alpha-aminopyridine has been researched along with Ache in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (16.00) | 18.7374 |
| 1990's | 4 (8.00) | 18.2507 |
| 2000's | 15 (30.00) | 29.6817 |
| 2010's | 19 (38.00) | 24.3611 |
| 2020's | 4 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alcindor, T; Desai, J; Ganjoo, K; Gelderblom, H; Gelhorn, HL; Healey, JH; Martín-Broto, J; Palmerini, E; Shuster, D; Speck, RM; Stacchiotti, S; Tap, WD; van de Sande, M; Wagner, AJ; Wang, Q; Ye, X | 1 |
| Damron, TA | 1 |
| Cheng, YO; Gopinath, D; Shetty, NY; Syeed, MS; Veettil, SK | 1 |
| Huo, B; Jin, L; Li, H; Liu, R; Liu, S; Tang, L; Wang, Y; Yang, T; Zhang, F; Zhao, X | 1 |
| Gao, C; Hong, T; Shen, J; Ti-Jun, D; Xin, L; Yan, C; Zhi-Xiu, M | 1 |
| Nair, AS | 1 |
| Puljak, L | 1 |
| Jiang, F; Li, X; Sun, LC; Wang, Y; Wu, GM; Zeng, W; Zheng, Y; Zhou, LF | 1 |
| Lawson, K | 1 |
| Fan, X; Li, H; Liu, Y; Shao, D; Zhang, D; Zhang, F | 1 |
| Greenwood-Van Meerveld, B; Schulkin, J; Tran, L | 1 |
| Asaki, T; Brown, K; Engel, J; Hasegawa, T; Iso, Y; Iwamoto, Y; Kanemasa, T; Kato, A; Kurose, N; Kyle, DJ; Ni, C; Patel, A; Shet, M; Shintani, T; Tafesse, L; Tsuno, N; Wu, G; Yamaguchi, Y; Yu, J; Zhou, X | 1 |
| Burton, EA; Chartier, S; Habets, G; Jimenez-Andrade, JM; Lin, PS; Mantyh, PW; Thompson, ML; Tsai, J; West, BL | 1 |
| Geisslinger, G; King-Himmelreich, TS; Laarmann, K; Meissner, M; Möser, CV; Niederberger, E; Olbrich, K; Wolters, MC | 1 |
| Arendt-Nielsen, L; Harris, S; Hummel, M; Kapil, R; Knappenberger, T; Kyle, D; O'Keefe, S; Whiteside, GT | 1 |
| Lopez-Garcia, JA; Rivera-Arconada, I; Vicente-Baz, J | 1 |
| Elzein, E; Zablocki, J | 1 |
| Bradshaw, HB; Caterina, MJ; Chung, MK; Coulombe, PA; Huang, SM; Lee, H; Park, U; Walker, JM; Yu, YY | 1 |
| Chen, Q; Chen, R; Dong, Y; Gao, F; Jiang, L; Lin, M; Liu, J; Meng, W; Wang, Z; Xu, T; Zeng, X; Zhong, X; Zhou, H | 1 |
| Broadrup, RL; Brogdon, B; Cassel, JA; Chu, GH; DeHaven, RN; Dolle, RE; Goodman, AJ; Koblish, M; LaBuda, CJ; Le Bourdonnec, B; Saeui, CT; Smith, S; Weaver, DG; Worm, K | 1 |
| Billinton, A; Briggs, M; Brown, AJ; Chessell, IP; Clayton, NM; Eatherton, AJ; Giblin, GM; Goldsmith, P; Haslam, C; Johnson, MR; Mitchell, WL; Naylor, A; Perboni, A; Slingsby, BP; Wilson, AW | 1 |
| Devulder, J | 1 |
| Berman, BM; Lao, L; Li, A; Ren, K; Tan, M; Xin, J; Zhang, RX; Zhang, Y | 1 |
| Alekseev, VV | 1 |
| Bailey, J; McCarthy, C; Smith, RF | 1 |
| Gamper, N; Huang, D; Linley, JE; Pettinger, L | 1 |
| Cooke, I; Goodchild, CS; Kolosov, A; Williams, ED | 1 |
| Genovese, MC; Grossbard, EB; Jones, DA; Kavanaugh, A; Magilavy, DB; Musser, TK; Weinblatt, ME | 1 |
| Assié, MB; Bardin, L; Carilla-Durand, E; Colpaert, FC; Cosi, C; Koek, W; Pauwels, PJ; Tarayre, JP; Vacher, B; Wiesenfeld-Hallin, Z; Xu, XJ | 1 |
| Adriaensen, H; Colpaert, FC; Deseure, K; Koek, W | 1 |
