphodiesterase 4 inhibition as a potential new therapeutic target in obese women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

    Topics: Adult; Aminopyridines; Benzamides; Body Weight; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Insulin; Menstrual Cycle; Metformin; Molecular Targeted Therapy; Obesity; Phosphodiesterase 4 Inhibitors; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone

2014
A phase I, pharmacokinetic and pharmacodynamic study of GSK2256098, a focal adhesion kinase inhibitor, in patients with advanced solid tumors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Biopsy; Disease-Free Survival; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxamic Acids; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neurofibromin 2; Protein Kinase Inhibitors

2016
An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2006, Volume: 102, Issue:4

    Topics: Adhesives; Adolescent; Adult; Aged; Aminopyridines; Anti-Allergic Agents; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Erythema; Female; Humans; Male; Middle Aged; Pain; Pharmaceutical Vehicles; Stomatitis, Aphthous; Tablets

2006

Other Studies

9 other study(ies) available for alpha-aminopyridine and Adverse Drug Event

ArticleYear
[Chinese Expert Consensus on Management of Special Adverse Effects 
Associated with Lorlatinib].
    Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2022, Aug-20, Volume: 25, Issue:8

    Topics: Aminopyridines; Carcinoma, Non-Small-Cell Lung; China; Consensus; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Humans; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles

2022
Ribociclib-induced hepatotoxicity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:5

    Topics: Aged; Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Protein Kinase Inhibitors; Purines

2023
Ribociclib may potentiate rosuvastatin effect in causing late onset rhabdomyolysis.
    BMJ case reports, 2023, Sep-11, Volume: 16, Issue:9

    Topics: Aminopyridines; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Purines; Rhabdomyolysis; Rosuvastatin Calcium

2023
Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2020, Volume: 19, Issue:3

    Topics: Administration, Intravenous; Adult; Aminophenols; Aminopyridines; Anti-Bacterial Agents; Australia; Benzodioxoles; Case-Control Studies; Chloride Channel Agonists; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Forced Expiratory Volume; Humans; Male; Mutation; Quinolones; Respiratory Function Tests; Respiratory Tract Infections; Symptom Flare Up

2020
Lorlatinib in previously treated anaplastic lymphoma kinase-rearranged non-small cell lung cancer: Japanese subgroup analysis of a global study.
    Cancer science, 2020, Volume: 111, Issue:10

    Topics: Aged; Aged, 80 and over; Aminopyridines; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Humans; Hypercholesterolemia; Lactams; Lactams, Macrocyclic; Middle Aged; Mutation; Neoplasm Metastasis; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles

2020
Cutaneous sarcoid-like drug reaction caused by an anaplastic lymphoma kinase inhibitor.
    Journal of cutaneous pathology, 2021, Volume: 48, Issue:3

    Topics: Adenocarcinoma of Lung; Aged; Aminopyridines; Anaplastic Lymphoma Kinase; Biopsy; Carbazoles; Cell Cycle Proteins; Drug-Related Side Effects and Adverse Reactions; Female; Granuloma; Humans; Lactams; Microtubule-Associated Proteins; Neoplasm Staging; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Sarcoidosis; Serine Endopeptidases; Skin; Withholding Treatment

2021
Acute generalised exanthematous pustulosis after initiation of palbociclib therapy for metastatic breast cancer.
    The Australasian journal of dermatology, 2021, Volume: 62, Issue:3

    Topics: Aged; Aminopyridines; Antineoplastic Agents; Breast Neoplasms; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; Humans; Piperazines; Purines; Pyridines

2021
Lorlatinib - Induced pulmonary arterial hypertension.
    Lung cancer (Amsterdam, Netherlands), 2018, Volume: 120

    Topics: Aminopyridines; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug-Related Side Effects and Adverse Reactions; Dyspnea; Female; Humans; Hypertension, Pulmonary; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Pyrazoles; Vascular Resistance; Walk Test; Withholding Treatment

2018
Clinical Management of Adverse Events Associated with Lorlatinib.
    The oncologist, 2019, Volume: 24, Issue:8

    Topics: Aged; Aminopyridines; Anaplastic Lymphoma Kinase; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Humans; Lactams; Lactams, Macrocyclic; Lung Neoplasms; Middle Aged; Mutation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrazoles; Severity of Illness Index; Treatment Outcome

2019