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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and beta-Glucuronidase Deficiency

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with beta-Glucuronidase Deficiency in 1 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Research Excerpts

ExcerptRelevanceReference
"This study used a murine model of mucopolysaccharidosis type VII (MPS VII) to test whether pathological and functional CNS defects could be corrected by expressing beta-glucuronidase via bilateral intrastriatal injection of adeno-associated virus type 5 (AAV5betagluc) vectors."1.34Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS. ( Chen, YH; Chiorini, JA; Davidson, BL; He, X; Heth, JA; Liu, G; Martins, I, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, G1
Chen, YH1
He, X1
Martins, I1
Heth, JA1
Chiorini, JA1
Davidson, BL1

Other Studies

1 other study available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and beta-Glucuronidase Deficiency

ArticleYear
Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2007, Volume: 15, Issue:2

    Topics: Adenoviridae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blotting, Western;

2007