| Miethe, D; Pittrow, D; Ringe, JD; Wegscheider, K | 1 |
| Mueller-Schwefe, G | 1 |
| Müller-Schwefe, G | 1 |
| Dworetzky, SI; Wua, YJ | 1 |
| Biagioni, PA; Lamey, PJ; Murray, B | 1 |
| Cai, Y; Chen, F; Chen, Q; Lin, M; Liu, J; Shi, J; Wang, Y; Wang, Z; Zeng, X; Zhang, Y; Zhou, H | 1 |
| Althaus, M; Hanschmann, A; Klein, T; Magerl, W; Treede, RD | 1 |
| Finlay, BR; Million, R; Whittington, JR | 1 |
| Dunkman, WB; Franciosa, JA; Wilen, MM | 1 |
| Fitton, A; Friedel, HA | 1 |
| Lobisch, M; Lüben, V; Müller, H; Wörz, R | 1 |
| Aigner, M; Herrmann, WM; Hiersemenzel, R; Lobisch, M; Michel, I; Riethmüller-Winzen, H | 1 |
| Greer, RO; Juarez, T; Khandwala, A; Lindenmuth, JE | 1 |
| Hezky, P; Krejcí, I; Proska, J; Rádl, S | 1 |
| Bromm, B; Ganzel, R; Herrmann, WM; Meier, W; Scharein, E | 2 |
| Scheef, W | 1 |
| Hummel, T; Kobal, G | 1 |
| Engel, J; Nickel, B; Szelenyi, I | 1 |
| Scheef, W; Wolf-Gruber, D | 1 |
7 review(s) available for alpha-aminopyridine and Ache
| Article | Year |
|---|---|
COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS.
Topics: Aminopyridines; Humans; Network Meta-Analysis; Pain; Stomatitis, Aphthous | 2023 |
A1 adenosine receptor agonists and their potential therapeutic applications.
Topics: Adenosine A1 Receptor Agonists; Aminopyridines; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Humans; Insulin; Pain; Receptor, Adenosine A1; Thiazoles | 2008 |
Flupirtine in pain management: pharmacological properties and clinical use.
Topics: Aminopyridines; Analgesics; Humans; Pain | 2010 |
[Flupirtin (katadolon): a nonstandard action on pain transmission].
Topics: Aminopyridines; Analgesics, Non-Narcotic; Humans; Pain | 2011 |
Clinical inquiry. What is the most effective way to treat recurrent canker sores?
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Beclomethasone; Cautery; Clobetasol; Eupatorium; Humans; Mouthwashes; Pain; Phytotherapy; Plant Preparations; Secondary Prevention; Stomatitis, Aphthous; Vitamin B 12 | 2011 |
Recent developments on KCNQ potassium channel openers.
Topics: Acrylamides; Aminopyridines; Benzamides; Carbamates; Epilepsy; Humans; Indoles; Ion Channel Gating; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Migraine Disorders; Oxindoles; Pain; Phenylenediamines; Potassium Channels, Voltage-Gated | 2005 |
Flupirtine. A review of its pharmacological properties, and therapeutic efficacy in pain states.
Topics: Aminopyridines; Analgesics; Animals; Humans; Pain | 1993 |
16 trial(s) available for alpha-aminopyridine and Ache
| Article | Year |
|---|---|
Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
Topics: Adult; Aminopyridines; Double-Blind Method; Female; Giant Cell Tumor of Tendon Sheath; Humans; Middle Aged; Pain; Treatment Outcome | 2023 |
A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile.
