alpha-aminopyridine has been researched along with ADPKD in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Geng, X; He, J; Huang, H; Jenny Lu, HA; Jia, Y; Jin, W; Li, M; Li, X; Meng, J; Qiu, Z; Shao, G; Wang, L; Wang, S; Xu, Y; Yang, B; Zhang, S; Zhou, H | 1 |
| Cebotaru, L; Yanda, MK | 1 |
| Asawa, RR; Chen, Y; Danchik, C; Jadhav, A; Martinez, NJ; Simeonov, A; Trott, JF; Voss, T; Wallace, DP; Weiss, RH; Zakharov, A | 1 |
| Ida, T; Ikeda, K; Kitani, T; Kusaba, T; Matoba, S; Tamagaki, K; Tomita, A; Uehara, M; Watanabe-Uehara, N; Yamada, T; Yamashita, N | 1 |
| Abu Aboud, O; Baloglu, E; Chen, X; Chmiel, KJ; Dionne, LK; Hwang, VJ; Li, X; Mahjoub, MR; Senapedis, W; Shim, K; Trott, J; Weiss, RH; Zhou, X | 1 |
| Cebotaru, L; Liu, Q; Yanda, MK | 1 |
6 other study(ies) available for alpha-aminopyridine and ADPKD
| Article | Year |
|---|---|
Inhibiting Focal Adhesion Kinase Ameliorates Cyst Development in Polycystin-1-Deficient Polycystic Kidney Disease in Animal Model.
Topics: Aminopyridines; Animals; Benzamides; Cell Culture Techniques; Cell Proliferation; Disease Models, Animal; Dogs; Epithelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxamic Acids; Mice; Mice, Inbred C57BL; Polycystic Kidney, Autosomal Dominant; Pyrazines; Signal Transduction; Sulfonamides | 2021 |
VX-809 mitigates disease in a mouse model of autosomal dominant polycystic kidney disease bearing the R3277C human mutation.
Topics: Aminopyridines; Animals; Benzodioxoles; Cystic Fibrosis Transmembrane Conductance Regulator; Cysts; Female; Kidney; Male; Mice; Mice, Inbred C57BL; Polycystic Kidney, Autosomal Dominant | 2021 |
A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.
Topics: Acrylamides; Aminopyridines; Animals; Cell Line; Cell Survival; Drug Repositioning; Epithelial Cells; Humans; Kidney; Mice; Polycystic Kidney, Autosomal Dominant; Protein Kinase C; Signal Transduction | 2020 |
Diverse Receptor Tyrosine Kinase Phosphorylation in Urine-Derived Tubular Epithelial Cells from Autosomal Dominant Polycystic Kidney Disease Patients.
Topics: Adult; Aged; Aminopyridines; Animals; Cell Line; Cell Proliferation; Cells, Cultured; Cysts; Dogs; Epithelial Cells; Female; Humans; Kidney; Kidney Tubules, Distal; Madin Darby Canine Kidney Cells; Male; Middle Aged; Phosphorylation; Piperazines; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Urine | 2020 |
Anticystogenic activity of a small molecule PAK4 inhibitor may be a novel treatment for autosomal dominant polycystic kidney disease.
Topics: Acrylamides; Aminopyridines; Animals; Apoptosis; beta Catenin; Cell Proliferation; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelial Cells; Female; Humans; Kidney; Male; Mice; Mice, Transgenic; NAD; Nicotinamide Phosphoribosyltransferase; Organ Culture Techniques; p21-Activated Kinases; Phosphorylation; Polycystic Kidney, Autosomal Dominant; Receptors, Cell Surface; Signal Transduction; TRPP Cation Channels | 2017 |
A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.
Topics: Aminopyridines; Animals; Benzodioxoles; Calcium; Cell Line; Cell Proliferation; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Cysts; Heat-Shock Proteins; Kidney; Mice; Mice, Inbred C57BL; Polycystic Kidney, Autosomal Dominant; Transcription Factor CHOP | 2018 |