Topics: Adolescent; Adult; Aminopyridines; Animals; Capsaicin; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Double-Blind Method; Female; Healthy Volunteers; Humans; Male; Middle Aged; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Pressure; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Ultraviolet Rays; Young Adult | 2016 |
A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial.
Topics: Adhesiveness; Administration, Oral; Aminopyridines; Anti-Allergic Agents; China; Double-Blind Method; Drug Administration Schedule; Humans; Pain; Pain Measurement; Recurrence; Stomatitis, Aphthous; Tablets; Treatment Outcome | 2009 |
Effects of fostamatinib (R788), an oral spleen tyrosine kinase inhibitor, on health-related quality of life in patients with active rheumatoid arthritis: analyses of patient-reported outcomes from a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aminopyridines; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Fatigue; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Morpholines; Motor Activity; Oxazines; Pain; Pain Measurement; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Quality of Life; Severity of Illness Index; Syk Kinase; Treatment Outcome | 2013 |
Analgesic efficacy of flupirtine in primary care of patients with osteoporosis related pain. A multivariate analysis.
Topics: Aged; Aminopyridines; Analgesics; Female; Humans; Male; Middle Aged; Multivariate Analysis; Osteoporosis; Pain; Pain Measurement; Prospective Studies | 2003 |
[Parental administration of flupirtine in musculoskeletal pain. Results of a postmarket surveillance study].
Topics: Acute Disease; Aminopyridines; Analgesics; Humans; Injections, Intramuscular; Membrane Potentials; Neurons; Pain; Pain Measurement; Potassium Channels; Receptors, N-Methyl-D-Aspartate | 2004 |
The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Double-Blind Method; Erythema; Female; Humans; Male; Mouth Mucosa; Pain; Placebos; Recurrence; Safety; Stomatitis, Aphthous; Thermography; Time Factors; Treatment Outcome; Wound Healing | 2006 |
An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
Topics: Adhesives; Adolescent; Adult; Aged; Aminopyridines; Anti-Allergic Agents; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Erythema; Female; Humans; Male; Middle Aged; Pain; Pharmaceutical Vehicles; Stomatitis, Aphthous; Tablets | 2006 |
Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia.
Topics: Aminopyridines; Analgesics; Capsaicin; Cross-Over Studies; Cyclopentanes; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; Nervous System Diseases; Pain; Physical Stimulation; Receptors, N-Methyl-D-Aspartate; Treatment Outcome | 2008 |
Clinical trial of flupirtine maleate in patients with migraine.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aminopyridines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Migraine Disorders; Pain; Random Allocation; Sex Factors | 1984 |
[Treatment of tumor pain with flupirtine. Results of a double-blind study versus tramadol].
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Prospective Studies; Tramadol | 1994 |
[Long-term tolerance of flupirtine. Open multicenter study over one year].
Topics: Adult; Aged; Aminopyridines; Analgesics; Chronic Disease; Female; Humans; Long-Term Care; Male; Middle Aged; Musculoskeletal Diseases; Pain; Pain Measurement | 1993 |
A double-blind study of topically applied 5% amlexanox in the treatment of aphthous ulcers.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Aminopyridines; Anti-Inflammatory Agents; Double-Blind Method; Drug Tolerance; Erythema; Humans; Middle Aged; Ointments; Pain; Patient Compliance; Placebos; Recurrence; Stomatitis, Aphthous | 1993 |
The analgesic efficacy of flupirtine in comparison to pentazocine and placebo assessed by EEG and subjective pain ratings.
Topics: Aminopyridines; Analgesics; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Male; Pain; Pain Measurement; Palliative Care; Pentazocine | 1987 |
Analgesic efficacy and safety of oral flupirtine in the treatment of cancer pain.
Topics: Administration, Oral; Aminopyridines; Analgesics; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Palliative Care; Pentazocine; Random Allocation | 1987 |
[Flupirtine in patients with cancer pain].
Topics: Aged; Aminopyridines; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pentazocine; Random Allocation | 1985 |
27 other study(ies) available for alpha-aminopyridine and Ache
| Article | Year |
|---|---|
CORR Insights®: Pexidartinib Provides Modest Pain Relief in Patients With Tenosynovial Giant Cell Tumor: Results From ENLIVEN.
Topics: Aminopyridines; Giant Cell Tumor of Tendon Sheath; Humans; Pain; Pyrroles | 2023 |
Antinociceptive Efficacy of Retigabine and Flupirtine for Gout Arthritis Pain.
Topics: Aminopyridines; Analgesics; Animals; Arthritis, Experimental; Arthritis, Gouty; Behavior, Animal; Carbamates; Disease Models, Animal; Hyperalgesia; KCNQ Potassium Channels; Male; Pain; Phenylenediamines; Rats; Rats, Sprague-Dawley; Uric Acid | 2020 |
5-HT1A Receptors Mediate Analgesia Induced by Emulsified Sevoflurane in Thermal Nociception but Have Little Effect on Chemical Nociception.
Topics: Aminopyridines; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Injections, Spinal; Male; Methyl Ethers; Mice; Nociception; Pain; Pain Threshold; Piperazines; Receptor, Serotonin, 5-HT1A; Sevoflurane; Spinal Cord | 2017 |
Flupirtine: A Less-Explored, Neglected Nonopioid Analgesic.
Topics: Aminopyridines; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pain | 2018 |
Flupirtine, an Effective Analgesic, but Hepatotoxicity Should Limit Its Use.
Topics: Aminopyridines; Analgesics; Chemical and Drug Induced Liver Injury; Humans; Pain | 2018 |
IKKε aggravates inflammatory response via activation of NF-κB in rheumatoid arthritis.
Topics: Aminopyridines; Animals; Arthritis, Experimental; I-kappa B Kinase; Inflammation Mediators; Male; Mice; Mice, Knockout; NF-kappa B; Pain | 2018 |
Flupirtine Is an Effective Analgesic: Is the Associated Rare Liver Injury a Limiting Factor to Its Use?
Topics: Aminopyridines; Analgesics; Humans; Liver; Pain | 2018 |
Suppression of KCNQ/M Potassium Channel in Dorsal Root Ganglia Neurons Contributes to the Development of Osteoarthritic Pain.
Topics: Aminopyridines; Analgesics; Animals; Anthracenes; Arthritis, Experimental; Behavior, Animal; Ganglia, Spinal; Hyperalgesia; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Osteoarthritis; Pain; Rats; Rats, Sprague-Dawley | 2019 |
Importance of CRF receptor-mediated mechanisms of the bed nucleus of the stria terminalis in the processing of anxiety and pain.
Topics: Aminopyridines; Animals; Anxiety; Central Nervous System Agents; Comorbidity; Exploratory Behavior; Hyperalgesia; Male; Maze Learning; Pain; Pain Threshold; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Sensory Gating; Septal Nuclei; Stress, Psychological | 2014 |
Structure-activity relationship studies and discovery of a potent transient receptor potential vanilloid (TRPV1) antagonist 4-[3-chloro-5-[(1S)-1,2-dihydroxyethyl]-2-pyridyl]-N-[5-(trifluoromethyl)-2-pyridyl]-3,6-dihydro-2H-pyridine-1-carboxamide (V116517
Topics: Aminopyridines; Analgesics; Animals; Body Temperature; Calcium; Capsaicin; CHO Cells; Cricetulus; Freund's Adjuvant; Ganglia, Spinal; Humans; Hydrogen-Ion Concentration; Male; Pain; Rats, Sprague-Dawley; Sensory Receptor Cells; Stereoisomerism; Structure-Activity Relationship; TRPV Cation Channels | 2014 |
Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer.
Topics: Aminopyridines; Analgesics; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Dogs; Formaldehyde; Male; Mice; Mice, Nude; Neoplasm Transplantation; Pain; Pain Measurement; Prostatic Neoplasms; Protein Kinases; Pyrroles; Rats; Rats, Sprague-Dawley | 2015 |
The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model.
Topics: Aminopyridines; Animals; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Humans; I-kappa B Kinase; Melanocytes; Melanoma; Melanoma, Experimental; Mice, Inbred C57BL; Mice, Knockout; Pain; Skin Neoplasms | 2016 |
Targeting Kv7 channels in pain pathways.
Topics: Aminopyridines; Animals; Carbamates; Deafness; Epilepsy; Humans; Inflammation; KCNQ Potassium Channels; Long QT Syndrome; Mutation; Neurons; Pain; Pain Management; Phenylenediamines; Protein Conformation | 2017 |
Overexpressed transient receptor potential vanilloid 3 ion channels in skin keratinocytes modulate pain sensitivity via prostaglandin E2.
Topics: Aminopyridines; Animals; Body Temperature; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Humans; Ibuprofen; Keratinocytes; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Piperazines; Recombinant Fusion Proteins; Skin; Temperature; Transgenes; TRPV Cation Channels | 2008 |
Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists.
Topics: Administration, Oral; Aminopyridines; Animals; Dogs; Humans; Male; Microsomes, Liver; Morpholines; Pain; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship | 2009 |
Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.
Topics: Aminopyridines; Animals; Aza Compounds; Brain; Cell Line; CHO Cells; Chronic Disease; Cricetinae; Cricetulus; Drug Discovery; Humans; Indoles; Morpholines; Pain; Rats; Receptor, Cannabinoid, CB2; Structure-Activity Relationship | 2009 |
Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model.
Topics: 5,6-Dihydroxytryptamine; Aminopyridines; Animals; Behavior, Animal; Creatinine; Electroacupuncture; Hyperalgesia; Indoles; Inflammation; Male; Pain; Piperazines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Spinal Cord | 2011 |
M channel enhancers and physiological M channel block.
Topics: Aminopyridines; Animals; Bradykinin; Calcium; Carbamates; CHO Cells; Cricetinae; Cricetulus; Ganglia, Spinal; Hydrogen Peroxide; Inflammation; KCNQ Potassium Channels; Organometallic Compounds; Pain; Phenylenediamines; Phosphatidylinositol 4,5-Diphosphate; Pyridines; Rats; Rats, Wistar; Sensory Receptor Cells; Type C Phospholipases | 2012 |
Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis.
Topics: Aminopyridines; Analgesics; Animals; Bone Neoplasms; Disease Models, Animal; Hyperalgesia; Male; Morphine; Pain; Prostatic Neoplasms; Rats; Rats, Wistar | 2012 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
The 5-HT(1A) receptor agonist F 13640 attenuates mechanical allodynia in a rat model of trigeminal neuropathic pain.
Topics: Aminopyridines; Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Morphine; Muscle Relaxants, Central; Narcotics; Pain; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stress, Mechanical; Trigeminal Neuralgia | 2002 |
[Flupirtine in acute and chronic pain associated with muscle tenseness. Results of a postmarket surveillance study].
Topics: Aminopyridines; Analgesics; Humans; Musculoskeletal Diseases; Neuroprotective Agents; Pain; Pain Measurement; Treatment Outcome | 2003 |
Adverse effects of long-term amrinone administration in congestive heart failure.
Topics: Abdomen; Aged; Aminopyridines; Amrinone; Cough; Heart Failure; Humans; Liver Function Tests; Male; Middle Aged; Nausea; Pain; Time Factors; Vomiting | 1983 |
Synthesis and analgesic activity of some quinazoline analogs of anpirtoline.
Topics: Aminopyridines; Analgesics; Animals; Hot Temperature; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Piperidines; Pyridines; Quinazolines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Structure-Activity Relationship; Tramadol | 2000 |
Effects of flupirtine on the pain-related evoked potential and the spontaneous EEG.
Topics: Adult; Aminopyridines; Analgesics; Electroencephalography; Evoked Potentials; Female; Humans; Male; Pain | 1988 |
Possible involvement of noradrenergic descending pain-modulating pathways in the mode of antinociceptive action of flupirtine, a novel non-opioid analgesic.
Topics: Aminopyridines; Analgesics; Animals; Efferent Pathways; Male; Norepinephrine; Pain; Rats; Rats, Inbred Strains | 1988 |
Pentazocine and flupirtine effects on spontaneous and evoked EEG activity.
Topics: Aminopyridines; Brain; Double-Blind Method; Electric Stimulation; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Humans; Male; Pain; Pentazocine | 1986 |